Teko ea Haptoglobin (HP)

Litaba

• Teko ea haptoglobin (HP) ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea haptoglobin?
• Ho etsahalang nakong ea tlhahlobo ea haptoglobin?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo ea haptoglobin?
• Liphetho li bolelang?
• Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea haptoglobin?
• Litšupiso

Teko ea haptoglobin (HP) ke eng?

Teko ena e lekanya boholo ba haptoglobin maling. Haptoglobin ke protheine e entsoeng ke sebete sa hau. E khomarela mofuta o itseng oa hemoglobin. Hemoglobin ke protheine e liseleng tsa hao tse khubelu tsa mali tse tsamaisang oksijene matšoafong a hao ho ea 'meleng oohle. Boholo ba hemoglobin bo fumaneha ka har'a lisele tse khubelu tsa mali, empa tse nyane li potoloha maling. Haptoglobin e tlamahanya le hemoglobin e maling. Hammoho, liprotheine tse peli li tsejoa e le moetso oa haptoglobin-hemoglobin. Mohaho ona o tlosoa kapele maling ebe o tlosoa 'meleng ke sebete sa hao.

Ha lisele tse khubelu tsa mali li senyehile, li ntša hemoglobin e eketsehileng maling. Seo se bolela hore moetso oa haptoglobin-hemoglobin o tla tlosoa 'meleng. Haptoglobin e ka tloha 'meleng kapele ho feta kamoo sebete se ka e etsang ka teng. Sena se etsa hore maqhubu a hau a mali a haptoglobin a theohe. Haeba maemo a hau a haptoglobin a le tlase haholo, e kanna ea ba sesupo sa lefu la lisele tse khubelu tsa mali, joalo ka phokolo ea mali.

Mabitso a mang: protheine e tlamang hemoglobin, HPT, Hp

E sebelisetsoa eng?

Hangata ho sebelisoa teko ea haptoglobin ho fumana lefu la phokolo ea mali ea haemolytic. Hemolytic anemia ke boloetse bo etsahalang ha lisele tsa hau tse khubelu tsa mali li senngoa kapele ho feta kamoo li ka nkeloang sebaka. Teko ena e kanna ea sebelisoa ho bona hore na mofuta o mong oa phokolo ea mali kapa lefu le leng la mali le baka matšoao a hau.

Hobaneng ha ke hloka tlhahlobo ea haptoglobin?

U kanna oa hloka teko ena haeba u na le matšoao a phokolo ea mali. Tsena li kenyelletsa:

• Mokhathala
• Letlalo le putswa
• Phefumoloho e khutšoanyane
• Ho otla ha pelo ka potlako
• Jaundice, boemo bo etsang hore letlalo le mahlo a hao a be bosehla
• Moroto o mmala o lefifi

U kanna ua hloka teko ena haeba u kile ua tšeloa mali. Teko e kanna ea etsoa ka tlhahlobo e ngoe e bitsoang anti-globulin ka kotloloho. Liphello tsa liteko tsena li ka bontša haeba u bile le karabelo e mpe tšelong.

Ho etsahalang nakong ea tlhahlobo ea haptoglobin?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea haptoglobin.

Na ho na le likotsi tsa tlhahlobo ea haptoglobin?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Haeba liphetho tsa hau li bonts'a hore maemo a hau a haptoglobin a tlase ho feta a tloaelehileng, ho ka bolela hore o na le e 'ngoe ea maemo a latelang:

• Phokolo ea mali ea hemolytic
• Lefu la sebete
• Karabelo ea tšelo ea mali

Mofani oa hao oa tlhokomelo ea bophelo a ka laela liteko tse ling tsa mali ho thusa ho etsa tlhahlobo. Tsena li kenyelletsa:

• Palo ea Reticulocyte
• Teko ea Hemoglobin
• Teko ea Hematocrit
• Teko ea Lactate Dehydrogenase
• Mali tlotsa
• Palo e Felletseng ea Mali

Liteko tsena li ka etsoa ka nako e ts'oanang kapa kamora tlhahlobo ea hau ea haptoglobin.

Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea haptoglobin?

Maemo a phahameng a haptoglobin e kanna ea ba sesupo sa lefu la ho ruruha. Maloetse a bakoang ke ho ruruha ke mathata a sesole sa 'mele a ka bakang mathata a tebileng a bophelo bo botle. Empa tlhahlobo ea haptoglobin ha e sebelisoe hangata ho hlahloba kapa ho lekola maemo a amanang le maemo a phahameng a haptoglobin.

Litšupiso

1. Mokhatlo oa Amerika oa Hematology [Marang-rang]. Washington DC: Mokhatlo oa Amerika oa Hematology; c2020. Khaello ea mali; [e qotsitsoeng ka 2020 Mar 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: http://www.hematology.org/Patients/Anemia
2. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001--2020. Haptoglobin; [e ntlafalitsoeng 2019 Sep 23; e qotsitsoeng ka 2020 Mar 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/haptoglobin
3. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001--2020. Jaundice; [e ntlafalitsoeng 2019 Oct 30; e qotsitsoeng ka 2020 Mar 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/conditions/jaundice
4. Maine Health [Inthanete]. Portland (ME): Maine Health; c2020. Boloetse ba ho ruruha / Ho ruruha; [e qotsitsoeng ka 2020 Mar 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://mainehealth.org/services/autoimmune-diseases-rheumatology/infigueatory-diseases
5. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali; [e qotsitsoeng ka 2020 Mar 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
6. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Khaello ea mali Hemolytic; [e qotsitsoeng ka 2020 Mar 4]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/hemolytic-anemia
7. Shih AW, McFarlane A, Verhovsek M. Haptoglobin tlhahlobo ea hemolysis: tekanyo le tlhaloso. Am J Hematol [Inthanete]. 2014 Mphalane [e qotsitsoeng ka 2020 Mar 4]; 89 (4): 443-7. E fumaneha ho tsoa ho: https://www.ncbi.nlm.nih.gov/pubmed/24809098
8. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2020. Teko ea mali ea Haptoglobin: Kakaretso; [e nchafalitsoeng 2020 Mar 4; e qotsitsoeng ka 2020 Mar 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/winaoglobin-blood-test
9. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2020. Health Encyclopedia: Haptoglobin; [e qotsitsoeng ka 2020 Mar 4]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid= Bapoglobin

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.