Teko ea Mali ea SHBG

Litaba

• Teko ea mali ea SHBG ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea mali ea SHBG?
• Ho etsahalang nakong ea tlhahlobo ea mali ea SHBG?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea mali ea SHBG?
• Litšupiso

Teko ea mali ea SHBG ke eng?

Tlhahlobo ena e lekanya litekanyetso tsa SHBG maling a hau. SHBG e emetse li-hormone tsa thobalano tse tlamang globulin. Ke protheine e entsoeng ke sebete 'me e itšoarella ka lihomone tsa thobalano tse fumanoang ho banna le basali. Lihormone tsena ke:

• Testosterone, hormone ea mantlha ea thobalano ho banna
• Dihydrotestosterone (DHT), hormone e 'ngoe ea botona le botšehali
• Estradiol, mofuta oa estrogen, hormone e kholo ea thobalano ho basali

SHBG e laola hore na li-hormone tsena li fetisetsoa liseleng tsa 'mele hakae. Le ha SHBG e khomarela lihormone tsena tse tharo, tlhahlobo ea SHBG e sebelisoa haholo ho sheba testosterone. Methati ea SHBG e ka bonts'a haeba ho na le testosterone e ngata haholo kapa e nyane haholo e sebelisoang ke 'mele.

Mabitso a mang: testosterone-estrogen e tlamang globulin, TeBG

E sebelisetsoa eng?

Hangata ho sebelisoa teko ea SHBG ho fumana hore na testosterone e ea lisele tsa 'mele hakae. Methati ea testosterone e ka lekanyetsoa tekong e arohaneng e bitsoang testosterone e felletseng. Teko ena e bonts'a hore na testosterone e kae 'meleng, empa eseng hore na' mele o sebelisa bokae.

Ka linako tse ling tlhahlobo e felletseng ea testosterone e lekane ho etsa tlhahlobo. Empa batho ba bang ba na le matšoao a hormone e ngata haholo kapa e fokolang hoo liphetho tsa liteko tsa testosterone li ke keng tsa e hlalosa. Maemong ana, tlhahlobo ea SHBG e ka laeloa ho fana ka tlhaiso-leseling e batsi mabapi le hore na testosterone e fumaneha hakae 'meleng.

Hobaneng ha ke hloka tlhahlobo ea mali ea SHBG?

U kanna oa hloka tlhahlobo ena haeba u na le matšoao a maemo a sa tloaelehang a testosterone, haholoholo haeba tlhahlobo e felletseng ea testosterone e sa khone ho hlalosa matšoao a hau. Bakeng sa banna, hangata e laeloa haeba ho na le matšoao a maemo a tlase a testosterone. Bakeng sa basali, hangata e laeloa haeba ho na le matšoao a maemo a phahameng a testosterone.

Matšoao a maemo a tlase a testosterone ho banna a kenyelletsa:

• Koloi e tlase ea thobalano
• Ho thata ho fumana erection
• Mathata a ho emola

Matšoao a maemo a phahameng a testosterone ho basali a kenyelletsa:

• Khōlo e feteletseng ea 'mele le sefahleho
• Ho teba ha lentsoe
• Mathata a ho ilela khoeli
• Makhopho
• Boima ba 'mele
• Mathata a ho emola

Ho etsahalang nakong ea tlhahlobo ea mali ea SHBG?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea SHBG.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Haeba liphetho tsa hau li bonts'a maemo a hau a SHBG a le tlase haholo, ho kanna ha bolela hore protheine ha e itšoare ka testosterone e lekaneng. Sena se lumella testosterone e ngata e sa hokahaneng hore e fumanehe tsamaisong ea hau. E ka baka testosterone e ngata haholo ho ea lisele tsa 'mele oa hau.

Haeba maemo a hau a SHBG a phahame haholo, ho ka bolela hore protheine e itšoarella ka testosterone e ngata haholo. Kahoo ha ho na hormone e ngata, 'me lisele tsa hau li kanna tsa se fumane testosterone e lekaneng.

