Apolipoprotein B100

Apolipoprotein B100 (apoB100) ke protheine e phethang karolo ea ho tsamaisa k'holeseterole ho potoloha le 'mele oa hau. Ke mofuta oa lipoprotein (LDL) tse tlase.

Liphetoho (liphetoho) ho apoB100 li ka baka boemo bo bitsoang hypercholesterolemia ea lelapa. Ena ke mofuta oa k'holeseterole e phahameng e fetisetsoang malapeng (e futsitsoeng).

Sengoloa sena se bua ka tlhahlobo e sebelisitsoeng ho metha boemo ba apoB100 maling.

Ho hlokahala sampole ea mali.

Mofani oa hao oa tlhokomelo ea bophelo a ka u joetsa hore u se ke ua ja kapa oa noa letho lihora tse 4 ho isa ho tse 6 pele ho tlhahlobo.

Ha nale e kentsoe ho hula mali, o kanna oa utloa bohloko bo mahareng, kapa bohloko feela kapa ho hlaba. Kamora moo, ho kanna ha ba le ho tsitsipana.

Hangata, tlhahlobo ena e etsoa ho thusa ho tseba sesosa kapa mofuta o itseng oa "cholesterol" e phahameng ea mali. Ha ho hlake hore na tlhahisoleseling e thusa ho ntlafatsa kalafo. Ka lebaka la sena, lik'hamphani tse ngata tsa inshorense ea bophelo bo botle HA LI lefe tefo. Haeba O SE na ts'oaetso ea k'holeseterole e phahameng kapa lefu la pelo, tlhahlobo ena e kanna ea se buelloe bakeng sa hau.

Mefuta e tloaelehileng e ka ba 50 ho isa ho 150 mg / dL.

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li laboratori tse ling li sebelisa litekanyo tse fapaneng kapa li ka leka mefuta e fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.

Sephetho se sa tloaelehang se ka bolela hore o na le maemo a phahameng a lipid (mafura) maling a hau. Lentsoe la bongaka bakeng sa sena ke hyperlipidemia.

Mathata a mang a ka amanang le maemo a phahameng a apoB100 a kenyelletsa lefu la methapo ea methapo e kang angina pectoris (bohloko ba sefuba bo hlahang ka ts'ebetso kapa khatello ea maikutlo) le lefu la pelo.

Likotsi tse amanang le ho huloa mali li nyane, empa li ka kenyelletsa:

• Ho tsoa mali a mangata
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Hematoma (mali a hahiloeng ka tlas'a letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)
• Li-punctures tse ngata ho fumana methapo

Litekanyo tsa Apolipoprotein li ka fana ka lintlha tse qaqileng mabapi le kotsi ea lefu la pelo, empa boleng bo ekelitsoeng ba tlhahlobo ena ho feta karolo ea lipid ha bo tsejoe.

ApoB100; Apoprotein B100; Hypercholesterolemia - apolipoprotein B100

• Teko ea mali

Fazio S, Linton MF. Taolo le tumello ea apolipoprotein B e nang le lipoprotein. Ka: Ballantyne CM, e hlophisitsoeng. Clinical Lipidology: Motsoalle ho Mafu a Pelo a Braunwald. Lekhetlo la bobeli. Philadelphia, PA: Elsevier; 2015: khaolo ea 2.

Genest J, Libby P. Lipoprotein mathata le lefu la pelo. Ka: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Lefu la pelo la Braunwald: Buka ea bongaka ea meriana ea pelo. 11th ed. Philadelphia, PA: Elsevier; 2019: khaolo ea 48.

Remaley AT, Mantsiboea TD, Warnick GR. Lipids, lipoprotein, apolipoprotein, le lisosa tse ling tsa kotsi ea pelo. Ka: Rifai N, ed. Tietz ea Buka ea Khemistri ea Kliniki le Diagnostics ea Limolek'hule. La 6th. St Louis, MO: Elsevier; 2018: khaolo ea 34.

Robinson JG. Mathata a metabolism ea lipid. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 195.