MIBG scintiscan

MIBG scintiscan ke mofuta oa tlhahlobo ea litšoantšo. E sebelisa ntho e ntšang mahlaseli a kotsi (e bitsoang tracer). Sekena se fumana kapa se netefatsa boteng ba pheochromocytoma le neuroblastoma. Tsena ke mefuta ea lihlahala tse amang methapo ea methapo.

Radioisotope (MIBG, iodine-131-meta-iodobenzylguanidine, kapa iodine-123-meta-iodobenzylguanidine) e keneloa ka mothapong. Motsoako ona o khomarela lisele tse itseng tsa hlahala.

O tla ba le scan hamorao letsatsing leo kapa letsatsing le hlahlamang. Bakeng sa karolo ena ea tlhahlobo, u robala tafoleng tlasa letsoho la sekena. Mpa ea hao e hlahlojoa. U kanna ua hloka ho khutla bakeng sa litekanyetso tse pheta-phetoang matsatsi a 1 ho isa ho a mararo. Sesepa ka seng se nka lihora tse 1 ho isa ho tse 2.

Pele kapa nakong ea tlhahlobo, o ka fuoa motsoako oa iodine. Sena se thibela tšoelesa ea qoqotho ea hao hore e se ke ea monya radioisotope e ngata haholo.

O tla hloka ho saena foromo ea tumello e nang le tsebo. O tla kopuoa ho apara moaparo oa sepetlele kapa liaparo tse hlephileng. U tla hloka ho tlosa mabenyane kapa lintho tsa tšepe pele ho scan. Lithethefatsi tse ngata li sitisa tlhahlobo. Botsa mofani oa tlhokomelo ea bophelo hore na ke meriana efe ea hau e tloaelehileng eo u ka e hlokang ho emisa ho e noa pele ho tlhahlobo.

U tla utloa nale e bohale ha lisebelisoa li entoa. Tafole e kanna ea bata kapa ea ba thata. O tlameha ho bua leshano o khutsitse nakong ea scan.

Teko ena e etsoa ho thusa ho fumana pheochromocytoma. E etsoa ha sesebelisoa sa CT se ka mpeng kapa sesebelisoa sa MRI se sa fane ka karabo e hlakileng. E boetse e sebelisoa ho thusa ho fumana lefu la neuroblastoma mme e ka sebelisoa bakeng sa lihlahala tsa carcinoid.

Ha ho na matšoao a hlahala.

Liphetho tse sa tloaelehang li ka supa:

• Pheochromocytoma
• Multiple endocrine neoplasia (MEN) II
• Hlahala Carcinoid
• Neuroblastoma

Ho na le monyetla oa ho pepesehela mahlaseli a kotsi ho radioisotope. Mahlaseli a tsoang seea-le-moea sena a phahame ho feta a mang a mangata. U kanna ua hloka ho nka mehato e meng ea ho itšireletsa matsatsing a 'maloa kamora tlhahlobo. Mofani oa hau o tla u joetsa hore na u nke mehato efe.

Pele kapa nakong ea tlhahlobo, o ka fuoa tharollo ea iodine. Sena se tla etsa hore qoqotho ea hao e se ke ea monya iodine e ngata. Hangata batho ba nka iodide ea potasiamo letsatsi le le leng pele ho matsatsi a 6. Sena se thibela qoqotho ho nka MIBG.

Teko ena HA E ea lokela ho etsoa ho bakhachane. Mahlaseli a kotsi a ka beha lesea le e-song ho hlahe kotsi.

Litšoantšo tsa Adrenal medullary; Meta-iodobenzylguanidine scintiscan; Pheochromocytoma - MIBG; Neuroblastoma - MIBG; Carcinoid MIBG

• Ente ea MIBG

Bleeker G, Tytgat GAM, Adam JA, le al. 123I-MIBG scintigraphy le 18F-FDG-PET ho nka litšoantšo bakeng sa ho fumana lefu la neuroblastoma. Setsi sa Cochrane Database Rev. 2015; (9): CDC009263. PMID: 26417712 phatlalalitsoe.ncbi.nlm.nih.gov/26417712/.

Cohen DL, Fishbein L. Matšoao a phahameng a khatello ea kelello: pheochromocytoma le paraganglioma. Ka: Bakris GL, Sorrentino MJ, bahlophisi. Hypertension: Motsoalle ho Mafu a Pelo a Braunwald. 3rd ed. Philadelphia, PA: Elsevier; 2018: khaolo ea 15.

Lihlahala tsa Oberg K. Neuroendocrine le mathata a amanang le ona. Ho Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, le al. Buka ea Williams ea Endocrinology. La bo14 la ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 45.

Yeh MW, Livhits MJ, Duh QY. Litšoelesa tsa adrenal. Ka: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Buka ea Sabiston ea Ngaka ea ho Buoa. 20th, ed. Philadelphia, PA: Elsevier; 2017: khaolo ea 39.