Sengoli: Joan Hall
Letsatsi La Creation: 4 Hlakubele 2021
Ntlafatsa Letsatsi: 23 November 2024
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How Does Furosemide Work? Understanding Loop Diuretics
Video: How Does Furosemide Work? Understanding Loop Diuretics

Litaba

Furosemide ke diuretic e matla ('pilisi ea metsi') mme e ka baka ho felloa ke metsi 'meleng le ho se leka-lekane ha electrolyte. Ho bohlokoa hore o e nke hantle feela joalokaha ho laetsoe ke ngaka ea hau. Haeba u e-na le matšoao a latelang, letsetsa ngaka hang-hang: ho fokotsa ho ntša metsi; molomo o omileng; lenyora; ho nyekeloa ke pelo; ho hlatsa; bofokoli; ho otsela; pherekano; bohloko ba mesifa kapa cramps; kapa ho otla ha pelo ka potlako kapa ka potlako.

Furosemide e sebelisoa e le mong kapa e kopane le meriana e meng ho alafa khatello e phahameng ea mali. Furosemide e sebelisetsoa ho phekola edema (ho boloka metsi, mokelikeli o feteletseng o tšoaretsoeng lisele tsa 'mele) o bakoang ke mathata a fapaneng a bongaka, ho kenyelletsa lefu la pelo, liphio le lefu la sebete. Furosemide o sehlopheng sa meriana e bitsoang diuretics ('lipilisi tsa metsi'). E sebetsa ka ho etsa hore liphio li tlose metsi a sa hlokahaleng le letsoai le tsoang 'meleng ho ea morong.

Khatello ea mali e phahameng ke boemo bo tloaelehileng 'me ha e sa phekoloe, e ka baka tšenyo bokong, pelong, methapong ea mali, liphio le likarolong tse ling tsa' mele. Tšenyo ea litho tsena e ka baka lefu la pelo, lefu la pelo, ho hloleha ha pelo, stroke, ho hloleha ha liphio, ho se bone hantle le mathata a mang. Ntle le ho noa moriana, ho etsa liphetoho bophelong ho tla thusa ho laola khatello ea mali. Liphetoho tsena li kenyelletsa ho ja lijo tse se nang mafura le letsoai, ho boloka boima ba 'mele bo phetseng hantle, ho ikoetlisa bonyane metsotso e 30 ka matsatsi a mangata, ho se tsube le ho sebelisa joala ka tekano.


Furosemide e tla joalo ka letlapa ebile e le tharollo (mokelikeli) ho e nka ka molomo. Hangata e nooa hanngoe kapa habeli ka letsatsi. Ha e sebelisoa ho phekola edema, furosemide e ka nkuoa letsatsi le letsatsi kapa feela ka matsatsi a itseng a beke. Ha o sebelisetsoa ho phekola khatello ea meriana ea mali, nka li-furosemide ka nako e le 'ngoe letsatsi ka leng. Latela litaelo tsa lengolo la hau la ngaka ka hloko, 'me u kope ngaka kapa setsebi sa metsoako ho u hlalosetsa karolo efe kapa efe eo u sa e utloisiseng. Nka furosemide hantle feela joalokaha e laetsoe. Se ke oa e noa hanyane kapa ua e noa khafetsa ho feta kamoo u laetsoeng ke ngaka ea hau.

Furosemide e laola khatello e phahameng ea mali le edema empa ha e phekole maemo ana. Tsoela pele ho nka furosemide leha o ikutloa o phetse hantle. Se ke oa emisa ho nka furosemide ntle le ho bua le ngaka ea hau.

Moriana ona ka linako tse ling o laeloa ts'ebeliso e ngoe; botsa ngaka kapa setsebi sa metsoako bakeng sa tlhaiso-leseling e batsi.

