Bopa tlhahlobo ea phosphokinase

Creatine phosphokinase (CPK) ke enzyme 'meleng. E fumanoa haholo pelong, bokong le mesifa ea masapo. Sengoloa sena se bua ka tlhahlobo ea ho lekanya palo ea CPK maling.

Ho hlokahala sampole ea mali. Sena se ka nkoa mothapong. Tsamaiso e bitsoa venipuncture.

Teko ena e ka phetoa ho feta matsatsi a 2 kapa a 3 haeba u le mokuli sepetlele.

Ha ho litokisetso tse khethehileng tse hlokahalang boholo ba nako.

Bolella mofani oa tlhokomelo ea bophelo ka meriana efe kapa efe eo u e sebelisang. Lithethefatsi tse ka eketsang litekanyo tsa CPK li kenyelletsa amphotericin B, li-anesthetics tse ling, li-statin, li-fibrate, dexamethasone, joala le cocaine.

U ka utloa bohloko bo fokolang ha nale e kentsoe ho hula mali. Batho ba bang ba utloa feela ho hlaba kapa ho hlaba habohloko. Kamora moo, ho kanna ha ba le ho tsitsipana.

Ha kakaretso ea CPK e le holimo haholo, hangata ho bolela hore ho bile le kotsi kapa khatello ea maikutlo meleng ea mesifa, pelong kapa bokong.

Ho ka etsahala hore kotsi ea mesifa ea mesifa e teng. Ha mosifa o senyehile, CPK e kena ka har'a mali. Ho fumana mofuta ofe oa CPK o phahameng ho thusa ho tseba hore na ke lisele life tse senyehileng.

Teko ena e ka sebelisoa ho:

• Hlahloba lefu la pelo
• Hlahloba sesosa sa bohloko ba sefuba
• Etsa qeto ea hore na mesifa e senyehile hakae kapa hore na e senyehile hakae
• Fumana dermatomyositis, polymyositis le maloetse a mang a mesifa
• Bolella phapang pakeng tsa lefu le kotsi la tšoaetso ea mali le tšoaetso ea kamora 'ts'ebetso

Mohlala le nako ea ho phahama kapa ho oa ha maemo a CPK e ka ba bohlokoa ho etseng tlhahlobo. Sena ke 'nete haholoholo haeba ho belaelloa lefu la pelo.

Maemong a mangata liteko tse ling li sebelisoa ho fapana le kapa ka teko ena ho fumana lefu la pelo.

Kakaretso ea litekanyetso tse tloaelehileng tsa CPK:

• Li-micrograms tse 10 ho isa ho tse 120 ka litha e le nngwe (mcg / L)

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li leka liteko tse fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.

Maemo a phahameng a CPK a ka bonoa ho batho ba nang le:

• Kotsi ea boko kapa stroke
• Ho tsitsinyeha
• Delirium ea thothomela
• Dermatomyositis kapa polymyositis
• Ho tshoha ha motlakase
• Lefu la pelo
• Ho ruruha ha mesifa ea pelo (myocarditis)
• Lefu la lung lefu (pulmonary infarction)
• Li-dystrophies tsa mesifa
• Myopathy
• Rhabdomyolysis

Maemo a mang a ka fanang ka sephetho se setle sa liteko a kenyelletsa:

• Hypothyroidism
• Hyperthyroidism
• Pericarditis kamora lefu la pelo

Likotsi tse amanang le ho huloa mali li nyane empa li ka kenyelletsa:

• Ho tsoa mali a mangata
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Hematoma (mali a bokellanang ka tlasa letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Liteko tse ling li lokela ho etsoa ho fumana sebaka se nepahetseng sa tšenyo ea mesifa.

Lintho tse ka amang liphetho tsa liteko li kenyelletsa catheterization ea pelo, liente tsa mesifa, ho sithabela mesifa, ho buuoa haufinyane le boikoetliso bo boima.

Teko ea CPK

• Teko ea mali

Anderson JL. St segment elevation acute myocardial infarction le mathata a infarction ea "myocardial". Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 73.

Carty RP, Pincus MR, Sarafraz-Yazdi E. K'hemik'hale ea methapo ea mafu. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. Philadelphia, PA: Elsevier; 2017: khaolo ea 20.

Mccullough PA. Sebopeho pakeng tsa lefu la renal le lefu la pelo. Ka: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Lefu la pelo la Braunwald: Buka ea bongaka ea meriana ea pelo. 11th ed. Philadelphia, PA: Elsevier; 2019: khaolo ea 98.

Nagaraju K, Gladue HS, Lundberg IE. Maloetse a ho ruruha a mesifa le tse ling tsa myopathies. Ka: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, bahlophisi. Kelley le Firestein's Bookbook ea Rheumatology. 10th ed. Philadelphia, PA: Elsevier Saunders; 2017: khaolo ea 85.