Teko ea Erythropoietin

Teko ea erythropoietin e lekanya boholo ba hormone e bitsoang erythropoietin (EPO) maling.

Hormone e bolella lisele tsa bakoang mongoaneng oa masapo ho etsa lisele tse khubelu tsa mali. EPO e entsoe ka lisele tse liphio. Lisele tsena li lokolla EPO e eketsehileng ha boemo ba oksijene ea mali bo le tlase.

Ho hlokahala sampole ea mali.

Ha ho litokisetso tse khethehileng tse hlokahalang.

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba utloa feela ho hlaba kapa ho hlaba habohloko. Kamora moo, ho kanna ha ba le ho tsitsipana.

Teko ena e ka sebelisoa ho thusa ho tseba sesosa sa phokolo ea mali, polycythemia (palo e phahameng ea lisele tse khubelu tsa mali) kapa mathata a mang a moko oa masapo.

Phetoho ea lisele tse khubelu tsa mali e tla ama ho lokolloa ha EPO. Mohlala, batho ba nang le phokolo ea mali ba na le lisele tse khubelu tsa mali tse fokolang haholo, kahoo ho hlahisoa EPO e ngata.

Mefuta e tloaelehileng ke li-milliunite tse 2.6 ho isa ho 18.5 ka mililitara (mU / mL).

Mehlala e kaholimo ke litekanyo tse tloaelehileng bakeng sa liphetho tsa liteko tsena. Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li leka liteko tse fapaneng. Bua le mofani oa tlhokomelo ea bophelo mabapi le moelelo oa sephetho sa hau sa tlhahlobo.

Boemo ba EPO bo eketsehileng bo ka bakoa ke polycythemia ea bobeli. Hona ke tlhahiso e fetelletseng ea lisele tse khubelu tsa mali tse etsahalang ho arabela ketsahalo e kang boemo bo tlase ba mali a oksijene. Boemo bo ka hlaha libakeng tse phahameng kapa, ka seoelo, ka lebaka la hlahala e hlahisang EPO.

Boemo ba EPO bo tlase ho feta bo tloaelehileng bo ka bonoa ka ho hloleha ho sa foleng ha liphio, khaello ea mali ea mafu a sa foleng kapa polycythemia vera.

Likotsi tse amanang le ho huloa mali li nyane, empa li ka kenyelletsa:

• Ho tsoa mali a mangata
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Hematoma (mali a bokellanang ka tlasa letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Serum erythropoietin; EPO

Bain BJ. Pheripheral mali smear. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 148.

Kaushansky K. Hematopoiesis le lintlha tsa kholo ea hematopoietic. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 147.

Kremyanskaya M, Najfeld V, Mascarenhas J, Hoffman R. Polycythemias. Ka: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Melao-motheo le Tloaelo ea Motheo. La 7th. Philadelphia, PA: Elsevier Saunders; 2018: khaolo ea 68.

Kumar V, Abbas AK, Aster JC. Sele e khubelu ea mali le mathata a ho tsoa mali. Ka: Kumar P, Clark M, bahlophisi. Bongaka ba Bongaka ba Kumar le Clarke. La 9th. Philadelphia, PA: Elsevier; 2017: khaolo ea 14.