Pele o nka furosemide,

  • bolella ngaka le setsebi sa metsoako haeba u na le alejiki ho furosemide, meriana ea sulfonamide, meriana efe kapa efe, kapa metsoako efe kapa efe ea matlapa kapa tharollo ea furosemide. Botsa setsebi sa hau sa meriana kapa u hlahlobe tlhaiso-leseling ea mokuli lethathamong la metsoako.
  • bolella ngaka ea hau le setsebi sa meriana hore na ke meriana e feng eo u e fuoang kapa eo u rerileng ho e nka. Etsa bonnete ba hore o bua ka tse latelang: lithibela-mafu tsa aminoglycoside tse kang amikacin, gentamicin (Garamycin), kapa tobramycin (Bethkis, Tobi); angiotensin-converting enzyme (ACE) inhibitors joalo ka benazepril (Lotensin, Lotrel), captopril (Capoten), fosinopril, lisinopril (Prinzide, ka Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon, Aceon) , ka Accuretic), ramipril (Altace), le trandolapril (Mavik, e Tarka); angiotensin II receptor antagonists (ARB) joalo ka azilsartan (Edarbi, Edarbyclor), candesartan (Atacand, ho Atacand HCT), eprosartan (Teveten, Teveten HCT), irbesartan (Avapro, Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar, ka Azor, Benicar HCT), telmisartan (Micardis, Micardis HCT), le valsartan (Diovan, ho Diovan HCT, Exforge); aspirin le li-salicylate tse ling; li-barbiturate tse kang phenobarbital le secobarbital (Seconal); corticosteroids joalo ka betamethasone (Celestone), budesonide (Entocort), cortisone (Cortone), dexamethasone (Decadron, Dexpak, Dexasone, tse ling), fludrocortisone (Floriner), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol, Meprolone prednisolone (Prelone, tse ling), prednisone (Deltasone, Meticorten, Sterapred, tse ling), le triamcinolone (Aristocort, Azmacort); cisplatin (Platinol); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin), asiti ea ethacrynic (Edecrin); indomethacin (Indocin); litlolo tse tlisang moriana; lithium (Lithobid); meriana ea lefu la tsoekere, khatello e phahameng ea mali le bohloko; methotrexate (Trexall); li-probenecid (Probalan, Probenemid); le phenytoin (Dilantin, Phenytek). Ngaka ea hau e kanna ea hloka ho fetola litekanyetso tsa meriana ea hau kapa ho u beha leihlo ka hloko bakeng sa litla-morao.
  • haeba u nka sucralfate (Carafate), e nke lihora tse 2 pele kapa kamora ho nka furosemide.
  • bolella ngaka ea hau haeba u na le lefu la liphio. Ngaka ea hau e ka u joetsa hore u se ke ua nka furosemide.
  • bolella ngaka ea hau haeba u kile ua ba le boemo bofe bo ka sitisang senya ho tsoa ka botlalo, lefu la tsoekere, gout, systemic lupus erythematosus (SLE, boemo bo sa foleng ba ho ruruha), kapa lefu la sebete.
  • bolella ngaka ea hau haeba u imme, rera ho ima, kapa u anyesa. Se ke oa anyesa letsoele ha u ntse u noa moriana ona. Haeba u ka ima ha u ntse u nka furosemide, letsetsa ngaka.
  • haeba u ntse u etsoa opereishene, bolella ngaka hore u sebelisa furosemide.
  • rera ho qoba ho pepesehela khanya ea letsatsi ho sa hlokahale kapa nako e telele le ho apara liaparo tse sireletsang, likhalase tsa mahlo le setlolo se sireletsang letsatsi. Furosemide e ka etsa hore letlalo la hau le utloe khanya ea letsatsi.
  • U lokela ho tseba hore furosemide e ka baka molikoalikoane, hlooho e bobebe, le ho akheha ha u tsoha kapele haholo u le sebakeng sa leshano. Sena se atile haholo ha o qala ho nka furosemide. Ho qoba bothata bona, tsoha betheng butle, o phomotse maoto fatshe metsotso e mmalwa pele o ema. Joala bo ka eketsa litla-morao tsena.

Haeba ngaka eu fa lijo tse letsoai le tlase kapa tse nang le sodium e tlase, kapa ho ja kapa ho noa lijo tse nang le potasiamo tse ngata (mohlala, libanana, prune, morara o omisitsoeng le lero la lamunu) lijong tsa hau, latela litaelo tsena ka hloko.


Nka lethal dose ha u sa hopola. Leha ho le joalo, haeba e se e le nako ea tekanyetso ea hau e latelang, tlola lethal dose 'me u tsoelepele kemiso ea hau ea kamehla ea likhahla Se ke oa nka lethal dose tse peli ho etsetsa e hlolohetsoeng.

