Nephropathy ea IgA

IgA nephropathy ke lefu la liphio leo lithibela-mafu tse bitsoang IgA li hahang liseleng tsa liphio. Nephropathy ke tšenyo, mafu kapa mathata a mang a liphio.

Nephropathy ea IgA e boetse e bitsoa lefu la Berger.

IgA ke protheine, e bitsoang antibody, e thusang 'mele ho loants'a mafu. Nephropathy ea IgA e etsahala ha protheine e ngata e kentsoe liphio. IgA e aha kahare ho methapo e nyane ea mali ea liphio. Mekhoa ea liphio e bitsoang glomeruli ea chesa ebile ea senyeha.

Boloetse bona bo ka hlaha ka tšohanyetso (bo hlobaetsang), kapa ba mpefala butle butle ho feta lilemo tse ngata (glomerulonephritis e sa foleng).

Mabaka a kotsi a kenyelletsa:

• Nalane ea botho kapa ea lelapa ea IgA nephropathy kapa Henoch-Schönlein purpura, mofuta oa vasculitis o amang likarolo tse ngata tsa 'mele
• Morabe o mosweu kapa wa Asia

Nephropathy ea IgA e ka hlaha ho batho ba lilemo tsohle, empa hangata e ama banna ba lilemong tsa bocha ho fihlela lilemong tsa bo-30.

Ho kanna ha ba le matšoao a lilemo tse ngata.

Ha ho na le matšoao, a ka kenyelletsa:

• Moroto o nang le mali o qalang nakong kapa kapele ka mor'a ts'oaetso ea phefumoloho
• Likarolo tse phetoang tsa moroto o lefifi kapa o nang le mali
• Ho ruruha ha matsoho le maoto
• Matšoao a lefu le sa foleng la liphio

Hangata nephropathy ea IgA e fumanoa ha motho ea se nang matšoao a mang a liphio a na le karolo e le 'ngoe kapa tse' maloa tsa moroto o lefifi kapa o nang le mali.

Ha ho na liphetoho tse ikhethang tse bonoeng nakong ea tlhahlobo ea 'mele. Ka linako tse ling, khatello ea mali e ka ba holimo kapa ho ba le ho ruruha ha 'mele.

Liteko li kenyelletsa:

• Teko ea mali ea urea nitrogen (BUN) ho lekanya tšebetso ea liphio
• Teko ea mali ea Creatinine ho lekanya tšebetso ea liphio
• Liphio biopsy ho netefatsa phumano
• Ho hlahloba urinal
• Immunoelectrophoresis ea moroto

Morero oa kalafo ke ho imolla matšoao le ho thibela kapa ho liehisa ho hloleha ho sa foleng ha renal.

Kalafo e ka kenyelletsa:

• Angiotensin-converting enzyme (ACE) inhibitors le angiotensin receptor blockers (ARBs) ho laola khatello e phahameng ea mali le ho ruruha (edema)
• Corticosteroids, lithethefatsi tse ling tse hatellang sesole sa 'mele
• Oli ea litlhapi
• Meriana ea ho theola k'holeseterole

Letsoai le maro a ka thibeloa ho ruruha. Ho ka buelloa phepo e nepahetseng ea protheine maemong a mang.

Qetellong, batho ba bangata ba tlameha ho phekoloa mafu a sa foleng a liphio mme ba ka hloka dialysis.

Nephropathy ea IgA e mpefala butle butle. Maemong a mangata, ha e mpefale ho hang. Boemo ba hau bo ka mpefala haeba o na le:

• Khatello ea mali e phahameng
• Liprotheine tse ngata morotong
• Ho eketseha ha BUN kapa maemo a creatinine

Bitsa mofani oa tlhokomelo ea bophelo haeba u na le moroto o nang le mali kapa u hlahisa moroto o monyane ho feta tloaelo.

Nephropathy - IgA; Lefu la Berger

• Anatomy ea liphio

Feehally J, Floege J. Immunoglobulin Nephropathy le IgA vasculitis (Henoch-Schönlein purpura). Ho: Feehally J, Floege J, Tonelli M, Johnson RJ, bangoli. Kakaretso ea Nephrology ea Kliniki. La 6th. Philadelphia, PA: Elsevier; 2019: khaolo ea 23.

Saha MK, Pendergraft WF, Jennette JC, Falk RJ. Lefu la mantlha la glomerular. Ka: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, li-eds. Brenner le Rector ea Liphio. 11th ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 31.