Hyperparathyroidism ke eng le hore na o ka e phekola joang

Litaba

• Matšoao a mantlha
• Tsela ea ho hlahloba
• Kalafo e etsoa joang

Hyperparathyroidism ke lefu le bakang tlhahiso e fetelletseng ea hormone ea PTH, e lokolloang ke litšoelesa tsa parathyroid, tse molaleng kamora qoqotho.

Hormone PTH e thusa ho boloka maemo a khalsiamo maling 'me, bakeng sa seo, litlamorao tsa eona tsa mantlha li kenyelletsa ho khutlisetsoa ha khalsiamo liphio, ho monya khalsiamo e tsoang lijong ka maleng, hammoho le ho tlosa khalsiamo e bolokiloeng masapong ho lokolla ho kena mading.

Hyperparathyroidism e ka hlaha ka mekhoa e meraro:

• Matšoao a mantlha a hyperparathyroidism: ho etsahala ha lefu la li-parathyroids ka boeona le baka hypersecretion ea hormone PTH, haholo-holo ka lebaka la adenoma kapa hyperplasia ea litšoelesa tsena;
• Matšoao a bobeli a hyperparathyroidism: e hlaha ka lebaka la pherekano ea metabolism ea 'mele, e hlohlelletsang litšoelesa tsa parathyroid, haholoholo ka lebaka la ho hloleha ha liphio, mme e bakang maemo a fokotsehileng a calcium le phosphorus ho ajeng;
• Thuto e phahameng ea hyperparathyroidism: ha e fumanehe hangata, e tšoauoa ha litšoelesa tsa parathyroid li qala ho ntša PTH e le 'ngoe,' me li ka hlaha kamora nako e itseng ea hyperparathyroidism ea bobeli.

Ha e tsejoa, hyperparathyroidism e hloka ho phekoloa kapele, hobane e ka ba le litlamorao tse mpe, joalo ka ho fokolisa masapo, ho eketsa menyetla ea ho robeha. Ntle le moo, khalsiamo e fetelletseng maling le eona e ka baka liphetoho ts'ebetsong ea mesifa, majoe a liphio, khatello e phahameng ea mali le mathata a mang a pelo.

Lefu lena lea phekoleha ha ho etsoa opereishene ho tlosa tšoelesa, leha ho le joalo, pele ho moo, ho ka bontšoa litlhare tse ka sebelisoang ho laola matšoao.

Matšoao a mantlha

Tse ling tsa matšoao le matšoao a hyperparathyroidism ke:

• Lesapo le fokolang le kotsing e kholo ea ho robeha;
• Bofokoli ba mesifa;
• Ntlafatso ea majoe a liphio;
• Takatso e eketsehileng ea ho ntša metsi;
• Kamehla bohloko ka mpeng;
• Mokhathala o feteletseng;
• Nts'etsopele ea ho hloleha ha renal kapa pancreatitis;
• Ho nyekeloa, ho hlatsa le ho lahleheloa ke takatso ea lijo.

Hyperparathyroidism ha se hangata e bakang matšoao, haholo maemong a pele, ka hona ho tloaelehile hore lefu lena le tsejoe litekong tse tloaelehileng tsa mali, tse bonts'ang liphetoho maemong a khalsiamo ea mali.

Tsela ea ho hlahloba

Ho fumanoa ha hyperparathyroidism ho etsoa ka tekanyo ea hormone PTH, e eketsoang mefuteng eohle ea lefu lena. Ebe, endocrinologist e tla laela liteko tse ling tse thusang ho tseba sesosa sa bothata, joalo ka tekanyetso ea calcium, e phahameng ho hyperparathyroidism ea mantlha mme e fokotsoe sehlopheng sa bobeli, ntle le liteko tse kang calcium le phosphorus ka morong, mohlala.

Litlhahlobo tsa radiographic le tsona li ka thusa ho khetholla lefu lena, kaha le bonts'a masapo a nang le demineralization le lefu la masapo. Maemong a tsoetseng pele haholo, tlhahlobo ena e ka bonts'a sebopeho sa ho epolloa le ho ata ha lisele le lijana masapong, tse tsejoang e le "hlahala e sootho".

Ntle le moo, litlhahlobo tsa setšoantšo sa molala, tse nang le ultrasound, scintigraphy kapa imaging resonance imaging, ka mohlala, li ka thusa ho khetholla liphetoho litšoelesa tsa parathyroid.

Kalafo e etsoa joang

Mohato oa pele oa ho phekola hyperparathyroidism ea mantlha ke tokiso ea maemo a khalsiamo, ao, haeba a fetotsoe haholo, e ka bang sesosa se ka sehloohong sa matšoao. Bakeng sa sena, ho na le likhetho tse fapaneng, tse kenyelletsang phetoho ea lihormone, e entsoeng haholo ho basali kamora ho khaotsa ho ilela khoeli, kaha ho nkeloa sebaka ke lihormone tse ling ho thusa ho boloka maemo a calcium masapong. Lithethefatsi tsa Bisphosphonate, ka lehlakoreng le leng, le tsona li thusa ho eketsa ho beoa ha calcium masapong, ho fokotsa calcium ea mahala maling. Hlahloba lisosa tse ling tsa khalsiamo e ngata maling le mokhoa oa ho e phekola.

Ho buoa ho ka bonts'oa hape maemong a hyperparathyroidism ea mantlha, kaha e tlosa litšoelesa tse amehileng, e folisa lefu lena. Leha ho le joalo, e na le likotsi tse ling joalo ka tšenyo ea methapo e laolang methapo ea lentsoe kapa phokotso e tšoaeang ea maemo a calcium.

Tabeng ea hyperparathyroidism ea bobeli, ho hlokahala hore ho etsoe leihlo le kalafo e nepahetseng ea ho hloleha ha renal, ho nkeloa sebaka ke vithamine D le calcium, tse fokotsitsoeng. Lipheko tsa calcimimetic li na le phello e ts'oanang le calcium, e etsang hore litšoelesa li hlahise lihormone tse fokolang. Mohlala oa litlhare tsena ke cinacalcete.