Bolella ngaka ea hau haeba a mang a matšoao ana a le matla kapa a sa fele:

  • ho ntša metsi khafetsa
  • pono e lerootho
  • hlooho e opang
  • pipitlelano
  • letšollo

Litla-morao tse ling li ka ba mpe. Haeba u na le e 'ngoe ea matšoao ana kapa a thathamisitsoeng karolong ea BOHLOKOA BA LITEMOSO, letsetsa ngaka hang-hang kapa u batle phekolo ea tšohanyetso:

  • feberu
  • ho lla ditsebeng
  • ho hloka kutlo
  • lekhopho
  • hives
  • marusu kapa letlalo le ebolang
  • ho hlohlona
  • bothata ba ho hema kapa ho koenya
  • bosehla ba letlalo kapa mahlo

Haeba o ba le litlamorao tse mpe, uena kapa ngaka ea hau le ka romella tlaleho ho Lenaneo la MedWatch Advers Event Reporting inthaneteng (http://www.fda.gov/Safety/MedWatch) inthaneteng kapa ka mohala ( 1-800-332-1088).


Boloka moriana ona ka setshelong seo o keneng ho sona, o koetsoe ka thata, 'me bana ba ke ke ba o fihlela. E boloke ka mocheso oa kamore le hole le mocheso o feteletseng le mongobo (eseng ka kamoreng ea ho hlapela). Lahla tharollo ea furosemide e sa sebelisoang kamora matsatsi a 90.

Ho bohlokoa ho boloka litlhare tsohle li sa bonahale le moo bana ba ka fihlelloang lijana tse ngata (joalo ka likelello tsa lipilisi tsa beke le beke le tsa marotholi a mahlo, litlolo, lipache le li-inhalers) ha li thibele bana mme bana ba banyane ba ka li bula habonolo. Ho sireletsa bana ba banyenyane chefo, lula u notlela likepisi tsa polokeho 'me hang-hang beha meriana sebakeng se sireletsehileng - se holimo le hole le moo ba sa se boneng le ho se fihlela. http://www.upandaway.org

Meriana e sa hlokeheng e lokela ho lahloa ka litsela tse ikhethang ho netefatsa hore liphoofolo tse ruuoang lapeng, bana le batho ba bang ba ke ke ba li sebelisa. Leha ho le joalo, ha ua lokela ho tšela meriana ena ka ntloaneng. Sebakeng seo, tsela e molemohali ea ho lahla meriana ea hau ke ka lenaneo la ho khutlisa moriana. Bua le rakhemisi oa hau kapa ikopanye le lefapha la hau la litšila / la ho li sebelisa hape ho ithuta ka mananeo a khutlisetsang sechaba sa heno. Sheba webosaete ea FDA's Disposal of Medicines websaeteng (http://goo.gl/c4Rm4p) bakeng sa tlhaiso-leseling e batsi haeba u sena mokhoa oa ho khutlisa.

Haeba ho na le overdose, letsetsa mohala oa thuso oa taolo ea chefo ho 1-800-222-1222. Tlhahisoleseling e fumaneha inthaneteng ho https://www.poisonhelp.org/help. Haeba motho ea hlokofalitsoeng a oele, a tšoeroe ke sethoathoa, a na le bothata ba ho hema, kapa a sa khone ho tsosoa, hang-hang letsetsa litšebeletso tsa tšohanyetso ho 911.

Matšoao a ho feta tekano a ka kenyelletsa:

  • lenyora le feteletseng
  • molomo o omileng
  • ho tsekela
  • pherekano
  • mokhathala o feteletseng
  • ho hlatsa
  • mahlaba a ka mpeng

Boloka linako tsohle le ngaka le laboratori. Khatello ea mali ea hau e lokela ho hlahlojoa khafetsa, 'me liteko tsa mali li lokela ho etsoa nako le nako.

Pele o etsa tlhahlobo ea laboratori, bolella ngaka le basebetsi ba laboratori hore o nka furosemide.

Se ke oa lumella mang kapa mang ho noa moriana oa hau. Botsa rakhemisi oa hau lipotso tseo u nang le tsona mabapi le ho tlatsa lengolo la ngaka.

Ho bohlokoa ho uena hore u boloke lethathamo le ngotsoeng la meriana eo u e nkang u sa e ngolla le eo u sa e ngolisetsang (morekisi) le lihlahisoa tse ling tse kang livithamini, liminerale, kapa litlatsetso tse ling tsa phepo. U lokela ho tla le lenane lena nako le nako ha u etela ngaka kapa ha u amoheloa sepetlele. Hape ke tlhaiso-leseling ea bohlokoa ho tsamaea le uena haeba ho ka hlaha maemo a tšohanyetso.

  • Lasix®
E ntlafalitsoe la ho qetela - 09/15/2017

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