Ho phekola ho khaotsa ho ilela khoeli ka ho imeloa kelellong

Litaba

• Mefuta e fapaneng ea li-anti-depressing ke life?
• Melemo ea ho imeloa kelellong ke efe nakong ea ho khaotsa ho ilela khoeli?
• Ke litla-morao life tsa ho imeloa kelellong?
• Na li-anti-depressing li sireletsehile?
• Lefu la Serotonin
• Ntlha ea bohlokoa

Ho imeloa kelellong ke eng?

Ho imeloa kelellong ke meriana e thusang ho phekola matšoao a khatello ea maikutlo. Kameho e kholo ea mofuta oa k'hemik'hale e bitsoang neurotransmitter. Li-neurotransmitters li tsamaisa melaetsa lipakeng tsa lisele tse bokong ba hau.

Leha e na le mabitso, li-anti-depressing li ka phekola maemo a fapaneng ntle le khatello ea maikutlo. Tsena li kenyelletsa:

• ho tšoenyeha le ho tšoha
• mathata a ho ja
• ho hlobaela
• bohloko bo sa foleng
• migraine

Ho imeloa kelellong ho ka thusa ho sebetsana le matšoao a ho khaotsa ho ilela khoeli. Bala pele ho ithuta haholoanyane ka melemo ea ho imeloa kelellong nakong ea ho ilela khoeli.

Mefuta e fapaneng ea li-anti-depressing ke life?

Ho na le mefuta e mene e meholo ea ho imeloa kelellong:

• Selectional serotonin reuptake inhibitors (SSRIs). SSRIs e eketsa palo ea serotonin ea methapo ea kutlo bokong ba hau. Hangata lingaka li fana ka tsona pele hobane li baka litla-morao tse fokolang haholo.
• Serotonin-norepinephrine reuptake inhibitors (SNRIs). SNRI e eketsa palo ea serotonin le norepinephrine bokong ba hau.
• Tricyclic ho imeloa kelellong. Tsena li boloka serotonin le norepinephrine e ngata li fumaneha bokong ba hao.
• Monoamine oxidase inhibitors (MAOIs). Serotonin, norepinephrine, le dopamine kaofela ke monoamine. Monoamine ke mofuta oa methapo ea kutlo. 'Mele oa hau ka tlhaho o etsa enzyme e bitsoang monoamine oxidase e ba senyang. MAOIs a sebetsa ka ho thibela enzyme ena hore e se ke ea sebetsa ho li-monoamine bokong ba hau. Leha ho le joalo, MAOIs ha e sa fanoa hangata, kaha e ka baka litla-morao tse tebileng.

Melemo ea ho imeloa kelellong ke efe nakong ea ho khaotsa ho ilela khoeli?

Ho imeloa kelellong ho ka u imolla matšoao a vasomotor a ho khaotsa ho ilela khoeli. Matšoao a Vasomotor a kenyelletsa methapo ea mali. Li kenyelletsa lintho tse kang:

• mahlasedi a chesang
• mofufutso bosiu
• ho phunya letlalo

Tsena ke tse ling tsa matšoao a tloaelehileng a ho khaotsa ho ilela khoeli. Boholo ba basali ba khaotsang ho ilela khoeli ba ba le matšoao ana, ho hlokometse phuputso ea 2014.

Liphuputso li bontša hore tekanyetso e tlase ea SSRIs kapa SNRI e ka thusa ho fokotsa matšoao a vasomotor, haholoholo mahlaseli a chesang le mofufutso bosiu. Mohlala, ho fumanoe hore lethal dose e tlase ea SNRI venlafaxine (Effexor) e sebelitse hoo e batlang e le kalafo ea lihormone ea setso bakeng sa ho fokotsa mahlaseli a chesang.

E 'ngoe ho tloha ka 2015 e fumane hore tekanyetso e tlase ea SSRI paroxetine (Paxil) e ntlafalitse boleng ba boroko ho basali ba fetang nakong ea ho khaotsa ho ilela khoeli. Boroko bo ntlafetseng ba barupeluoa bo bakiloe ke matšoao a fokolang a vasomotor bosiu ha ba ntse ba nka paroxetine.

Liphetho tsa liteko tsena lia ts'episa, empa litsebi li ntse li sa tsebe hantle hore na hobaneng li-SSRI le SNRIs li fokotsa matšoao a vasomotor. E kanna ea amana le bokhoni ba bona ba ho lekanya maemo a norepinephrine le serotonin. Li-neurotransmitters tsena ka bobeli li thusa ho tsitsisa mocheso oa 'mele.

Hopola hore li-anti-depressing li tsejoa feela ho thusa ka mahlaseli a chesang le ho fufuleloa bosiu. Haeba u batla ho phekola matšoao a mang a ho khaotsa ho ilela khoeli, phekolo ea lihormone e ka ba khetho e atlehang haholoanyane.

Ke litla-morao life tsa ho imeloa kelellong?

