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Atherosclerosis, eo ka linako tse ling e bitsoang "ho thatafala ha methapo," e etsahala ha mafura, k'holeseterole le lintho tse ling li haella maboteng a methapo. Li-deposit tsena li bitsoa plaques. Ha nako e ntse e feta, lipoleiti tsena li ka koala methapo kapa tsa li thiba ka ho felletseng 'me tsa baka mathata' meleng oohle.

Atherosclerosis ke lefu le tloaelehileng.

Atherosclerosis hangata e hlaha ka botsofali. Ha u ntse u tsofala, ho hahoa ha plaque ho fokotsa methapo ea hau le ho e thatafatsa. Liphetoho tsena li thatafalletsa mali ho phalla ka tsona.

Ho koaloa masapo methapong ena e patisaneng 'me ho thibele phallo ea mali. Likotoana tsa lejoe le tsona li ka petsoha 'me tsa fetela methapong e menyenyane ea mali, ea li koala.

Li-blockages tsena li lapa lisele tsa mali le oksijene. Sena se ka baka tšenyo kapa lefu la lisele. Ke sesosa se tloaelehileng sa lefu la pelo le stroke.

Likarolo tse phahameng tsa k'holeseterole ea mali li ka baka ho thatafala ha methapo ea mali ha e sa le monyane.

Bakeng sa batho ba bangata, maemo a phahameng a k'holeseterole a bakoa ke lijo tse nang le mafura a mangata haholo.


Lintlha tse ling tse ka tlatselletsang ho thatafala ha methapo li kenyelletsa:

  • Lefu la tsoekere
  • Nalane ea lelapa ea ho thatafala ha methapo
  • Khatello ea mali e phahameng
  • Ho hloka boikoetliso
  • Ho ba motenya haholo kapa ho ba motenya
  • Ho tsuba

Atherosclerosis ha e bake matšoao ho fihlela phallo ea mali karolong e 'ngoe ea' mele e lieha kapa e koaloa.

Haeba methapo e fepelang pelo e fokola, phallo ea mali e ka fokotseha kapa ea emisa. Sena se ka baka bohloko ba sefuba (angina e tsitsitseng), phefumoloho e khuts'oane le matšoao a mang.

Methapo e mosesane kapa e koetsoeng e ka baka mathata mala, liphio, maoto le bokong.

Mofani oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele' me a mamele pelo le matšoafo ka stethoscope. Atherosclerosis e ka baka molumo o lerata kapa o butsoang ("bruit") holim'a mothapo.

Batho bohle ba baholo ba fetang lilemo tse 18 ba lokela ho hlahlojoa khatello ea mali selemo se seng le se seng. Ho ka hlokahala litekanyo tse ngata khafetsa bakeng sa ba nang le nalane ea ho bala khatello ea mali e phahameng kapa ba nang le mabaka a kotsi a khatello e phahameng ea mali.


Ho hlahlojoa k'holeseterole ho khothalletsoa ho batho bohle ba baholo. Litataiso tse kholo tsa naha li fapana ka lilemo tse khothalelitsoeng ho qala liteko.

  • Ho hlahloba ho lokela ho qala pakeng tsa lilemo tse 20 ho isa ho tse 35 bakeng sa banna le lilemo tse 20 ho isa ho tse 45 bakeng sa basali.
  • Ho pheta-pheta liteko ha ho hlokahale bakeng sa lilemo tse hlano bakeng sa batho ba baholo ba nang le maemo a tloaelehileng a k'holeseterole.
  • Ho ka phetoa liteko ho ka hlokahala haeba liphetoho tsa bophelo li etsahala, joalo ka keketseho e kholo ea boima kapa phetoho ea lijo.
  • Ho hlokahala liteko tse ngata khafetsa bakeng sa batho ba baholo ba nang le nalane ea k'holeseterole e phahameng, lefu la tsoekere, mathata a liphio, lefu la pelo, stroke le maemo a mang

Liteko tse 'maloa tsa ho nka litšoantšo li ka sebelisoa ho bona hore na mali a tsamaea hantle hakae methapong ea hau.

