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Letsatsi La Creation: 26 Phupu 2021
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Phekolo ea Hormone (HT) e sebelisa hormone e le 'ngoe kapa ho feta ho phekola matšoao a ho khaotsa ho ilela khoeli. HT e sebelisa estrogen, progestin (mofuta oa progesterone), kapa ka bobeli. Ka linako tse ling testosterone e boetse e eketsoa.

Matšoao a ho khaotsa ho ilela khoeli a kenyelletsa:

  • Ho chesa haholo
  • Mofufutso oa bosiu
  • Mathata a boroko
  • Ho omella ha botshehadi
  • Ho tšoenyeha
  • Ho fetoha maikutlo
  • Thahasello e nyane ho thobalano

Ka mor'a ho khaotsa ho ilela khoeli, 'mele oa hao o khaotsa ho etsa estrogen le progesterone. HT e ka phekola matšoao a ho khaotsa ho ilela khoeli a u tšoenyang.

HT e na le likotsi. E ka eketsa menyetla ea ho:

  • Ho koala mali
  • Kankere ea matsoele
  • Lefu la pelo
  • Leqeba
  • Majoe a majoe

Leha ho na le matšoenyeho ana, ho basali ba bangata, HT ke tsela e bolokehileng ea ho phekola matšoao a ho khaotsa ho ilela khoeli.

Hajoale, litsebi ha li hlake hantle hore na o nka HT nako e kae. Lihlopha tse ling tsa litsebi li fana ka maikutlo a hore o ka nka HT bakeng sa matšoao a ho ilela khoeli nako e telele haeba ho se na lebaka la bongaka la ho khaotsa ho noa. Bakeng sa basali ba bangata, tekanyetso e tlase ea HT e kanna ea lekana ho laola matšoao a likhathatso. Tekanyo e tlase ea HT e na le litla-morao tse fokolang. Tsena ke litaba tsa ho buisana le mofani oa tlhokomelo ea bophelo ba hau.


HT e tla ka mefuta e fapaneng. U kanna ua hloka ho leka mefuta e fapaneng pele u fumana e u sebetsang hantle.

Estrogen ea kena:

  • Ho fafatsa nko
  • Lipilisi kapa matlapa a nooang ka molomo
  • Letlalo la letlalo
  • Matlalo a letlalo, a tlotsitsoeng lethekeng kapa mpeng
  • Litlolo tsa botšehaling kapa matlapa a botšehaling ho thusa ho omella le bohloko ka thobalano
  • Lesale la bosali

Basali ba bangata ba sebelisang estrogen le ba ntseng ba e-na le popelo le bona ba hloka ho noa progestin. Ho nka lihormone ka bobeli ho theola menyetla ea kankere ea endometrial (uterine). Basali ba tlositsoeng popelo ba ke ke ba tšoaroa ke mofetše oa endometrium. Kahoo, ho khothalletsoa estrogen feela.

Progesterone kapa progestin e kena:

  • Lipilisi
  • Matlalo a letlalo
  • Litlolo tsa basali
  • Li-suppositories tsa bosali
  • Sesebelisoa sa intrauterine kapa sistimi ea intrauterine

Mofuta oa HT o laetsoeng ke ngaka ea hau o ka itšetleha ka matšoao ao u nang le 'ona a ho khaotsa ho ilela khoeli. Mohlala, lipilisi kapa lipache li ka alafa mofufutso bosiu. Masale a ka botšehaling, litlolo, kapa matlapa a thusa ho imolla ho oma ha botšehaling.


Buisanang ka melemo le likotsi tsa HT le mofani oa hau.

Ha u nka estrogen le progesterone hammoho, ngaka ea hau e ka fana ka tlhahiso ea e 'ngoe ea lipampiri tse latelang:

Phekolo ea li-cyclic hormone e buelloa khafetsa ha o qala ho ilela khoeli.

  • U nka estrogen e le pilisi kapa ue sebelisa ka mokhoa oa patch matsatsi a 25.
  • Progestin e eketsoa pakeng tsa matsatsi a 10 le a 14.
  • Le sebelisa estrogen le progestin hammoho bakeng sa matsatsi a 25 a setseng.
  • Ha u nke lihormone tsa matsatsi a 3 ho isa ho a mahlano.
  • U kanna oa ba le ho tsoa mali khoeli le khoeli ka kalafo ea cyclic.

