Sengoli: Gregory Harris
Letsatsi La Creation: 16 April 2021
Ntlafatsa Letsatsi: 18 November 2024
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Teko ea Hormone ea Anti-Müllerian - Moriana
Teko ea Hormone ea Anti-Müllerian - Moriana

Litaba

Teko ea anti-müllerian hormone (AMH) ke eng?

Teko ena e lekanya boemo ba hormone ea anti-müllerian (AMH) maling. AMH e entsoe ka lisele tsa ho ikatisa tsa banna le basali. Karolo ea AMH le hore na maemo a tloaelehile ho latela lilemo tsa hau le bong.

AMH e bapala karolo ea bohlokoa kholisong ea litho tsa thobalano ho lesea le e-so hlahe. Nakong ea libeke tsa pele tsa bokhachane, lesea le tla qala ho hlahisa litho tsa ho ikatisa. Lesea le se le ntse le e-na le liphatsa tsa lefutso ho fetoha e motona (liphatsa tsa lefutso tsa XY) kapa tse tšehali (liphatsa tsa lefutso tsa XX).

Haeba lesea le na le liphatsa tsa lefutso tsa banna (XY), ho etsoa litekanyetso tse phahameng tsa AMH, hammoho le lihomone tse ling tsa banna. Sena se thibela nts'etsopele ea litho tsa basali mme se khothaletsa sebopeho sa litho tsa botona. Haeba ho se na AMH e lekaneng ho emisa kholo ea litho tsa basali, litho tsa bong ka bobeli li ka theha. Ha sena se etsahala, litho tsa botona kapa tsa botšehali li ka 'na tsa se ke tsa tsejoa ka ho hlaka e le e motona kapa e motšehali. Sena se tsejoa e le genitalia e sa hlakang. Lebitso le leng la boemo bona ke intersex.


Haeba lesea le e-s'o hlahe le e-na le liphatsa tsa lefutso tsa basali (XX), ho etsoa li-AMH tse nyane. Sena se lumella kholo ea litho tsa basali tsa ho ikatisa. AMH e na le karolo e fapaneng bakeng sa basali kamora bocha. Ka nako eo, mae a bomme (litšoelesa tse etsang lisele tsa mahe) a qala ho etsa AMH. Ha lisele tsa mahe li le ngata, boemo ba AMH bo phahame.

Basali, maemo a AMH a ka fana ka leseli mabapi le tsoalo, bokhoni ba ho ima. Teko e kanna ea sebelisoa ho thusa ho fumana mafu a ho ilela khoeli kapa ho lekola bophelo bo botle ba basali ba nang le mefuta e meng ea mofetše oa mae a bomme.

Mabitso a mang: Teko ea lihormone ea AMH, müllerian-inhibiting hormone, MIH, müllerian inhibiting factor, MIF, müllerian-inhibiting drug, MIS

E sebelisetsoa eng?

Hangata ho sebelisoa tlhahlobo ea AMH ho lekola bokhoni ba mosali ba ho hlahisa mahe a ka nontšitsoeng nakong ea bokhachane. Mae a bomme a ka etsa mahe a likete nakong ea lilemo tsa hae tsa pelehi. Palo ea fokotseha ha mosali a ntse a tsofala. Methati ea AMH e thusa ho bonts'a hore na mosali o siile lisele tse kae tsa mahe. Sena se tsejoa e le polokelo ea mae a bomme.


Haeba pokello ea mosali ea mae a bomme e phahame, a ka ba le monyetla o motle oa ho ima. A kanna a khona ho emela likhoeli kapa lilemo pele a leka ho ima. Haeba pokello ea mae a bomme e le tlase, ho ka bolela hore mosali o tla ba le bothata ba ho ima, mme ha a lokela ho lieha nako e telele pele a leka ho ba le ngoana.

Liteko tsa AMH li kanna tsa sebelisoa ho:

  • Bolela qaleho ea ho khaotsa ho ilela khoeli, nako bophelong ba mosali ha nako ea hae ea ho ilela khoeli e khaolitse 'me a ke ke a hlola a ima. Hangata e qala ha mosali a le lilemo tse ka bang 50.
  • Fumana lebaka la ho khaotsa ho ilela khoeli pele
  • Thusa ho fumana lebaka la amenorrhea, khaello ea ho ilela khoeli. Hangata ho fumanoa ho banana ba e-s'o qale ho ea khoeling ka lilemo tse 15 le ho basali ba hlolohetsoeng linako tse 'maloa.
  • Thusa ho fumana polycystic ovary syndrome (PCOS), lefu la lihormone e leng sesosa se tloaelehileng sa ho hloka thari ha basali, ho se khone ho ima
  • Lekola masea a nang le litho tsa botona kapa botšehali tse sa tsejoeng ka ho hlaka e le e motona kapa e motšehali
  • Hlahloba basali ba nang le mefuta e meng ea mofetše oa mae a bomme

Hobaneng ke hloka tlhahlobo ea AMH?