  • Liteko tsa Doppler tse sebelisang maqhubu a ultrasound kapa a molumo
  • Magnetic resonance arteriography (MRA), mofuta o khethehileng oa scan ea MRI
  • Lisebelisoa tse khethehileng tsa CT tse bitsoang CT angiography
  • Li-arteriograms kapa angiography tse sebelisang li-x-ray le lintho tse fapaneng (tseo ka linako tse ling li bitsoang "dae") ho bona tsela ea phallo ea mali kahare ho methapo

Liphetoho tsa bophelo li tla fokotsa menyetla ea lefu la atherosclerosis. Lintho tseo u ka li etsang li kenyelletsa:


  • Khaotsa ho tsuba: Ena ke phetoho ea bohlokoahali eo u ka e etsang ho fokotsa menyetla ea lefu la pelo le setorouku.
  • Qoba lijo tse mafura: Ja lijo tse nang le phepo e ntle tse se nang mafura le k’holeseterole. Kenyelletsa litšebeletso le litholoana tsa meroho tse 'maloa tsa letsatsi le letsatsi. Ho eketsa litlhapi lijong tsa hau bonyane habeli ka beke ho ka ba molemo. Leha ho le joalo, u se ke ua ja tlhapi e halikiloeng.
  • Fokotsa hore na u noa joala bo bokae: Meeli e khothalletsoang ke seno se le seng ka letsatsi bakeng sa basali, habeli ka letsatsi bakeng sa banna.
  • Fumana boikoetliso ba 'mele khafetsa: Ho ikoetlisa ka matla a itekanetseng (joalo ka ho tsamaea ka potlako) matsatsi a 5 ka beke metsotso e 30 ka letsatsi haeba u le boima bo botle. Bakeng sa ho theola boima ba 'mele, ikoetlisa metsotso e 60 ho isa ho e 90 ka letsatsi. Bua le mofani oa hau pele u qala moralo o mocha oa boikoetliso, haholo haeba u fumanoe u na le lefu la pelo kapa u kile ua ba le lefu la pelo.

Haeba khatello ea mali e phahame, ho bohlokoa hore o e theole le ho e boloka e le taolong.

Morero oa kalafo ke ho fokotsa khatello ea mali e le hore o be le monyetla o tlase oa ho ba le mathata a bophelo bo botle a bakoang ke khatello e phahameng ea mali. Uena le mofani oa thepa ea hau le lokela ho ipehela pakane ea khatello ea mali.

  • Se ke oa emisa kapa oa fetola meriana ea khatello e phahameng ea mali ntle le ho bua le mofani oa thepa ea hau.

Mofani oa hau a kanna a batla hore u noe moriana oa li-cholesterol tse sa tloaelehang kapa khatello e phahameng ea mali haeba phetoho ea bophelo e sa sebetse. Sena se tla itšetleha ka:

  • Lilemo tsa hau
  • Meriana eo u e nkang
  • Kotsi ea litla-morao tsa meriana e ka bang teng
  • Hore na o na le lefu la pelo kapa mathata a mang a phallo ea mali
  • Hore na oa tsuba kapa o nonne haholo
  • Hore na o na le lefu la tsoekere kapa mabaka a mang a kotsi a lefu la pelo
  • Hore na o na le mathata a mang a bongaka, joalo ka lefu la liphio

Mofani oa hau a ka fana ka tlhahiso ea ho noa aspirin kapa moriana o mong ho thusa ho thibela maqeba a mali ho theha methapo ea hau. Meriana ena e bitsoa lithethefatsi tsa "antiplatelet". U SE KE ua noa aspirin pele u bua le mofani oa hau.

Ho theola boima ba 'mele haeba o nonne haholo mme o fokotsa tsoekere maling haeba o na le lefu la tsoekere kapa lefu la tsoekere le ka thusa ho fokotsa menyetla ea ho ba le atherosclerosis.

Atherosclerosis e ke ke ea etsolloa hang ha e se e etsahetse. Leha ho le joalo, phetoho ea bophelo le kalafo ea li-cholesterol tse ngata li ka thibela kapa tsa liehisa ts'ebetso hore e mpefale. Sena se ka thusa ho fokotsa menyetla ea ho ba le lefu la pelo le seterouku ka lebaka la atherosclerosis.

