Kankere ea Parathyroid

Kankere ea parathyroid ke kankere (e kotsi) kholo ea tšoelesa ea parathyroid.

Litšoelesa tsa parathyroid li laola boemo ba khalsiamo 'meleng. Ho na le litšoelesa tse 4 tsa parathyroid, tse 2 kaholimo ho karolo e 'ngoe le e' ngoe ea qoqotho e fumanehang molaleng.

Kankere ea parathyroid ke mofuta o sa tloaelehang oa mofets'e. E ama banna le basali ka ho lekana. Kankere hangata e hlaha ho batho ba baholo ho feta 30.

Lebaka la mofetše oa parathyroid ha le tsejoe. Batho ba nang le liphatsa tsa lefutso tse bitsoang multiple endocrine neoplasia mofuta oa I le hyperparathyroidism-jaw tumor syndrome ba na le kotsi e kholo ea lefu lena. Batho ba nang le radiation ea hlooho kapa ea molala le bona ba ka ba kotsing e kholo. Empa mofuta ona oa radiation o na le monyetla oa ho baka mofetše oa qoqotho.

Matšoao a mofets'e oa "parathyroid" a bakoa haholo ke khalsiamo e phahameng maling (hypercalcemia) mme a ka ama likarolo tse fapaneng tsa 'mele.

Matšoao a kenyelletsa:

• Bohloko ba masapo
• Ho sokela
• Mokhathala
• Ho robeha hoa dikarolo
• Lenyora khafetsa
• Ho rota khafetsa
• Majoe a liphio
• Bofokoli ba mesifa
• Ho nyekeloa le ho hlatsa
• Takatso e fosahetseng ea lijo

Kankere ea parathyroid e thata haholo ho e fumana.

Ngaka ea hau e tla etsa tlhahlobo ea 'mele ebe e botsa ka nalane ea hau ea bongaka.

Hoo e ka bang halofo ea nako, mofani o fumana mofetše oa parathyroid ka ho utloa molala ka matsoho (palpation).

Sefuba sa mofetše se nang le mofetše se atisa ho hlahisa bongata bo phahameng haholo ba "hormone" ea "parathyroid" (PTH). Liteko tsa hormone ena li ka kenyelletsa:

• K'halsiamo ea mali
• Mali PTH

Pele o etsoa opereishene, o tla ba le scan e khethehileng ea radioactive ea litšoelesa tsa parathyroid. Sesepa se bitsoa scan ea sestamibi. U kanna ua ba le molala oa ultrasound. Liteko tsena li etsoa ho netefatsa hore na ke lefu lefe la parathyroid le sa tloaelehang.

Litlhare tse latelang li ka sebelisoa ho lokisa hypercalcemia ka lebaka la mofetše oa parathyroid:

• Maro a tsoang mothapong (maro a IV)
• Hormone ea tlhaho e bitsoang calcitonin e thusang ho laola boemo ba calcium
• Lithethefatsi tse emisang ho senyeha le ho sebelisoa hoa masapo 'meleng

Phekolo ke kalafo e khothalletsoang bakeng sa mofetše oa parathyroid. Ka linako tse ling, ho thata ho fumana hore na hlahala ea parathyroid e na le mofetše. Ngaka ea hau e ka 'na ea u khothaletsa hore u buuoe u sa hlahlojoa hore na u tšoeroe ke eng. Ho buuoa hanyane ka hanyane ho sebelisoang, ho sebelisoa likhahla tse nyane, ho se ho atile haholo bakeng sa lefu la parathyroid.

Haeba liteko pele ho opereishene li ka fumana tšoelesa e amehileng, ho ka etsoa opereishene ka lehlakoreng le leng la molala. Haeba ho sa khonehe ho fumana bothata ba bothata pele ho opereishene, ngaka e buoang e tla sheba mahlakore ka bobeli a molala oa hau.

Chemotherapy le radiation ha li sebetse hantle ho thibela mofetše ho khutla. Mahlaseli a kotsi a ka thusa ho fokotsa ho ata ha mofets'e masapong.

Ho buuoa khafetsa bakeng sa mofetše o khutlileng ho ka thusa:

• Ntlafatsa sekhahla sa pholoho
• Fokotsa litlamorao tse mpe tsa hypercalcemia

Kankere ea parathyroid e hola butle. Ho buoa ho ka thusa ho lelefatsa bophelo le ha mofetše o ata.

Kankere e ka hasana (metastasize) libakeng tse ling 'meleng, hangata matšoafo le masapo.

Hypercalcemia ke bothata bo tebileng ka ho fetisisa. Boholo ba mafu a bakoang ke mofetše oa parathyroid a hlaha ka lebaka la khatello e matla ea mali, e thata ho e laola, eseng mofets'e ka bo ona.

Kankere hangata e khutla (e ipheta). Ho ka hlokahala lingaka tse ling tsa ho buoa. Mathata a tsoang ho buuoa a ka kenyelletsa:

• Ho kuruma kapa ho fetoha ha lentsoe ka lebaka la tšenyo ea methapo e laolang methapo ea lentsoe
• Tšoaetso sebakeng sa ho buuoa
• Boemo bo tlase ba calcium maling (hypocalcemia), e leng boemo bo ka 'nang ba beha bophelo kotsing
• E qhekellang

Bitsa mofani oa hao oa tlhokomelo ea bophelo haeba u ikutloa u le molaleng molaleng kapa u e-na le matšoao a hypercalcemia.

Parathyroid carcinoma

• Litšoelesa tsa Parathyroid

Asban A, Patel AJ, Reddy S, Wang T, Balentine CJ, Chen H. Kankere ea sistimi ea endocrine. Ka: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, bahlophisi. Abeloff's Clinical Oncology. La 6th. Philadelphia, PA: Elsevier; 2020: khaolo ea 68.

CDlet ea Fletcher. Hlahala ea thyroid le parathyroid litsoelesa. Ka: Fletcher CDM, e hlophisitsoeng. Diagnostic Histopathology ea Lihlahala. La 5th. Philadelphia, PA: Elsevier; 2021: khaolo ea 18.

Webosaete ea National Cancer Institute. Kalafo ea mofets'e ea Parathyroid (PDQ) - mofuta oa litsebi tsa bophelo bo botle. www.cancer.gov/types/parathyroid/hp/parathyroid-tlhare-pdq. E ntlafalitsoe ka la 17 Hlakubele 2017. E fihlile ka la 11 Hlakola 2020.

Torresan F le J Iacobone M. Likarolo tsa bongaka, kalafo le leihlo la hyperparathyroidism-jaw tumor syndrome: Ho fihlela morao-rao le ho lekola lingoliloeng. Int J Endocrinol 2019. E phatlalalitsoe marang-rang Dec 18, 2019. www.hindawi.com/journals/ije/2019/1761030/.