U kanna ua hloka tlhahlobo ea AMH haeba u mosali ea nang le bothata ba ho ima. Teko e ka thusa ho bonts'a menyetla ea ho emola ngoana. Haeba u se u ntse u bona setsebi sa tsoalo, ngaka ea hau e ka sebelisa tlhahlobo ho bona hore na u tla arabela hantle kalafong, joalo ka in vitro fertilization (IVF).


Maemo a phahameng a ka bolela hore o ka ba le mahe a mangata mme o tla arabela hantle kalafong. Maemo a tlase a AMH a bolela hore o ka ba le mahe a fokolang mme o ka se arabele hantle kalafong.

U kanna ua hloka teko ea AMH haeba u mosali ea nang le matšoao a polycystic ovary syndrome (PCOS). Tsena li kenyelletsa:

  • Mathata a ho ilela khoeli, ho kenyelletsa le nako ea pele ea ho ilela khoeli kapa amenorrhea
  • Makhopho
  • Khōlo e feteletseng ea 'mele le sefahleho
  • Ho fokotsa boholo ba matsoele
  • Boima ba 'mele

Ntle le moo, o kanna oa hloka tlhahlobo ea AMH haeba u ntse u alafshoa ke mofetše oa mae a bomme. Teko e ka thusa ho bonts'a haeba kalafo ea hau ea sebetsa.

Ho etsahalang nakong ea tlhahlobo ea AMH?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea AMH.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Haeba u mosali ea lekang ho ima, liphetho tsa hau li ka thusa ho bonts'a menyetla ea ho emola. E ka u thusa le ho etsa qeto ea ho leka ho ima. Boemo bo phahameng ba AMH bo ka bolela hore menyetla ea hau e betere mme o ka ba le nako e ngata pele o leka ho ima.

Boemo bo phahameng ba AMH bo ka boela ba bolela hore o na le polycystic ovary syndrome (PCOS). Ha ho na pheko bakeng sa PCOS, empa matšoao a ka laoloa ka meriana le / kapa liphetoho tsa bophelo, joalo ka ho boloka phepo e nepahetseng le ho oela kapa ho kuta litelu ho tlosa moriri o feteletseng oa 'mele.

Boemo bo tlase bo ka bolela hore o ka ba le bothata ba ho ima. Ho ka boela ha bolela hore u qala ho khaotsa ho ilela khoeli. Boemo bo tlase ba AMH bo tloaelehile ho banana ba banyenyane le ho basali kamora ho ilela khoeli.

Haeba u alafshoa ke mofetše oa mae a bomme, tlhahlobo ea hau e ka bonts'a hore na kalafo ea hau ea sebetsa.

Ho lesea la lesea, boemo bo tlase ba AMH bo ka bolela bothata ba lefutso le / kapa ba lihormone bo bakang litho tsa botona kapa botšehali tse sa hlakileng hore ke tsa banna kapa tsa basali. Haeba maemo a AMH a tloaelehile, ho ka bolela hore lesea le na le li-testicles tse sebetsang, empa ha li sebakeng se nepahetseng. Boemo bona bo ka phekoloa ka ho buuoa le / kapa kalafo ea lihormone.

Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea AMH?

Haeba u mosali ea alafatsoang mathata a tsoalo, mohlomong u tla fumana liteko tse ling hammoho le AMH. Tsena li kenyelletsa liteko tsa estradiol le FSH, lihormone tse peli tse amehang ho hlahiseng.