Maemong a mang, lejoe lena ke karolo ea ts'ebetso e bakang ho fokola ha lerako la mothapo. Sena se ka lebisa ho phunyehang mothapong o bitsoang aneurysm. Li -neurysms li ka buleha (ho phatloha). Sena se baka tšollo ea mali e ka behang bophelo kotsing.

Ho thatafala ha methapo; Arteriosclerosis; Plaque buildup - methapo; Hyperlipidemia - atherosclerosis; Cholesterol - atherosclerosis

  • Ho lokisa mpa ea aortic aneurysm - ho bula - ho tsoa
  • Ho lokisa aortic aneurysm - endovascular - ho tsoa
  • Aspirin le lefu la pelo
  • Ho hloleha ha pelo - ho tsoa
  • Ho hloleha ha pelo - seo u lokelang ho se botsa ngaka ea hau
  • Khatello ea mali e phahameng - seo u lokelang ho se botsa ngaka ea hau
  • Mofuta oa 2 oa lefu la tsoekere - o ka botsa ngaka ea hau eng
  • Carotid stenosis - X-ray ea methapo ea letsohong le letšehali
  • Carotid stenosis - X-ray ea mothapo o nepahetseng
  • Pono e atolositsoeng ea atherosclerosis
  • Thibelo ea lefu la pelo
  • Ts'ebetso ea kholo ea atherosclerosis
  • Angina
  • Matšoafo
  • Bahlahisi ba k'holeseterole
  • Coronary artery ballo angioplasty - letoto la lihlooho tse

Arnett DK, Blumenthal RS, Albert MA, Buroker AB, le al. Tataiso ea 2019 ACC / AHA mabapi le thibelo ea mantlha ea lefu la pelo le methapo: kakaretso ea phethahatso: tlaleho ea American College of Cardiology / American Heart Association Task Force mabapi le Litataiso tsa Tloaelo ea Bongaka. J Ke Coll Cardiol. 2019; 74 (10): 1376-1414. PMID: 30894319 e phatlalalitsoeng.ncbi.nlm.nih.gov/30894319/.

Genest J, Libby P. Lipoprotein mathata le lefu la pelo. Ka: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Lefu la pelo la Braunwald: Buka ea bongaka ea meriana ea pelo. 11th ed. Philadelphia, PA: Elsevier; 2019: khaolo ea 48.

James PA, Oparil S, Carter BL, le al. Tataiso e thehiloeng bopaking ea 2014 bakeng sa taolo ea khatello e phahameng ea mali ho batho ba baholo: tlaleho ho tsoa ho litho tsa phanele tse khethiloeng ho Komiti ea Naha ea Borobeli e Kopaneng (JNC 8). JAMA. 2014; 311 (5): 507-520. PMID: 24352797 e fetotsoe.ncbi.nlm.nih.gov/24352797/.

Libby P. Biology ea vascular ea atherosclerosis. Ka: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Lefu la pelo la Braunwald: Buka ea bongaka ea meriana ea pelo. 11th ed. Philadelphia, PA: Elsevier; 2019: khaolo ea 44.

Letšoao AR. Mosebetsi oa pelo le oa potoloho. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 47.

Webosaete ea Sesole sa Ts'ireletso ea US. Polelo ea hoqetela ea hoqetela: tšebeliso ea molao bakeng sa thibelo ea mantlha ea lefu la pelo ho batho ba baholo: meriana ea thibelo. E ntlafalitsoe ka la 13 Pulungoana 2016. E fihlile ka la 28 Pherekhong 2020. www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/statin-use-in-adult-preventive-medication1.

Whelton PK, Carey RM, Aronow WS, le al. 2017 ACC / AHA / AAPA / ABC / ACPM / AGS / APhA / ASH / ASPC / NMA / PCNA tataiso bakeng sa thibelo, ho lemoha, ho lekola le ho laola khatello e phahameng ea mali ho batho ba baholo: tlaleho ea American College of Cardiology / American Basebetsi ba Mokhatlo oa Pelo mabapi le Litataiso tsa Tloaelo ea Bongaka. J Ke Coll Cardiol. 2018; 71 (19): 2199-2269. PMID: 2914653 phatlalalitsoe.ncbi.nlm.nih.gov/29146533/.

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