Phekolo e kopaneng ke ha u noa estrogen le progestin hammoho letsatsi le leng le le leng.

  • U kanna oa ba le ho tsoa mali ho sa tloaelehang ha u qala kapa u fetohela kemisong ena ea HT.
  • Basali ba bangata ba emisa ho tsoa mali nakong ea selemo se le seng.

Ngaka ea hau e ka u fa meriana e meng haeba u e-na le matšoao a matla kapa u le kotsing e kholo ea lefu la ho fokola ha masapo. Mohlala, o kanna oa nka testosterone, hormone ea monna, ho ntlafatsa takatso ea hau ea thobalano.


HT e ka ba le litla-morao, ho kenyelletsa:

  • Ho senya
  • Ho opeloa ke letsoele
  • Ho tšoaroa ke hlooho
  • Feto-fetoha
  • Ho nyekeloa
  • Ho boloka metsi
  • Ho tsoa mali khafetsa

Bolella ngaka ea hau haeba u hlokomela litla-morao. Ho fetola lethal dose kapa mofuta oa HT eo u e nkang ho ka thusa ho fokotsa litla-morao tsena. U SE KE UA fetola lethal dose kapa ua khaotsa ho nka HT pele u bua le ngaka ea hau.

Haeba u tsoa mali ka botšehaling kapa matšoao a mang a sa tloaelehang nakong ea HT, letsetsa ngaka.

Etsa bonnete ba hore o tsoela pele ho bona ngaka ea hau bakeng sa tlhahlobo e tloaelehileng ha u nka HT.

Mefuta ea HRT; Phekolo ea estrogen - mefuta; Mefuta ea ERT ea kalafo ea li-hormone; Phekolo ea Hormone - mefuta; Menopause - mefuta ea phekolo ea li-hormone; Mefuta ea HT; Mefuta ea li-hormone tsa menopausal

Maikutlo a komiti ea ACOG che. 565: Phekolo ea Hormone le lefu la pelo. Gynecol e thibelang. 2013; 121 (6): 1407-1410. PMID: 23812486 pubmed.ncbi.nlm.nih.gov/23812486/.

Cosman F, de Beur SJ, LeBoff MS, le al. Tataiso ea ngaka ea thibelo le kalafo ea lefu la masapo. Osteoporos Int. 2014; 25 (10): 2359-2381. PMID: 25182228 phatlalalitsoe.ncbi.nlm.nih.gov/25182228/.

de Villiers TJ, Holo ea JE, Pinkerton JV, et al. Polelo e ntlafalitsoeng ea tumellano ea lefats'e ka kalafo ea li-hormone tsa menopausal. Boemo ba leholimo. 2016; 19 (4): 313-315. PMID: 27322027 e fetotsoe.ncbi.nlm.nih.gov/27322027/.

Lobo RA. Ho khaotsa ho ilela khoeli le ho hlokomela mosali ea holileng tsebong: endocrinology, litlamorao tsa khaello ea estrogen, litlamorao tsa kalafo ea lihormone le mekhoa e meng ea kalafo. Ka: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Kakaretso ea mafu a basali. La 7th. Philadelphia, PA: Elsevier; 2017: khaolo ea 14.

Magowan BA, Owen P, Thomson A. Phekolo ea ho khaotsa ho ilela khoeli le li-hormone. Ka: Magowan BA, Owen P, Thomson A, eds. Clinical Obstetrics le Gynecology. La 4 ed. Elsevier; 2019: khaolo ea 9.

Stuenkel CA, Davis SR, Gompel A, le al. Kalafo ea matšoao a ho khaotsa ho ilela khoeli: Mokhatlo oa Endocrine tataiso ea boits'oaro ba bongaka. J Kliniki ea Endocrinol Metab. 2015; 100 (11): 3975-4011. PMID: 26444994 e fetotsoe.ncbi.nlm.nih.gov/26444994/.

  • Phekolo ea Phetolo ea Hormone
  • Ho khaotsa ho ilela khoeli

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