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Feberu e tloaelehileng ea Mediterranean (FMF) ke lefu le sa tloaelehang le fetisoang ke malapa (a futsitsoeng). E kenyelletsa feberu e pheta-phetoang le ho ruruha hangata ho amang lera la mpa, sefuba kapa la manonyeletso.

Hangata FMF e bakoa ke phetoho ea liphatsa tsa lefutso e bitsoang MEFV. Jini ena e etsa protheine e kenyelletsang ho laola ho ruruha. Lefu lena le hlaha feela ho batho ba amohetseng likopi tse peli tsa lefutso le fetotsoeng, e le 'ngoe ho tsoa ho motsoali ka mong. Sena se bitsoa autosomal recessive.

Hangata FMF e ama batho ba lesika la Mediterranean. Tsena li kenyelletsa Bajode bao eseng ba Ashkenazi (Sephardic), Maarmenia le Maarabia. Batho ba merabe e meng le bona ba ka ameha.

Hangata matšoao a qala pakeng tsa lilemo tse 5 ho isa ho tse 15. Litlhaselo li ka fapana ka matla a matšoao. Hangata batho ha ba na matšoao lipakeng tsa litlhaselo.

Matšoao a ka kenyelletsa likarolo tse pheta-phetoang tsa:


  • Bohloko ba mpeng
  • Bohloko ba sefuba bo bohale 'me bo mpefala ha u hema
  • Feberu kapa feberu e fapanyetsanang le feberu
  • Bohloko bo kopaneng
  • Liso tsa letlalo (liso) tse khubelu le ho ruruha 'me li bophara ba lisenthimithara tse 5 ho isa ho tse 20

Haeba tlhahlobo ea lefutso e bontša hore u na le MEFV Phetoho ea lefutso 'me matšoao a hau a tšoana le mokhoa o tloaelehileng, ho tla fumanoa hore na o fumane eng. Liteko tsa laboratori kapa x-ray li ka thibela mafu a mang a ka bang teng ho thusa ho etsa hore motho a fumanoe.

Methati ea liteko tse ling tsa mali e ka ba holimo ho feta e tloaelehileng ha e etsoa nakong ea tlhaselo. Liteko li ka kenyelletsa:

  • Palo e felletseng ea mali (CBC) e kenyelletsang palo e tšoeu ea lisele tsa mali
  • C-protein e sebetsang ho hlahloba ho ruruha
  • Sekhahla sa methapo ea methapo ea methapo (ESR) ho lekola ho ruruha
  • Teko ea fibrinogen ho lekola ho koala mali

Morero oa kalafo bakeng sa FMF ke ho laola matšoao. Colchicine, moriana o fokotsang ho ruruha, o ka thusa nakong ea tlhaselo mme o ka thibela litlhaselo tse ling. E ka thusa hape ho thibela bothata bo tebileng bo bitsoang systemic amyloidosis, e tloaelehileng ho batho ba nang le FMF.


Li-NSAID li ka sebelisoa ho phekola feberu le bohloko.

Ha ho na pheko e tsebahalang ea FMF. Batho ba bangata ba ntse ba tsoela pele ho ba le litlhaselo, empa palo le boima ba litlhaselo li fapane ho ea ka motho le motho.

Amyloidosis e ka lebisa ho senyeha ha liphio kapa ho se khone ho monya limatlafatsi lijong (malabsorption). Mathata a ho emola ho basali le banna le ramatiki le ona ke mathata.

Ikopanye le mofani oa hau haeba uena kapa ngoana oa hau le ba le matšoao a boemo bona.

Tloaelehileng paroxysmal polyserositis; Peritonitis ea nako le nako; Ho ipolaea khafetsa; Benign paroxysmal peritonitis; Lefu la nako le nako; Feberu ea nako le nako; FMF

  • Tekanyo ea mocheso

Leetsi JW. Hereditary syndromes ea feberu ea nako le nako le mafu a mang a tšoaetsanoang ke mafu. Ka: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, bahlophisi. Buka ea Nelson ea Pediatrics. La 21 Ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 188.


Shohat M. Feberu e tloaelehileng ea Mediterranean. Ka: MP ea Adam, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, eds. Litlhahlobo [Inthanete]. University of Washington, Seattle, WA: 2000 Aug 8 [e ntlafalitsoeng 2016 Dec 15]. PMID: 20301405 www.pubmed.ncbi.nlm.nih.gov/20301405/.

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