Teko ea Karolo ea Thromboplastin Time (PTT)

Litaba

• Teko ea PTT (karoloana ea thromboplastin time) ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea PTT?
• Ho etsahalang nakong ea tlhahlobo ea PTT?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea PTT?
• Litšupiso

Teko ea PTT (karoloana ea thromboplastin time) ke eng?

Teko ea karoloana ea thromboplastin (PTT) e lekanya nako eo e e nkang hore mali a thehe. Ka tloaelo, ha u khaola kapa u tsoa kotsi e bakang ho tsoa mali, liprotheine tse maling a hao li sebetsa li kopane ho etsa mali. Lehlaka le u thibela ho lahleheloa ke mali a mangata.

U na le mabaka a 'maloa a ho koalla maling a hao. Haeba ho na le lintlha tse haellang kapa tse nang le phoso, ho ka nka nako e telele ho feta e tloaelehileng hore mali a hoama. Maemong a mang, sena se baka tšollo ea mali e boima, e sa laoleheng. Teko ea PTT e lekola tšebetso ea lintlha tse itseng tsa coagulation. Tsena li kenyelletsa lintlha tse tsejoang e le factor VIII, factor IX, factor X1, le factor XII.

Mabitso a mang: promboplastin e sebelisitsoeng nako, aPTT, profil ea coagulation factor

E sebelisetsoa eng?

Teko ea PTT e sebelisetsoa ho:

• Lekola ts'ebetso ea lintlha tse ikhethileng tsa coagulation. Haeba efe kapa efe ea lintlha tsena e haella kapa e haelloa, ho ka bolela hore o na le lefu la ho tsoa mali. Mathata a ho tsoa mali ke sehlopha sa maemo a sa tloaelehang moo mali a sa koaleheng ka mokhoa o tloaelehileng. Boloetse bo tsebahalang haholo ba ho tsoa mali ke hemophilia.
• Fumana hore na ho na le lebaka le leng la ho tsoa mali a mangata kapa mathata a mang a hoama. Tsena li kenyelletsa mafu a itseng a itšireletsang mafung a etsang hore sesole sa 'mele se hlasele mabaka a ho koalla.
• Hlahloba batho ba noang heparin, mofuta oa moriana o thibelang ho hoama. Mathateng a mang a tsoang mali, mali a koala haholo, ho fapana le hore a koalehe haholo. Sena se ka baka tlhaselo ea pelo, stroke le maemo a mang a sokelang bophelo. Empa ho nka heparin e ngata haholo ho ka baka tšollo ea mali e feteletseng le e kotsi.

Hobaneng ha ke hloka tlhahlobo ea PTT?

U kanna oa hloka tlhahlobo ea PTT haeba u:

• Ho tsoa mali a mangata a sa hlaloseheng
• Roba habonolo
• E-ba le tšelo ea mali mothapong kapa mothapong
• E-ba le lefu la sebete, leo ka linako tse ling le ka bakang mathata ka ho koala mali
• Re tla fumana opereishene. Ho buoa ho ka baka tahlehelo ea mali, kahoo ho bohlokoa ho tseba hore na o na le bothata ba ho hoama.
• Ke bile le ho senyeheloa hangata
• Ba nka heparin

Ho etsahalang nakong ea tlhahlobo ea PTT?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea PTT.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Liphetho tsa hau tsa tlhahlobo ea PTT li tla bontša hore na ho nkile nako e kae hore mali a hao a koalehe. Liphetho hangata li fanoa joalo ka metsotsoana e mengata. Haeba liphetho tsa hau li bontša hore mali a hau a nkile nako e telele ho feta e tloaelehileng ho koala, ho ka bolela hore u na le:

• Lefu la ho tsoa mali, joalo ka hemophilia kapa von Willebrand. Lefu la Von Willebrand ke lona le atisang ho tsoa mali, empa hangata le baka matšoao a matla ho feta mathata a mang a tsoang mali.
• Lefu la sebete
• Lefu la Antiphospholipid antibody kapa lupus anticoagulant syndrome. Tsena ke mafu a ikemetseng a etsang hore sesole sa hau sa 'mele se hlasele mabaka a hau a coagulation.
• Khaello ea Vitamin K. Vithamine K e bapala karolo ea bohlokoa ho etseng li-coagulation factor.

Haeba u nka heparin, liphetho tsa hau li ka thusa ho bonts'a hore na u noa lethal dose e nepahetseng. Mohlomong o tla lekoa khafetsa ho etsa bonnete ba hore litekanyetso tsa hau li lula maemong a nepahetseng.

