Sengoli: Laura McKinney
Letsatsi La Creation: 1 April 2021
Ntlafatsa Letsatsi: 17 November 2024
Anonim
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Litaba

Ho ntšoa peo ea morara (GSE) ke tlatsetso ea lijo tse entsoeng ka ho tlosa, ho omisa le ho silila peo e monate ea morara.

Peo ea morara e na le li-antioxidants tse ngata, ho kenyelletsa phenolic acid, anthocyanins, flavonoids le oligomeric proanthocyanidin complexes (OPCs).

Ebile, GSE ke o mong oa mehloli e tsebahalang haholo ea proanthocyanidins (,).

Ka lebaka la lihlahisoa tsa eona tse phahameng tsa antioxidant, GSE e ka thusa ho thibela maloetse le ho itšireletsa khahlanong le khatello ea mali, tšenyo ea lisele le ho ruruha ().

Hlokomela hore tlhotla ea peo ea morara le peo ea litholoana tsa morara li rekisoa ka bobeli e le li-supplement le ho khutsufatsoa ke lebitso la lebitso la GSE. Sengoliloeng sena se tšohla tlhotla ea peo ea morara.

Mona ke melemo e 10 ea bophelo bo botle ba ho ntša peo ea morara, tsohle li ipapisitse le saense.

1. E ka fokotsa khatello ea mali

Liphuputso tse 'maloa li batlile litlamorao tsa GSE ka khatello e phahameng ea mali.


Tlhahlobo ea lithuto tse 16 ho batho ba 810 ba nang le khatello e phahameng ea mali kapa kotsi e phahameng ea eona e fumane hore ho nka 100-2,000 mg ea GSE letsatsi le letsatsi ho fokolitse khatello ea mali ea systolic le diastolic haholo (palo e holimo le tlase) ka karolelano ea 6.08 mmHg le 2.8 mmHg, ka ho latellana.

Ba ka tlase ho lilemo tse 50 ba nang le botenya kapa bokuli bo amanang le ts'oaetso ba bonts'itse lintlafatso tse kholo.

Liphetho tse ts'episang ka ho fetisisa li tsoa litekanyetsong tse tlase tsa 100-800 mg letsatsi ka leng bakeng sa libeke tsa 8-16, ho fapana le tekanyetso e le 'ngoe ea 800 mg kapa ho feta ().

Phuputso e 'ngoe ho batho ba baholo ba 29 ba nang le khatello e phahameng ea mali e fumane hore ho nka 300 mg ea GSE letsatsi le letsatsi ho theola khatello ea mali ea systolic ka 5.6% le khatello ea mali ea diastolic ka 4.7% kamora libeke tse 6 ().

Kakaretso GSE e ka thusa ho fokotsa khatello ea mali, haholo ho bacha ho isa lilemong tsa bohareng le ba nang le boima bo feteletseng.

2. E ka ntlafatsa phallo ea mali

Boithuto bo bong bo bontša hore GSE e ka ntlafatsa phallo ea mali.

Phuputsong ea libeke tse 8 ho basali ba 17 ba postmenopausal ba phetseng hantle, ho nka 400 mg ea GSE ho bile le litlamorao tsa ho fokotsa mali, ho ka fokotsang kotsi ea maqeba a mali ().


Phuputso e eketsehileng ho basali ba bacha ba 8 ba phetseng hantle e hlahlobile litlamorao tsa tekanyetso e le 'ngoe ea 400-mg ea proanthocyanidin e tsoang GSE hanghang e lateloang ke lihora tse 6 tsa ho lula. E bontšitsoe ho fokotsa ho ruruha ha leoto le edema ka 70%, ha e bapisoa le ho se nke GSE.

Thutong e ts'oanang, basali ba bang ba bacha ba 8 ba phetseng hantle ba nkileng letsatsi le leng le le leng 133-mg ea li-proanthocyanidins tse tsoang GSE matsatsi a 14 ba bile le ho ruruha ha leoto ka tlase ho 40% kamora ho lula lihora tse 6).

Kakaretso GSE e bonts'itsoe ho ntlafatsa phallo ea mali le ho fokotsa kotsi ea ho koala mali, e ka thusang ba nang le mathata a ho potoloha ha mali.

3. E ka fokotsa tšenyo ea oxidative

Lebelo le phahameng la mali la LDL (mpe) cholesterol ke kotsi e tsebahalang ea lefu la pelo.

Ho tšeloa ha k'holeseterole ea LDL ho eketsa kotsi ena haholo mme ho bapala karolo ea bohlokoa ho atherosclerosis, kapa lehloe le nang le mafura methapong ea hau ().

Lisebelisoa tsa GSE li fumanoe li fokotsa phokolo ea LDL e bakiloeng ke lijo tse nang le mafura a mangata lithutong tse 'maloa tsa liphoofolo (,,).