Ho imeloa kelellong ho ka baka litla-morao tse fapaneng. Hangata li-SSRI li baka litla-morao tse fokolang haholo. Ngaka ea hau e kanna ea fana ka maikutlo a ho leka mofuta ona pele.

Litla-morao tse tloaelehileng mefuteng e fapaneng ea ho imeloa kelellong li kenyelletsa:

• molomo o omileng
• ho nyekeloa ke pelo
• ho tshoha
• ho hloka botsitso
• ho hlobaela
• mathata a thobalano, joalo ka ho se sebetse ha erectile

Tricyclic antidepressants, ho kenyeletsoa amitriptyline, e ka baka litla-morao tse ling, joalo ka:

• pono e lerootho
• pipitlelano
• marotholi a khatello ea mali ha a eme
• poloko ya moroto
• Ho otsela

Litla-morao tsa ho imeloa kelellong le tsona lia fapana lipakeng tsa meriana, esita le ka har'a mofuta o tšoanang oa ho imeloa kelellong. Sebetsa le ngaka ea hau ho khetha moriana o tepelletsang maikutlo o fanang ka molemo o moholo ka litla-morao tse fokolang. U kanna ua tlameha ho leka tse 'maloa pele u ka fumana e sebetsang.

Na li-anti-depressing li sireletsehile?

Ho imeloa kelellong hangata ho bolokehile. Leha ho le joalo, meriana e mengata ea ho imeloa kelellong e sebelisetsoang matšoao a ho khaotsa ho ilela khoeli e nkoa e le tšebeliso e seng ea mabitso. Sena se bolela hore baetsi ba ho imeloa kelellong ha ba so ka ba etsa liteko tse ts'oanang tse thata ho netefatsa polokeho le katleho ha ho tluoa ho phekoleng mahlaseli a chesang le mofufutso bosiu.

Ho na le moriana o le mong o bitsoang Brisdelle o ithutiloeng ke U.S. Food and Drug Administration (FDA) ka ho khetheha ho phekola matšoao a vasomotor. E bontšitsoe e sebetsa ho fokotsa ho chesa ho chesang le ho fufuleloa bosiu nakong ea ho khaotsa ho ilela khoeli.

Ho imeloa kelellong ho ka boela ha sebelisana le meriana e meng, kahoo etsa bonnete ba hore u bolella ngaka ea hau ka meriana eohle eo u e sebelisang. Sena se kenyelletsa livithamini le litlatsetso hape.

U lokela hape ho joetsa ngaka ea hau haeba u na le:

• cholesterol e phahameng
• nalane ea lefu la pelo
• kotsi e eketsehileng ea tlhaselo ea pelo kapa stroke
• glaucoma
• prostate e atolositsoeng

Ngaka ea hau e ka u thusa ho lekanya melemo le likotsi tsa ho sebelisa li-anti-depressing bakeng sa matšoao a ho ilela khoeli.

Lefu la Serotonin

Serotonin syndrome ke boemo bo sa tloaelehang empa bo tebile bo etsahalang ha maemo a hau a serotonin a phahame haholo. Hangata ho etsahala ha o sebelisa li-anti-depressing, haholo-holo MAOI, ka meriana e meng, litlatsetso, kapa lithethefatsi tse seng molaong tse eketsang maemo a hau a serotonin.

Lintho tse ka sebelisanang le ho imeloa kelellong le ho baka serotonin syndrome li kenyelletsa

• Dextromethorphan. Ena ke sesebelisoa se tloaelehileng merianeng e batang ea ho hatsela le ea sefuba.
• Litlhapi. Tsena ke mofuta oa meriana ea li-antimigraine.
• Litlama tsa litlama. Tsena li kenyelletsa ginseng le St. John's wort.
• Lithethefatsi tse seng molaong. Tsena li kenyelletsa LSD, ecstasy, cocaine le amphetamine.
• Lithethefatsi tse ling tsa ho imeloa kelellong.

Batla phekolo ea meriana ea tšohanyetso haeba u e-na le litla-morao tsena ha u ntse u noa meriana ea ho imeloa kelellong:

• pherekano
• mesifa le ho thothomela
• ho satalla ha mesifa
• ho fufuleloa
• ho otla ha pelo kapele
• maikutlo a fetelletseng
• bana ba hlatsoitsoeng
• sethoathoa
• ho se arabele

Ntlha ea bohlokoa

Ho sebetsana le mahlaseli a chesang le ho fufuleloa bosiu ke e 'ngoe ea litšebeliso tse tsebahalang haholo tsa li-anti-depressing tse ling. Haufinyane, FDA e amohetse ts'ebeliso ea Brisdelle bakeng sa matšoao ana.

Moriana o tlase oa lithibela-mafu hangata o baka litla-morao tse fokolang mme o fokotsa likotsi tse itseng tsa kalafo ea lihormone. Leha ho le joalo, ho imeloa kelellong ho thusa feela ka matšoao a itseng a ho khaotsa ho ilela khoeli. Sebetsa le ngaka ea hau ho fumana kalafo e atlehang ka ho fetisisa bakeng sa matšoao a hau.