Heinz Bodies ke eng?

Litaba

• Mele ea Heinz ke eng?
• Mabapi le hemoglobin
• Mabapi le 'mele ea Heinz
• Mathata a amanang le mali
• Ke eng e bakang 'mele ea Heinz?
• Na ho na le matšoao a amanang le 'mele ea Heinz?
• Thalassemia
• Phokolo ea mali ea hemolytic
• Khaello ea G6PD
• Mele ea Heinz e phekoloa joang?
• Phapang ke efe lipakeng tsa 'mele ea Heinz le' mele ea Howell-Jolly?
• Litsela tsa bohlokoa tsa ho nka

Litopo tsa Heinz, tse ileng tsa sibolloa ka lekhetlo la pele ke Dr. Robert Heinz ka 1890 hape li tsejoa e le 'mele ea Heinz-Erlich, ke maqhubu a hemoglobin e senyehileng e liseleng tse khubelu tsa mali. Ha hemoglobin e senyeha, e ka etsa hore lisele tse khubelu tsa mali li emise ho sebetsa hantle.

Melemo ea Heinz e amahanngoa le liphatsa tsa lefutso le tikoloho mme e hokahane le maemo a itseng a mali, joalo ka haemolytic anemia.

Sehloohong sena, re tla hlahloba lisosa, matšoao le likhetho tsa kalafo bakeng sa maemo a amanang le 'mele ea Heinz.

Mele ea Heinz ke eng?

Mabapi le hemoglobin

Lisele tsohle tse khubelu tsa mali, tse tsejoang hape e le li-erythrocyte, li na le protheine e bitsoang hemoglobin. Hemoglobin e ikarabella bakeng sa ho tsamaisa oksijene kahare ho lisele tse khubelu tsa mali ho potoloha le 'mele.

Ha hemoglobin e pepesetsoa ke metsoako e chefo, e ka "senyeha" kapa ea senyeha. Liprotheine tsa Denatured tseo sebopeho sa tsona li senyehileng li ke keng tsa sebetsa joalo ka liprotheine tse tloaelehileng mme li ka bapala karolo ea kholo ea mafu a itseng.

Mabapi le 'mele ea Heinz

Hemoglobin e kentsoeng kahare ho lisele tse khubelu tsa mali e bitsoa 'mele ea Heinz. Ha li shejoa ka tlas'a microscope nakong ea tlhahlobo ea mali, li bonahala e le makumane a sa tloaelehang a tsoang liseleng tse khubelu tsa mali.

Mathata a amanang le mali

Le ha 'mele ea Heinz e ithutiloe bathong le liphoofolong, bathong e amahanngoa le mathata a fokolang a lisele tse khubelu tsa mali, ho kenyelletsa:

• thalassemia
• haemolytic khaello ea mali
• khaello ea tsoekere-6-phosphate dehydrogenase (G6PD)

Hemolytic anemia ke boemo bo tloaelehileng haholo bo bakoang ke 'mele ea Heinz, empa ha se bohle ba nang le' mele ea Heinz ba tla e hlahisa. Maemo a mang a boletsoeng kaholimo a ka etsa hore 'mele ea Heinz e hlahe liphethong tsa liteko tsa lab, leha e se na phokolo ea mali ea hemolytic.

Ke eng e bakang 'mele ea Heinz?

Melemo ea Heinz e amahanngoa le liphatsa tsa lefutso le tikoloho. Ka mohlala, 'mele ea Heinz ka masea e ka bontša mathata a tsoalo ea lisele tse khubelu tsa mali. Melemo ea Heinz le eona e ka bakoa ke ho pepesehela lintho tse itseng tse chefo.

Mathoasong a 1984, mokuli o ile a ba le lefu la phokolo ea mali ea Heinz-body hemolytic kamora ho noa oli e nang le peterole e nang le cresol.

Lintho tse ling tse ka bang le chefo tse ka bakang sebopeho sa 'mele oa Heinz kamora ho pepeseha kapa ho kenella li kenyelletsa:

• makhasi a maple (haholo-holo liphoofolong)
• eiee e hlaha (haholo-holo liphoofolong)
• lithethefatsi tse ling, ho kenyelletsa le vithamine K ea maiketsetso, phenothiazines, methylene blue le tse ling
• dae tse itseng tse sebelisetsoang maleiri
• lik'hemik'hale tse sebelisetsoang ho etsa li-mothball

Na ho na le matšoao a amanang le 'mele ea Heinz?