Haeba maemo a hau a SHBG a le tlase haholo, e ka ba sesupo sa:

• Hypothyroidism, boemo boo 'mele oa hau o sa etse lihormone tse lekaneng tsa qoqotho
• Mofuta oa 2 oa lefu la tsoekere
• Ho sebelisa meriana ea steroid hampe
• Cushing’s syndrome, boemo boo ’mele oa hao o etsang hormone e ngata haholo e bitsoang cortisol
• Bakeng sa banna, e ka bolela mofets'e oa maselese kapa litšoelesa tsa adrenal. Litšoelesa tsa Adrenal li kaholimo ho liphio mme li thusa ho laola ho otla ha pelo, khatello ea mali le mesebetsi e meng ea 'mele.
• Bakeng sa basali, e ka bolela polycystic ovary syndrome (PCOS). PCOS ke lefu le tloaelehileng la "hormone" le amang basali ba belehang. Ke e 'ngoe ea lisosa tse ka sehloohong tsa ho hloka thari ha basali.

Haeba maemo a hau a SHBG a phahame haholo, e ka ba sesupo sa:

• Lefu la sebete
• Hyperthyroidism, boemo boo 'mele oa hau o etsang lihormone tse ngata tsa qoqotho
• Mathata a ho ja
• Bakeng sa banna, e ka bolela bothata ka li-testicles kapa pituitary gland. Tšoelesa ea pituitary e ka tlasa boko mme e laola mesebetsi e mengata ea 'mele.
• Bakeng sa basali, e ka bolela bothata ka tšoelesa ea pituitary, kapa lefu la Addison. Boloetse ba Addison ke boloetse boo litšoelesa tsa adrenal li sa khoneng ho etsa lihormone tse itseng tse lekaneng.

Mofani oa hao oa tlhokomelo ea bophelo a ka odara liteko tse ling tse joalo ka liteko tsa testosterone kapa estrogen ho thusa ho etsa tlhahlobo. Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa thepa ea hau.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea mali ea SHBG?

Maemo a SHBG hangata a phahame ho bana ba bong ka bobeli, ka hona tlhahlobo e lula e sebelisoa bakeng sa batho ba baholo.

Litšupiso

1. Li-Lab tsa Accesa [Marang-rang]. El Segundo (CA): Acessa Labs; c2018. Teko ea SHBG; [e ntlafalitsoeng 2018 Aug 1; e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.accesalabs.com/SHBG-Test
2. ACOG: Lingaka tsa Basali tsa Tlhokomelo ea Bophelo [Internet]. Washington D.C.: Koleji ea Amerika ea Litsebi tsa Litsebi le Lingaka tsa Gynecologists; c2017. Polycystic Ovary Syndrome (PCOS); 2017 Jun [e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.acog.org/Patients/FAQs/Polycystic-Ovary-Syndrome-PCOS
3. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Cushing Syndrome; [e ntlafalitsoeng 2017 Nov 29; e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/conditions/cushing-syndrome
4. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Polycystic Ovary Syndrome; [e ntlafalitsoeng 2018 Jun 12; e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/conditions/polycystic-ovary-syndrome
5. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Thobalano ya Hormone e Kopanyang Globulin (SHBG); [e ntlafalitsoeng 2017 Nov 5; e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/sex-hormone-binding-globulin-shbg
6. Mayo Clinic: Mayo Medical Laboratories [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1995–2018. Boitsebiso ba Teko: SHBG: Globulin e Tlamang ka Thobalano ea ho Kopanela Liphate (SHBG), Serum: Kliniki le Tlhaloso; [e qotsitsoeng 2018 Aug 4]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9285
7. Mokhatlo oa Naha oa Kankere [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Bukantswe ya NCI ya Dipehelo tsa Kankere: DHT; [e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/dht
8. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali; [e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. Setsi sa Naha sa Lefu la Ts'oaetso le Mafu a Ts'oaetso le Liphio [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Lefu la Mabitla; 2017 Sep [e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.niddk.nih.gov/health-information/endocrine-diseases/graves-disease
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11. Quest Diagnostics [Inthanete]. Diagnostics ea Quest; c2000–2017. Setsi sa Teko: Ho Kopana Hormone e Kopanyang Globulin (SHBG); [e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.questdiagnostics.com/testcenter/TestDetail.action?ntc=30740
12. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2018. Health Encyclopedia: Ho Kopana Hormone ea Thobalano Globulin (Mali); [e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=shbg_blood
13. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2018. Testosterone: Liphetho; [e ntlafalitsoeng 2017 May 3; e qotsitsoeng 2018 Aug 4]; [li-skrini tse ka bang 8]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/testosterone/hw27307.html#hw27335
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Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.