Teko ea moroto oa 17-Ketosteroids

17-ketosteroids ke lintho tse etsahalang ha 'mele o roba lihormone tsa banna tsa thobalano tse bitsoang androgens le lihormone tse ling tse hlahisoang ke litšoelesa tsa adrenal ho banna le basali, le ka li-testes tse tona.

Ho hlokahala sampole ea lihora tse 24. U tla hloka ho bokella moroto oa hau ho feta lihora tse 24. Mofani oa hao oa tlhokomelo ea bophelo o tla u joetsa hore na u ka etsa sena joang. Latela litaelo hantle ho netefatsa liphetho tse nepahetseng.

Mofani oa hau o tla u kopa hore u emise meriana efe kapa efe e ka amang litholoana tsa liteko. Etsa bonnete ba hore o bolella mofani oa hau ka meriana eohle eo u e nkang. Tsena li kenyelletsa:

• Lithibela-mafu
• Aspirin (haeba u le aspirin ea nako e telele)
• Lipilisi tsa thibelo ea bokhachane
• Diuretics (lipilisi tsa metsi)
• Estrogen

U SE KE UA emisa ho noa moriana pele u bua le mofani oa litšebeletso.

Teko e kenyelletsa ho ntša metsi ka mokhoa o tloaelehileng. Ha ho na bothata.

Mofani oa hau a ka laela tlhahlobo ena haeba u na le matšoao a lefu le amanang le maemo a sa tloaelehang a androgens.

Litekanyetso tse tloaelehileng ke tse latelang:

• E motona: 7 ho isa ho 20 mg ka lihora tse 24
• Mosali: 5 ho isa ho 15 mg ka lihora tse 24

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li leka liteko tse fapaneng. Bua le ngaka ea hau ka se boleloang ke sephetho sa hau sa liteko.

Maemo a eketsehileng a li-ketosteroid tse 17 a ka bakoa ke:

• Mathata a tšoelesa ea adrenal joalo ka hlahala, Cushing syndrome
• Ho se leka-lekane ha lihormone tsa thobalano ho basali (polycystic ovary syndrome)
• Kankere ea mahe a bomme
• Kankere ea testicular
• Thyroid e feteletseng
• Botenya
• Khatello ea maikutlo

Methati e fokotsehileng ea li-ketosteroid tse 17 e ka bakoa ke:

• Litšoelesa tsa adrenal ha li etse lihormone tsa tsona tse lekaneng (lefu la Addison)
• Tšenyo ea liphio
• Tšoelesa ea pituitary ha e etse lihormone tsa eona tse lekaneng (hypopituitarism)
• Ho tlosoa li-testicles (castration)

Ha ho na likotsi ka tlhahlobo ena.

• Sampole ea moroto

Bertholf RL, Cooper M, Mariha WE. Cortex ea Adrenal. Ka: Rifai N, ed. Tietz ea Buka ea Khemistri ea Kliniki le Diagnostics ea Limolek'hule. La 6th. St Louis, MO: Elsevier; 2018: khaolo ea 66.

Teko ea Nakamoto J. Endocrine. Ka: Jameson JL, De Groot LJ, oa Kretser DM, et al, eds. Endocrinology: Batho ba baholo le bana. La 7th. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 154.