Phuputso e 'ngoe ho batho e bonts'a sephetho se tšoanang (,).

Ha batho ba 8 ba phetseng hantle ba ja lijo tse nang le mafura a mangata, ho nka 300 mg ea GSE ho thibela ho kenella ha mafura maling, ha ho bapisoa le keketseho ea 150% e bonoang ho ba sa nkeng GSE ().

Phuputsong e 'ngoe, batho ba baholo ba 61 ba phetseng hantle ba bone phokotso ea 13.9% ho LDL e nang le oxidized kamora ho nka 400 mg ea GSE. Leha ho le joalo, phuputso e ts'oanang e ne e sa khone ho pheta liphetho tsena (,).

Ntle le moo, phuputso ho batho ba 87 ba neng ba etsoa opereishene ea pelo e fumane hore ho nka 400 mg ea GSE letsatsi pele ho ts'ebetso e ntse e fokotsa khatello ea maikutlo ea oxidative. Ka hona, GSE e kanna ea sireletsoa khahlano le tšenyo e ngoe ea pelo ().

Kakaretso GSE e ka thusa ho fokotsa menyetla ea ho tšoaroa ke lefu la pelo ka ho thibela ho kenella ha k'holeseterole ea LDL (e mpe) le ho fokotsa ts'oaetso ho lisele tsa pelo nakong ea khatello ea maikutlo.

4. E ka ntlafatsa maemo a collagen le matla a masapo

Ho eketsa tšebeliso ea flavonoid ho ka ntlafatsa collagen synthesis le sebopeho sa masapo.

Joaloka mohloli o ruileng oa li-flavonoids, GSE e ka thusa ho eketsa masapo le matla a hau.

Ebile, lithuto tsa liphoofolo li fumane hore ho eketsa GSE khalsiamo e tlase, e tloaelehileng kapa e phahameng ea khalsiamo ho ka eketsa masapo, masapo a diminerale le matla a masapo (,).

Ramatiki ea ramatiki ke boemo bo ikemetseng bo hlahisang ho ruruha ho matla le ho senyeha ha masapo le manonyeletso.

Liphuputso tsa liphoofolo li bonts'itse hore GSE e kanna ea hatella tšenyo ea masapo ho ramatiki ea ho itšireletsa mafung (,,).

GSE e boetse e fokolitse bohloko haholo, bony spurs, le tšenyo e kopaneng ea litoeba tsa lefu la masapo, ho ntlafatsa maemo a collagen le ho fokotsa tahlehelo ea lefufuru ().

Leha ho na le litholoana tse ts'episang ho tsoa lipatlisisong tsa liphoofolo, lithuto tsa batho lia haella.

Kakaretso Liphuputso tsa liphoofolo li bonts'a sephetho se ts'episang mabapi le bokhoni ba GSE ba ho thusa ho phekola maemo a ramatiki le ho khothaletsa bophelo bo botle ba collagen. Leha ho le joalo, lipatlisiso tsa batho lia haella.

5. E tšehetsa boko ba hau ha bo ntse bo tsofala

Motsoako oa Flavonoids oa antioxidant le anti-inflammatory properties ho nahanoa hore o liehisa kapa ho fokotsa ho qala ha mafu a methapo ea pelo joalo ka lefu la Alzheimer's ().

E 'ngoe ea likarolo tsa GSE ke gallic acid, eo lithuto tsa liphoofolo le tsa labor li bonts'itseng li ka thibela sebopeho sa likhoele ka li-peptide tsa beta-amyloid ().

Lihlopha tsa liprotheine tsa beta-amyloid bokong li tšoaea lefu la Alzheimer's ().

Liphuputso tsa liphoofolo li fumane hore GSE e ka thibela ho lahleheloa ke mohopolo, ea ntlafatsa maemo a kelello le maemo a antioxidant a bokong, mme ea fokotsa liso tsa boko le masihla a amyloid (,,,).

Phuputso e le 'ngoe ea libeke tse 12 ho batho ba baholo ba phetseng hantle ba 111 e fumane hore ho nka 150 mg ea GSE letsatsi le letsatsi e ntlafalitse tlhokomelo, puo, le mohopolo o potlakileng le o liehang ().

Leha ho le joalo, lithuto tsa batho mabapi le ts'ebeliso ea GSE ho batho ba baholo ba nang le mohopolo o neng o le teng kapa likhaello tsa kutloisiso lia haella.

Kakaretso GSE e bonts'a monyetla oa ho thibela litšobotsi tse ngata tse senyehang tsa boko le ts'oaetso ea kelello. Leha ho le joalo, lithuto tsa batho tse ling lia hlokahala.

