Teko ea Lactate Dehydrogenase (LDH)

Litaba

• Teko ea lactate dehydrogenase (LDH) ke eng?
• E sebelisetsoa eng?
• Hobaneng ke hloka tlhahlobo ea LDH?
• Ho etsahalang nakong ea tlhahlobo ea LDH?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Litšupiso

Teko ea lactate dehydrogenase (LDH) ke eng?

Teko ena e lekanya boemo ba lactate dehydrogenase (LDH), e tsejoang hape e le lactic acid dehydrogenase, maling a hao kapa ka linako tse ling maro a mang a 'mele. LDH ke mofuta oa protheine, e tsejoang e le enzyme. LDH e bapala karolo ea bohlokoa ho etseng matla a 'mele oa hau. E fumanoa hoo e batlang e le lisele tsohle tsa 'mele, ho kenyelletsa tse maling, pelong, liphio, bokong le matšoafong.

Ha lisele tsena li senyehile, li ntša LDH maling kapa maling a mang a 'mele. Haeba mali a LDH kapa mokelikeli oa hau o phahame, ho ka bolela hore lisele tse itseng 'meleng oa hau li sentsoe ke mafu kapa kotsi.

Mabitso a mang: Teko ea LD, lactic dehydrogenase, lactic acid dehydrogenase

E sebelisetsoa eng?

Hangata teko ea LDH e sebelisoa ho:

• Fumana hore na o na le tšenyo ea lisele
• Hlahloba mathata a bakang tšenyo ea lisele. Tsena li kenyelletsa khaello ea mali, lefu la sebete, lefu la matšoafo le mefuta e meng ea tšoaetso.
• Hlahloba chemotherapy bakeng sa mofetše oa mefuta e meng. Teko e kanna ea bontša haeba kalafo ea sebetsa.

Hobaneng ke hloka tlhahlobo ea LDH?

U kanna oa hloka tlhahlobo ena haeba liteko tse ling le / kapa matšoao a hau a bontša hore u na le tšenyo ea lisele kapa lefu. Matšoao a tla fapana ho latela mofuta oa tšenyo ea lisele tseo u nang le tsona.

U kanna ua hloka tlhahlobo ea LDH haeba hona joale u alafshoa ke mofets'e.

Ho etsahalang nakong ea tlhahlobo ea LDH?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

LDH ka linako tse ling e lekanngoa le maro a mang a 'mele, ho kenyeletsoa le maro a mokokotlong, matšoafo kapa mpa. Haeba o na le e 'ngoe ea liteko tsena, mofani oa tlhokomelo ea bophelo o tla fana ka tlhaiso-leseling e batsi ka ts'ebetso ena.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea mali ea LDH.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Ho phahama ho feta maemo a tloaelehileng a LDH hangata ho bolela hore o na le mofuta o itseng oa tšenyo ea lisele kapa lefu. Mathata a bakang maemo a phahameng a LDH a kenyelletsa:

• Khaello ea mali
• Lefu la liphio
• Lefu la sebete
• Kotsi ea mesifa
• Lefu la pelo
• Pancreatitis
• Matšoao, ho kenyelletsa meningitis, encephalitis, le tšoaetso ea mononucleosis (mono)
• Mefuta e meng ea mofets'e, ho kenyeletsoa lymphoma le kankere ea mali. Tekanyo e phahameng ho feta e tloaelehileng ea LDH e kanna ea bolela hore kalafo ea mofetše ha e sebetse.

Le ha tlhahlobo e ka bonts'a haeba u na le ts'enyo ea lisele kapa mafu, ha e bontše moo tšenyo e leng teng. Haeba liphetho tsa hau li bonts'itse holimo ho feta maemo a tloaelehileng a LDH, mofani oa hau a ka hloka ho odara liteko tse ling ho etsa tlhahlobo E 'ngoe ea liteko tsena e ka ba tlhahlobo ea LDH isoenzyme. Teko ea LDH isoenzyme e lekanya mefuta e fapaneng ea LDH. E ka thusa mofani oa hau ho tseba ka sebaka, mofuta le boima ba tšenyo ea lisele.

Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Litšupiso

1. Henry BM, Aggarwal G, Wong J, Benoit S, Vikse J, Plebani M, Lippi G. Lactate dehydrogenase maemo a noha lefu la coronavirus 2019 (COVID-19) boima le lefu: Tlhatlhobo e kopaneng. Am J Emerg Med [Inthanete]. 2020 Mots'eanong 27 [e qotsitsoeng ka 2020 Aug 2]; 38 (9): 1722-1726. E fumaneha ho tsoa ho: https://www.ajemjournal.com/article/S0735-6757(20)30436-8/fulltext
2. Bophelo ba Bana ho tsoa Nemours [Marang-rang]. Jacksonville (FL): Motheo oa Nemours; c1995–2019. Teko ea Mali: Lactate Dehydrogenase; [e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://kidshealth.org/en/parents/test-ldh.html
3. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Mokelikeli oa Cerebrospinal (CSF); [e ntlafalitsoeng 2017 Nov 30; e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/glossary/cerebrospinal
4. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Lactate Dehydrogenase (LD); [e nchafalitsoeng 2018 Dec 20; e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/lactate-dehydrogenase-ld
5. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Meningitis le Encephalitis; [e ntlafalitsoeng 2018 Feb 2; e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/conditions/meningitis-and-encephalitis
6. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Tlhahlobo ea metsi a Peritoneal; [e ntlafalitsoeng 2019 ka la 13 Mots'eanong; e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/peritoneal-fluid-analysis
7. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Tlhatlhobo ea Mokelikeli oa Pleural; [e ntlafalitsoeng 2019 ka la 13 Mots'eanong; e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/pleural-fluid-analysis
8. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali; [e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2019. Health Encyclopedia: Lactic Acid Dehydrogenase (Mali); [e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=lactic_acid_dehydrogenase_blood
10. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2019. Teko ea Lactate dehydrogenase: Kakaretso; [e ntlafalitsoeng 2019 Jul 1; e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/lactate-dehydrogenase-test
11. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2019. Lactic Acid Dehydrogenase (LDH): Tlhatlhobo ea Tlhatlhobo; [e ntlafalitsoeng 2018 Jun 25; e qotsitsoeng ka la 1 Phupu 1]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/testdetail/lactic-dehydrogenase-ldh/tv6985.html#tv6986

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.