Haeba u fumanoa u na le lefu la ho tsoa mali, bua le mofani oa tlhokomelo ea bophelo. Le ha ho se na pheko bakeng sa mathata a mangata a tsoang mali, ho na le liphekolo tse teng tse ka thusang ho sebetsana le boemo ba hau.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea PTT?

Teko ea PTT hangata e laeloa hammoho le tlhahlobo e 'ngoe ea mali e bitsoang prothrombin time. Teko ea nako ea prothrombin ke tsela e 'ngoe ea ho metha bokhoni ba ho koala.

Litšupiso

1. Mokhatlo oa Amerika oa Hematology [Marang-rang]. Washington DC: Mokhatlo oa Amerika oa Hematology; c2018. Mathata a ho tsoa mali; [e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: http://www.hematology.org/Patients/Bleeding.aspx
2. Litsi tsa Tlhokomelo le Thibelo ea Maloetse [Internet]. Atlanta: Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Haemophilia: Ho lemoha; [e ntlafalitsoeng ka 2011 Sep 13; e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.cdc.gov/ncbddd/hemophilia/diagnosis.html
3. Hinkle J, Cheever K. Brunner & Suddarth's Handbook ea Liteko tsa Laboraro le Tlhatlhobo. 2nd Ed, mosa. Philadelphia: Wolters Kluwer Bophelo, Lippincott Williams & Wilkins; c2014. Nako ea Karolo ea Thromboplastin (PTT); leq. EA-400.
4. Setsi sa Indiana Hemophilia & Thrombosis Center [Marang-rang]. Indianapolis: Indiana Hemophilia & Thrombosis Center Inc .; c2011–2012. Mathata a ho tsoa mali; [e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: http://www.ihtc.org/patient/blood-disorders/bleeding-disorders
5. Bophelo ba Bana ho tsoa Nemours [Marang-rang]. Jacksonville (FL): Motheo oa Nemours; c1995–2018. Teko ea Mali: Karolo ea Thromboplastin Nako (PTT); [e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://kidshealth.org/en/parents/test-ptt.html?ref=search&WT.ac=msh-p-dtop-en-search-cl
6. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Karolo ea Thromboplastin Nako; [e ntlafalitsoeng 2018 Mar 27; e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/partial-thromboplastin-time-ptt-aptt
7. Mayo Clinic: Mayo Medical Laboratories [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1995–2018. Boitsebiso ba teko: ATPTT: E sebelisitsoe Nako e Ikhethileng ea Thromboplastin (APTT), Plasma: Clinical and Interpretive; [e qotsitsoeng 2018 Aug 26]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/40935
8. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali; [e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. Riley Children's Health [Marang-rang]. Indianapolis: Sepetlele sa Riley sa Bana Univesithing ea Indiana Health; c2018. Mathata a Coagulation; [e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.rileychildrens.org/health-info/coagulation-disorders
10. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida; c2018. Nako ea karoloana ea thromboplastin (PTT): Kakaretso; [e ntlafalitsoeng 2018 Aug 26; e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/partial-thromboplastin-time-ptt
11. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2018. Health Encyclopedia: Nako ea Phallo ea Karolo e Khethiloeng ea Thromboplastin; [e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=aptt
12. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2018. Tlhahisoleseling ea Bophelo: Karolo e itseng ea Thromboplastin Nako: Liphetho; [e ntlafalitsoeng 2017 Oct 5; e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 8]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/partial-thromboplastin-time/hw203152.html#hw203179
13. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2018. Tlhahisoleseling ea Bophelo: Karolo e itseng ea Thromboplastin Nako: Tlhatlhobo ea liteko; [e ntlafalitsoeng 2017 Oct 5; e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/partial-thromboplastin-time/hw203152.html
14. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2018. Tlhahisoleseling ea Bophelo: Karolo e itseng ea Thromboplastin Nako: Hobaneng ha e etsoa; [e ntlafalitsoeng 2017 Oct 5; e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/partial-thromboplastin-time/hw203152.html#hw203160
15. WFH: Mokhatlo oa Lefatše oa Hemophilia [Inthanete]. Montreal Quebec, Canada: Mokhatlo oa Lefatše oa Hemophilia; c2018. Lefu la von Willebrand (VWD) ke eng; [e ntlafalitsoeng ka 2018 Phuptjane; e qotsitsoeng 2018 Aug 26]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.wfh.org/en/page.aspx?pid=673

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.