6. E ka ntlafatsa ts'ebetso ea liphio

Liphio tsa hau li angoa haholo ke tšenyo ea oxidative, eo hangata e ke keng ea etsolloa.

Liphuputso tsa liphoofolo li bonts'itse hore GSE e ka fokotsa tšenyo ea liphio le ho ntlafatsa ts'ebetso ka ho fokotsa khatello ea mali le ts'enyo ea ts'oaetso (,,).

Phuputsong e 'ngoe, batho ba 23 ba fumanoeng ba e-na le ho hloleha ho sa foleng ha renal ba ile ba fuoa ligrama tsa 2 tsa GSE letsatsi le letsatsi ka likhoeli tse 6 ebe ba bapisoa le sehlopha sa placebo. Protheine ea Urinary e fokotsehile ka 3% mme ho hloekisa liphio ho ntlafalitsoe ka 9%.

Sena se bolela hore liphio tsa ba sehlopheng sa liteko li ne li khona ho sefa moroto ho feta liphio tsa ba sehlopheng sa placebo ().

Kakaretso GSE e ka fana ka tšireletso khahlanong le tšenyo ea khatello ea mali le ho ruruha, ka hona ea phahamisa bophelo bo botle ba liphio.

7. E ka thibela kholo e tšoaetsanoang

GSE e bonts'a litšepiso tse ts'episang tsa antibacterial le antifungal.

Boithuto bo bonts'itse hore GSE e thibela kholo ea libaktheria tse tloaelehileng tsa lijo, ho kenyeletsoa Campylobacter le E. coli, tseo ka bobeli li atisang ho ikarabella bakeng sa chefo e matla ea lijo le ho ferekana mpeng (33, 34).

Lithutong tsa laboraka, GSE e fumanoe e thibela mefuta e 43 ea lithibela-mafu tse loantšang lithibela-mafu Staphylococcus aureus libaktheria ().

Candida ke fungus e tloaelehileng e kang tomoso eo ka linako tse ling e ka hlahisang candida e fetang, kapa thrush. GSE e sebelisoa haholo kalafong ea setso e le pheko ea candida.

Phuputsong e le 'ngoe, litoeba tse nang le candidiasis ea botšehaling li ile tsa fuoa tharollo ea GSE ea ka mpeng matsatsing a mang le a mang a 2 ka matsatsi a 8. Ts'oaetso e ile ea thibeloa kamora matsatsi a 5 mme ea latela ea 8 ().

Ka bomalimabe, lithuto tsa batho ka bokhoni ba GSE ba ho thusa ho phekola tšoaetso li ntse li haella.

Kakaretso GSE e ka thibela likokoana-hloko tse fapaneng mme ea fana ka ts'ireletso khahlano le likokoana-hloko tse hanyetsanang le lithibela-mafu, mafu a bakiloeng ke baktheria le mafu a fungal joalo ka candida.

8. E ka fokotsa kotsi ea mofets'e

Lisosa tsa mofetše li rarahane, leha tšenyo ea DNA e le tšobotsi e bohareng.

Ho noa haholo li-antioxidants, joalo ka flavonoids le proanthocyanidins, ho amahanngoa le kotsi e fokotsehileng ea mofetše o fapaneng ().

Ts'ebetso ea antioxidant ea GSE e bonts'itse monyetla oa ho thibela matsoele a motho, matšoafo, gastric, lisele tsa molomo tsa squamous, sebete, prostate le methapo ea lisele tsa pancreatic maemong a lab (,,,).

Lithutong tsa liphoofolo, GSE e bonts'itsoe ho ntlafatsa phello ea mefuta e fapaneng ea chemotherapy (,,).

GSE e bonahala e sireletsa khahlanong le khatello ea mali le chefo ea sebete ha e ntse e shebile mohato oa chemotherapy liseleng tse nang le mofetše (,,).

Tlhahlobo ea lithuto tsa liphoofolo tse 41 e fumane hore GSE kapa proanthocyanidins li fokolitse chefo e bakoang ke mofets'e le tšenyo ho tsohle ntle le e 'ngoe ea lithuto ().

Hopola hore lithibela-mafu tsa GSE le proanthocyanidins e kanna ea se fetisoe ka kotloloho ho batho ba nang le mofetše. Ho hlokahala lithuto tse ling ho batho.

Kakaretso Lithutong tsa laboraka, GSE e bontšitsoe e thibela mofetše ka mefuta e fapaneng ea lisele tsa motho. GSE e boetse e bonahala e fokotsa chefo e bakoang ke chemotherapy lithutong tsa liphoofolo ntle le ho ama kalafo hampe. Liphuputso tse ling tse entsoeng ke batho lia hlokahala.

9. E ka sireletsa sebete sa hau

Sebete sa hau se bapala karolo ea bohlokoa ho feliseng lintho tse kotsi tse hlahisitsoeng ke 'mele oa hau ka lithethefatsi, tšoaetso ea vaerase, lintho tse silafatsang, joala le tse ling.

