Nutrigenomics ke eng mme e ka ntlafatsa lijo tsa hau?

Litaba

• Saense ka Mora ho Nutrigenomics
• Kamoo U ka e Sebelisang Kateng
• Tlhahlobo bakeng sa

Keletso ea lijo e ne e tloaetse ho latela ntho e latelang: Latela molaoana ona oa boholo bo le bong (lula hole le tsoekere, tlisa mafura a tlase ntho e ngoe le e ngoe) ho ja hantle. Empa ho latela lefapha le hlahang la mahlale le bitsoang nutrigenomics, tsela eo ea ho nahana e haufi le ho felloa ke nako joalo ka lijo tsa sopho ea kh'abeche (ee, eo e ne e hlile e le ntho). (Bona hape: Lijo tse 9 tsa Feshene li Wacky Ho Lumela)

"Nutrigenomics ke thuto ea hore na liphatsa tsa lefutso li sebelisana joang le lijo tseo re li jang," ho bolela Clayton Lewis, CEO le cofounder ea Arivale, k'hamphani e sebelisang sampole ea mali ho hlahloba liphatsa tsa lefutso tsa hau ebe e u kopanya le setsebi sa phepo e nepahetseng ho hlalosa moralo o motle oa ho ja. bakeng sa mmele wa hao. "Li sebetsa 'moho joang ho etsa hore re phele hantle kapa re bake maloetse?"

Ha palo e ntseng e eketseha ea liteko tsa lefutso malapeng li tla u joetsa, u liphatsa tsa lefutso ebile u ikhethile ka tlhaho ho tsoa ho mang kapa mang sebakeng sa hau sa boikoetliso. Lewis o re: "Sena se bolela hore ha ho na lijo tse phetseng hantle ka boholo bo lekanang."

Mohlala: Le hoja mafura a phetseng hantle a kang avocado kapa oli ea mohloaare a fumane setempe sa tumello ea saense, batho ba bang ba atisa ho nona ka lijo tse nang le mafura a mangata ho feta ba bang. Liphatsa tsa lefutso tsa hau li ka boela tsa ama tsela eo u monyang limatlafatsi hantle joaloka vithamine D. Esita le haeba u ja lithane tsa salmon tse nang le D-rich, mefuta e itseng ea liphatsa tsa lefutso e ka 'na ea bolela hore u ntse u hloka tlatsetso.

Ho fumana moralo oa liphatsa tsa lefutso ho ka u thusa ho tseba hantle hore na 'mele oa hau o hloka ho ba eng ka ho fetisisa. "Ho hlile ho bua ka ho iketsetsa motho ka mong," ho bolela Lewis. Nahana ka keletso ea khale ea lijo joaloka 'mapa oa pampiri. Tlhahisoleseling e teng, empa ho thata haholo ho tseba hore na e hokae uena li setšoantšong. Nutrigenomics e tšoana le ho ntlafatsa ho Google Maps-e u bolella hantle moo u leng teng, hore u tle u fihle moo u batlang ho ea teng.

"Ho utloisisa phepo e nepahetseng le bophelo bo botle, re hloka ho utloisisa hore na biology ea rona e ikhethang e sebetsa joang ho boloka 'mele ea rona e tsitsitse," ho bolela Neil Grimmer, CEO le mothehi oa Habit, qalo ea ho sebelisa limatlafatsi, liteko tsa metabolic le litsebi tsa phepo ho u thusa ho theha mekhoa e metle ea ho ja.

U tla qala ho utloa ka phetoho ena ea papali ea phepo e nepahetseng haholo-phuputso ea batho ba 740 ba lijo tse entsoeng ke KIND e boletse esale pele hore keletso ea phepo e nepahetseng e fumanoeng tšimong e tla ba e 'ngoe ea mekhoa e mehlano ea lijo tsa 2018. Mona ke seo u se hlokang ho tseba ka hore na li-nutrigenomics li ka ama moralo oa hau oa bophelo bo botle joang.