Le ha ho sena matšoao a ikhethang bakeng sa 'mele ea Heinz, ho na le matšoao a amanang le lisosa tsa mantlha mme maemong a mang, ho pepeseha hoa mantlha.

Thalassemia

Matšoao a thalassemia a kenyeletsa:

• kholo e liehang
• litaba tsa nts'etsopele
• ho holofala ha masapo
• mokgathala
• jaundice
• moroto o lefifi

Phokolo ea mali ea hemolytic

Matšoao a phokolo ea mali ea hemolytic a kenyeletsa:

• letlalo le boreleli hofeta tloaelo
• bofokoli
• hlooho e bobebe
• ho otla ha pelo
• ho holisa spleen kapa sebete

Khaello ea G6PD

Matšoao a khaello ea G6PD a kenyeletsa:

• letlalo le boreleli hofeta tloaelo
• ho tsekela
• mokgathala
• ho hema ka thata
• keketseho ea lebelo la pelo
• jaundice

Leha ho pepesehela limela tse chefo tse hlaha e le sesosa sa 'mele ea Heinz haholo liphoofolong, meriana e meng e ka baka tlhahiso ea' mele ea Heinz bathong.

Meriana e ka bakang 'mele ea Heinz e sebelisoa ho phekola maemo a fapaneng, joalo ka psychosis le methemoglobinemia. Ho kanna ha se be le matšoao a kantle a boteng ba 'mele ea Heinz maemong ana. Ho e-na le hoo, ho ka etsahala hore ba fumanoe nakong ea tlhahlobo ea mali e tloaelehileng.

Mele ea Heinz e phekoloa joang?

Khetho ea kalafo bakeng sa khaello ea mali ea hemolytic, thalassemia le G6PD ea tšoana. Ho latela boima ba boemo bona, li kanna tsa kenyelletsa:

• meriana
• litlatsetso
• Phekolo ea IV
• phekolo ea oksijene
• litšelo tsa mali
• ho tlosoa ha spleen, maemong a boima

Bakeng sa 'mele ea Heinz e bakiloeng ke ho pepesetsoa meriana e itseng, ngaka ea hau e kanna ea khetha ho sebelisa meriana e meng bakeng sa maemo a hau.

Maemong a mang, likhetho tse ling tsa meriana li kanna tsa se fumanehe. Tabeng ena, o ka buisana ka tsela e molemohali ea ho thibela nts'etsopele ea phokolo ea mali ea hemolytic.

Phapang ke efe lipakeng tsa 'mele ea Heinz le' mele ea Howell-Jolly?

Le ha 'mele ka bobeli e ka fumanoa lisele tse khubelu tsa mali,' mele ea Heinz ha e tšoane le 'mele ea Howell-Jolly.

Ha lisele tse khubelu tsa mali li qetile ho hola mokong oa masapo, li ka kenella ho potoloha ho qala ho fana ka oksijene 'meleng. Ha li ntse li qala ho ajoa, li lahla khubu ea tsona.

Leha ho le joalo, maemong a mang, mokokotlo o kanna oa se ke oa lahloa ka botlalo. Nakong ena, spleen e kenella le ho tlosa masala a setseng.

Mele ea Howell-Jolly ke lebitso la masala a DNA a setseng ka har'a lisele tse khubelu tsa mali tse holileng. Boteng ba 'mele ea Howell-Jolly hangata bo supa hore spleen ha e etse mosebetsi oa eona kapa ha e eo.

Maemong a mang, 'mele ea Howell-Jolly e kanna ea amahanngoa le phokolo ea mali e megaloblastic.

Litsela tsa bohlokoa tsa ho nka

Boteng ba 'mele ea Heinz tlhahlobisong ea mali e bontša tšenyo ea mali ho hemoglobin e liseleng tse khubelu tsa mali.

Maemo a amanang le 'mele ea Heinz a kenyelletsa maemo a itseng a mali, joalo ka thalassemia kapa hemolytic anemia. Melemo ea Heinz e kanna ea amahanngoa le ho kenella kapa ho pepesehela lintho tse chefo.

Kalafo bakeng sa 'mele ea Heinz e kenyelletsa ho fumana le ho phekola sesosa sa ona.

Haeba ngaka ea hau e hlokometse 'mele ea Heinz tlhahlobong ea hau ea mali, o ka sebetsa le bona ho fumana tlhahlobo le kalafo ea semolao bakeng sa maemo afe kapa afe.