GSE e bonahala e na le tšireletso sebeteng sa hau.

Lithutong tsa li-test-tube, GSE e fokolitse ho ruruha, e sebelisitse li-antioxidants hape e sirelelitsoe khahlanong le tšenyo e mpe ea mahala nakong ea ts'oaetso ea chefo (,,).

Enzyme ea sebete alanine aminotransferase (ALT) ke sesupo sa bohlokoa sa chefo ea sebete, ho bolelang hore maemo a eona a phahama ha sebete se senyehile ().

Phuputsong e 'ngoe, batho ba 15 ba nang le lefu la sebete le se nang joala le maemo a phahameng a ALT ba ile ba fuoa GSE likhoeli tse 3. Li-enzyme tsa sebete li ne li beiloe leihlo khoeli le khoeli, 'me liphetho li bapisoa le ho nka ligrama tse 2 tsa vithamine ea C ka letsatsi.

Kamora likhoeli tsa 3, sehlopha sa GSE se ile sa fumana phokotso ea 46% ho ALT, ha sehlopha sa vithamine C se bonts'a phetoho e nyane ().

Kakaretso GSE e bonahala e sireletsa sebete sa hau khahlanong le chefo le tšenyo e bakoang ke lithethefatsi. Leha ho le joalo, lithuto tsa batho tse ling lia hlokahala.

10. E ntlafatsa pholiso ea leqeba le chebahalo

Liphuputso tse 'maloa tsa liphoofolo li fumane hore GSE e ka thusa ho folisa maqeba (,, 52).

Lithuto tsa batho le tsona li bontša tšepiso.

Phuputsong e 'ngoe e joalo, batho ba baholo ba 35 ba phetseng hantle ba ileng ba etsoa opereishene e nyane ba fuoe tranelate ea 2% ea GSE kapa placebo. Ba sebelisang tranelate ea GSE ba ile ba fola ka ho felletseng ka maqeba kamora matsatsi a 8, ha sehlopha sa placebo se nkile matsatsi a 14 ho fola.

Liphetho tsena li kanna tsa ba teng ka lebaka la li-proanthocyanidins tse phahameng ho GSE tse bakang ho hlahisoa ha lintlha tsa kholo letlalong ().

Phuputsong e 'ngoe ea libeke tse 8 ho bahlankana ba 110 ba phetseng hantle, tranelate ea 2% ea GSE e ntlafalitse ponahalo ea letlalo, ho tiea le sebum, e ka thusang ho fokotsa matšoao a botsofali ().

Kakaretso Litlolo tsa GSE li bonahala li eketsa mabaka a kholo letlalong la hao. Kahoo, li ka thusa ho folisa maqeba le ho thusa ho fokotsa matšoao a botsofali ba letlalo.

Litla-morao tse ka bang teng

Ka kakaretso GSE e nkoa e sireletsehile ka litla-morao tse fokolang.

Litekanyo tsa likarolo tse ka bang 300-800 mg ka letsatsi bakeng sa libeke tse 8-16 li fumanoe li bolokehile ebile li mamellehile bathong ().

Baimana kapa ba anyesang ba lokela ho e qoba, kaha ho na le tlhaiso-leseling e sa lekanang ka litlamorao tsa eona ho baahi bana.

GSE e ka fokotsa khatello ea mali, ea fokotsa mali a hao, mme ea eketsa phallo ea mali, ka hona tlhokomeliso e eletsoa bakeng sa ba noang meriana e fokotsang mali kapa khatello ea mali (,,).

Ntle le moo, e ka fokotsa ho monya ha tšepe, hape ea ntlafatsa ts'ebetso ea sebete le metabolism ea lithethefatsi. Ikopanye le mofani oa tlhokomelo ea bophelo pele u nka li-supplements tsa GSE (,).

Kakaretso GSE e bonahala e mamelloa hantle. Leha ho le joalo, basali ba baimana le ba anyesang ba lokela ho e qoba. Hape, ba noang meriana e itseng ba lokela ho bua ka ho nka tlatsetso ena le mofani oa bona oa tlhokomelo ea bophelo.

Ntlha ea bohlokoa

Ho ntšoa peo ea morara (GSE) ke tlatsetso ea lijo e entsoeng ka peo ea morara.

Ke mohloli o matla oa li-antioxidants, haholo-holo proanthocyanidins.

Li-antioxidants ho GSE li ka thusa ho fokotsa khatello ea mali, ho ruruha le tšenyo ea lisele tse ka hlahang hammoho le mafu a sa foleng.

Ka ho tlatselletsa le GSE, u tla fumana melemo ea bophelo bo botle ba pelo, boko, liphio, sebete le letlalo.

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