Saense ka Mora ho Nutrigenomics

"Le hoja lentsoe 'nutrigenomics' le tsebahala lilemong tse ka bang 15 tse fetileng, khopolo ea hore re arabela ka tsela e fapaneng lijong e 'nile ea e-ba teng ka nako e telele," ho bolela Grimmer. Lekholong la pele la lilemo B.C. mongoli oa Selatine Lucretius o ile a ngola, ‘Sejo sa motho a le mong se ka ba chefo e babang ho ba bang.’ ”

Ho latellana ha liphatsa tsa lefutso tsa motho ho fetotse filosofi eo hore e be ntho eo u ka e sebelisang. Ka ho sekaseka sampole ea mali (Arivale e sebelisa lisampole tse bokelletsoeng ke laboratoring ea lehae ha Habit e u romella lisebelisoa tsa ho nka sampole e nyane lapeng), bo-ramahlale ba ka bona liphatsa tsa lefutso tsa biomarkers-tse amang tsela eo 'mele oa hau o sebetsang ka eona limatlafatsi tse itseng.

Nka ka mohlala liphatsa tsa lefutso tsa FTO, tse hlahisang protheine e thusang ho laola takatso ea hau ea ho felisa ntho e ngoe le e ngoe e sehatsetsing. "Mofuta o le mong, kapa mofuta o mong, oa lefutso lena," -o bitsoang FTO rs9939609, haeba u batla ho fumana saense - "e ka 'na ea etsa hore u fumane boima ba' mele," ho bolela Grimmer. "Lab e etsa liteko bakeng sa biomarker ena ea lefutso mme e sebelisa tlhaiso-leseling eo, hammoho le letheka la hao, ho lekola kotsi ea ho ba motenya."

Kahoo, leha o ka ba hantle AF hona joale ka lebaka la metabolism e potlakileng le boinehelo ho HIIT, liphatsa tsa lefutso tsa hau li ka bonts'a likotsi life kapa life tsa katoloso e ka bang teng ea thekeng nakong e tlang.

Kamoo U ka e Sebelisang Kateng

Ka lebaka la sehlahisoa sa li-start-ups tse ncha tse kang Arivale le Tloaelo, tlhahlobo ea lapeng kapa ho hula mali ho ka u fa tlaleho e felletseng (joalo ka eo ke e fumaneng ha ke ne ke tloaetse ho nthusa ho fetola filosofi ea ka ea bophelo bo botle ho tloha boima ba 'mele ho ea ho bophelo bo botle ) ho u bolella hantle hore na u behe eng poleiting ea hao le hore na ke lijo life tse ka bang kotsi ho uena.

Empa saense e ntse e tsoela pele. Tlhahlobo ea 2015 ea lipatlisiso tsa phepo e nepahetseng, e phatlalalitsoeng ho Genomics e sebelisitsoeng le ea ho fetolela, o ile a bontša hore le hoja ka sebele bopaki bo tšepisa, lithuto tse ngata ha li eo bonnete litloaelano lipakeng tsa liphatsa tsa lefutso tse atisang ho hlahlojoa litekong tsa phepo ea 'mele le mafu a mang a amanang le phepo. Ka mantsoe a mang, hobane feela tlaleho ea nutrigenomics e supa phetoho ea FTO ha ho bolele hore u ka sebele ho ba boima bo feteletseng.

Bokamoso ba Nutrigenomics bo na le bokhoni bo eketsehileng ba ho iketsetsa motho. "Ha rea ​​​​lokela ho nahana feela ka liphatsa tsa lefutso empa hape le hore na liprotheine le metabolite tse ling tse anngoeng ke liphatsa tsa lefutso tsa hau li arabela joang lijong," ho bolela Grimmer.

Sena ke se tsejoang e le "multi-omic" data-genomics e kopantsoeng le lintlha tse mabapi le "metabolomics" (limolek'hule tse nyane) le "proteomics" (liprotheine), ho hlalosa Lewis. Ka Senyesemane se hlakileng, ho bolela ho atamela haufi le ho feta kamoo lerato la hau la avocado le tla ama letheka la hao le likotsi tsa mafu a itseng.

Tloaelo e se e ntse e tsoela pele ka data ea multi-omic-hona joale, lisebelisoa tsa bona tsa lapeng li ka hlahloba hore na 'mele oa hau o arabela joang lijong ka ho bapisa sampuli ea mali e potlakileng le lisampole tse nkiloeng ka mor'a hore u noe tšisinyeho e nang le limatlafatsi. "Haufinyane tjena ho bile le tsoelo-pele ea baeloji ea limolek'hule, tlhahlobo ea data, le saense ea phepo e nepahetseng e re thusitseng ho sebelisa data ena ho theha likhothaletso maemong a botho," Grimmer o re. Mona ke ho ntlafatsa mmapa oa hau oa bophelo bo botle.

Tlhahlobo bakeng sa