Calcium pyrophosphate ramatiki

Calcium pyrophosphate dihydrate (CPPD) ramatiki ke lefu le kopaneng le ka bakang tlhaselo ea ramatiki. Joaloka gout, likristale li theha manonyellong. Empa ho ramatiki ena, likristale ha lia etsoa ka uric acid.

Ho beha calcium pyrophosphate dihydrate (CPPD) ho baka mofuta ona oa ramatiki. Ho aha ha k'hemik'hale ena ho theha likristale lefufung la manonyello. Sena se lebisa litlhaselong tsa ho ruruha ha manonyeletso le bohloko mangoleng, manonyeletso a letsoho, maqaqailaneng, mahetleng le manonyeletsong a mang. Ho fapana le gout, lenonyeletso la monoana o motona oa leoto ha le amehe.

Har'a batho ba baholo, CPPD ke sesosa se tloaelehileng sa ramatiki ea tšohanyetso (a hlobaetsang) kopanong e le 'ngoe. Tlhaselo e bakoa ke:

• Ho lematsa lenonyello
• Ente ea Hyaluronate lenonyellong
• Boloetse ba bongaka

CPPD ramatiki e ama haholo batho ba tsofetseng hobane ho senyeha ha manonyeletso le lefu la masapo a osteoarthritis ho eketseha ka lilemo. Ts'enyo e joalo e kopaneng e eketsa tloaelo ea ts'ebetso ea CPPD. Leha ho le joalo, ramatiki ea CPPD ka linako tse ling e ka ama batho ba bacha ba nang le maemo a kang:

• Hemochromatosis
• Lefu la Parathyroid
• Ho hloleha ha renal ho itšetlehileng ka Dialysis

Maemong a mangata, ramatiki ea CPPD ha e bake matšoao a letho. Ho e-na le hoo, li-x-ray tsa manonyeletso a amehileng joalo ka mangole li bontša litšobotsi tsa khalsiamo.

Batho ba bang ba nang le li-depositi tse sa foleng tsa CPPD manonyellong a maholo ba ka ba le matšoao a latelang:

• Bohloko
• Ho ruruha
• Mofuthu
• Bofubelu

Litlhaselo tsa bohloko ba manonyeletso li ka nka likhoeli. Ho kanna ha ba le matšoao lipakeng tsa litlhaselo.

Ho batho ba bang ramatiki ea CPPD e baka tšenyo e mpe lenonyellong.

CPPD ramatiki e ka hlaha mokokotlong, ka bobeli tlase le holimo. Khatello ea methapo ea mokokotlo e ka baka bohloko matsohong kapa maotong.

Hobane matšoao a ts'oana, ramatiki ea CPPD e ka ferekanngoa le:

• Gouty ramatiki (gout)
• Osteoarthritis
• Ramatiki ea ramatiki

Maemo a mangata a ramatiki a bontša matšoao a tšoanang. Ho hlahloba ka hloko mokelikeli o kopaneng bakeng sa likristale ho ka thusa ngaka ho lemoha boemo.

O kanna oa feta litekong tse latelang:

• Tlhatlhobo e kopaneng ea mokelikeli ho fumana lisele tse tšoeu tsa mali le likristale tsa calcium pyrophosphate
• Li-x-ray tse kopaneng ho batla tšenyo e kopaneng le li-depositi tsa calcium libakeng tse kopaneng
• Liteko tse ling tse kopantsoeng tsa ho nka litšoantšo tse kopaneng joalo ka CT scan, MRI kapa ultrasound, ha ho hlokahala
• Liteko tsa mali ho lekola maemo a amanang le calcium pyrophosphate ramatiki

Kalafo e ka kenyelletsa ho tlosa mokelikeli ho imolla khatello lenonyellong. Ho kenngoa nale ho lenonyeletso 'me mokelikeli oa lakaletsoa. Tse ling tsa likhetho tse tloaelehileng tsa kalafo ke tsena:

• Liente tsa Steroid: ho phekola manonyeletso a ruruhileng haholo
• Oral steroids: ho phekola manonyeletso a mangata a ruruhileng
• Meriana e khahlanong le ho ruruha (li-NSAID): ho kokobetsa bohloko
• Colchicine: ho phekola litlhaselo tsa ramatiki ea CPPD
• Bakeng sa ramatiki e sa foleng ea CPPD manonyellong a mangata methotrexate kapa hydroxychloroquine e ka ba thuso

Batho ba bangata ba sebetsa hantle ka kalafo ho fokotsa bohloko bo bohloko ba manonyeletso. Moriana o kang colchicine o ka thusa ho thibela litlhaselo tse iphetang. Ha ho na kalafo ea ho tlosa likristale tsa CPPD.

Tšenyo e sa feleng ea lenonyello e ka hlaha ntle le kalafo.

Bitsa mofani oa tlhokomelo ea bophelo haeba u hlaseloa ke ho ruruha le manonyeletso.

Ha ho na mokhoa o tsebahalang oa ho thibela lefu lena. Leha ho le joalo, ho sebetsana le mathata a mang a ka bakang ramatiki ea CPPD ho ka mpefatsa boemo.

Ho etela batho khafetsa ho ka thusa ho thibela tšenyo e sa feleng ea manonyeletso a amehileng.

Calcium pyrophosphate dihydrate deposition lefu; Lefu la CPPD; Matšoao a bohloko / a sa foleng a CPPD; Pseudogout; Pyrophosphate arthropathy; Chondrocalcinosis

• Ho ruruha ho kopaneng ha mahetla
• Osteoarthritis
• Sebopeho sa kopanyo

Andrés M, Sivera F, Pascual E. Therapy bakeng sa CPPD: likhetho le bopaki. Cur ea Rheumatol Rep. 2018; 20 (6): 31. PMID: 29675606 e fetotsoe.ncbi.nlm.nih.gov/29675606/.

Edwards NL. Maloetse a Crystal deposition. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 257.

Terkeltaub R. Lefu la kristale ea calcium: pyrophosphate dihydrate le calcium phosphate ea mantlha. Ka: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, bahlophisi. Kelley le Firestein's Bookbook ea Rheumatology. 10th ed. Philadelphia, PA: Elsevier; 2017: khaolo ea 96.