Litšupiso

  1. Carmina E, Fruzzetti F, Lobo RA. Ho eketseha ha li-hormone tsa anti-Mullerian le boholo ba mae a bomme sehlopheng sa basali ba nang le ts'ebetso ea hypothalamic amenorrhea: ho khetholla ho eketsehileng ha kamano pakeng tsa polycystic ovary syndrome le hypothalamic amenorrhea. Am J Obstet Gynecol [Inthanete]. 2016 Jun [e qotsitsoeng ka 2018 Phato 11]; EA-214 (6): 714.e1–714.e6. E fumaneha ho tsoa ho: https://www.ncbi.nlm.nih.gov/pubmed/26767792
  2. Setsi sa Meriana e Tsoalang Pele [Inthanete]. Houston: Ho HlokahalaTexas.com; c2018. Teko ea AMH; [e qotsitsoeng ka la 2018 Tlhakubele 11]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.infertilitytexas.com/amh-testing
  3. Grynnerup AG, Lindhard A, Sørensen S. Karolo ea anti-Müllerian hormone ho tsoalo ea basali le ho hloka thari-kakaretso. Acta Obstet Scand [Inthanete]. 2012 Nov [e qotsitsoeng ka 2018 Dec 11]; 91 (11): 1252-60. E fumaneha ho tsoa ho: https://www.ncbi.nlm.nih.gov/pubmed/22646322
  4. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Hormone e khahlanong le Müllerian; [e ntlafalitsoeng 2018 Sep 13; e qotsitsoe ka 2018 Phato 11; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/anti-mullerian-hormone
  5. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Ho khaotsa ho ilela khoeli; [e ntlafalitsoeng 2018 ka la 30 Mots'eanong; e qotsitsoeng ka 2018 Phato 11]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/conditions/menopause
  6. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Polycystic Ovary Syndrome; [e ntlafalitsoeng 2018 Oct 18; e qotsitsoe ka 2018 Phato 11; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/conditions/polycystic-ovary-syndrome
  7. Mayo Clinic [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1998–2018. Amenorrhea: Matšoao le lisosa; 2018 Mmesa 26 [e qotsitsoeng ka la 2018 Dec 11]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.mayoclinic.org/diseases-conditions/amenorrhea/symptoms-causes/syc-20369299
  8. Mayo Clinic [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1998–2018. In vitro fertilization (IVF): Mabapi le; 2018 Mar 22 [e qotsitsoeng ka 2018 Phato 11]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.mayoclinic.org/tests-procedures/in-vitro-fertilization/about/pac-20384716
  9. Mayo Clinic [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1998–2018. Lekala le sa hlahlojoang: Tlhahlobo le kalafo; 2017 Aug 22 [e qotsitsoeng ka 2018 Phato 11]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayoclinic.org/diseases-conditions/undescended-testicle/diagnosis-treatment/drc-20352000
  10. Mayo Clinic: Mayo Medical Laboratories [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1995–2018. ID ea Teko: AMH: Hormone ea Antimullerian (AMH), Serum: Kliniki le Tlhaloso; [e qotsitsoeng ka la 2018 Tlhakubele 11]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/89711
  11. Mayo Clinic: Mayo Medical Laboratories [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1995–2018. ID ea Teko: AMH: Hormone ea Antimullerian (AMH), Serum: Kakaretso; [e qotsitsoeng ka la 2018 Tlhakubele 11]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.mayocliniclabs.com/test-catalog/Overview/89711
  12. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali; [e qotsitsoeng ka la 2018 Tlhakubele 11]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
  13. NIH Laeborari ea Naha ea Bongaka ea NIH U.S. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liphatsa tsa lefutso tsa AMH; 2018 Phato 11 [e qotsitsoeng ka la 2018 Phato 11]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://ghr.nlm.nih.gov/gene/AMH
  14. NIH Laeborari ea Naha ea Bongaka ea NIH U.S. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Müllerian aplasia le hyperandrogenism; 2018 Phato 11 [e qotsitsoeng ka 2018 Pherekhong 11]; [li-skrini tse ka bang 2].E fumaneha ho tsoa ho: https://ghr.nlm.nih.gov/condition/mullerian-aplasia-and-hyperandrogenism
  15. Metsoalle ea Meriana ea Tsoalo ea New Jersey [Marang-rang]. RMANJ; c2018. Teko ea Hormone ea Anti-Mullerian Hormone (AMH) ea Ovarian Reserve; 2018 Sep 14 [e qotsitsoeng ka 2018 Dec 11]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.rmanj.com/anti-mullerian-hormone-amh-testing-of-ovarian-reserve
  16. Sagsak E, Onder A, Ocal FD, Tasci Y, Agladioglu SY, Cetinkaya S Aycan Z. Primary Amenorrhea Secondary ho ea Mullerian Anomaly. J Case Rep [Marang-rang]. 2014 Mar 31 [e qotsitsoeng ka la 2018 Dec 11]; Khatiso e Khethehileng: doi: 10.4172 / 2165-7920.S1-007. E fumaneha ho tsoa ho: https://www.omicsonline.org/open-access/primary-amenorrhea-secondary-to-mullerian-anomaly-2165-7920.S1-007.php?aid=25121

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.

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