Teko ea ALP isoenzyme

Alkaline phosphatase (ALP) ke enzyme e fumanoang liseleng tse ngata tsa 'mele tse kang sebete, methapo ea bile, lesapo le mala. Ho na le mefuta e fapaneng ea ALP e bitsoang isoenzymes. Sebopeho sa enzyme se latela hore na se hlahisoa kae 'meleng. Hangata teko ena e sebelisoa ho leka ALP e entsoeng liseleng tsa sebete le masapo.

Teko ea ALP isoenzyme ke teko ea laborateng e lekanyang boholo ba mefuta e fapaneng ea ALP maling.

Teko ea ALP ke teko e amanang le eona.

Ho hlokahala sampole ea mali. Boholo ba nako mali a huloa mothapong o kahare ho setsoe kapa morao letsohong.

Ha ua lokela ho ja kapa ho noa letho lihora tse 10 ho isa ho tse 12 pele ho tlhahlobo, ntle le haeba mofani oa tlhokomelo ea bophelo a u joetsa joalo.

Meriana e mengata e ka kena-kenana le sephetho sa liteko tsa mali.

• Mofani oa hau o tla u joetsa haeba u hloka ho emisa ho noa meriana efe kapa efe pele u etsa tlhahlobo ena.
• O SE KE WA emisa kapa oa fetola meriana ea hau ntle le ho bua le mofani oa hau pele.

U ka utloa bohloko bo bonyenyane kapa motsu ha nale e kentsoe. U kanna oa utloa ho phatloha hampe setšeng kamora hore mali a huloe.

Ha sephetho sa tlhahlobo ea ALP se phahame, o kanna oa hloka ho ba le tlhahlobo ea ALP isoenzyme. Teko ena e tla thusa ho tseba hore na ke karolo efe ea 'mele e bakang maemo a phahameng a ALP.

Teko ena e kanna ea sebelisoa ho fumana kapa ho lekola:

• Boloetse ba masapo
• Lefu la sebete, gallbladder, kapa bile
• Bohloko bo ka mpeng
• Boloetse ba lefu la parathyroid
• Khaello ea Vitamin D

Hape ho ka etsoa ho hlahloba tšebetso ea sebete le ho bona hore na meriana eo u e nkang e ka ama sebete sa hau joang.

Boleng bo tloaelehileng ba ALP e felletseng ke li-unit tsa machaba tsa 44 ho isa ho 147 ka litha e le nngwe (IU / L) kapa 0.73 ho isa ho 2.45 microkatal ka litara (atkat / L). Teko ea ALP isoenzyme e kanna ea ba le litekanyetso tse fapaneng tse tloaelehileng.

Batho ba baholo ba na le maemo a tlase a ALP ho feta bana. Masapo a ntseng a hola a hlahisa maemo a phahameng a ALP. Nakong ea kholo e itseng ea kholo, maemo a ka ba 500 IU / L kapa 835 µKat / L. Ka lebaka lena, tlhahlobo hangata ha e etsoe ho bana, 'me liphetho tse sa tloaelehang li bua ka batho ba baholo.

Liphetho tsa liteko tsa isoenzyme li ka senola hore na keketseho e ho "bone" ALP kapa "liver" ALP.

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.

Mohlala o kaholimo o bonts'a mefuta e tloaelehileng ea litekanyo bakeng sa liphetho tsa liteko tsena. Li laboratori tse ling li sebelisa litekanyo tse fapaneng kapa li ka leka mefuta e fapaneng.

Maemo a phahameng ho feta a tloaelehileng a ALP:

• Tšitiso ea biliary
• Boloetse ba masapo
• Ho ja lijo tse mafura haeba u na le mofuta oa mali O kapa B
• Ho fola ho robeha
• Lefu la sebete
• Hyperparathyroidism
• Lefuemia
• Lefu la sebete
• Lymphoma
• Lihlahala tsa masapo a Osteoblastic
• Osteomalacia
• Lefu la paget
• Li-rickets
• Sarcoidosis

Maemo a tlase ho feta a tloaelehileng a ALP:

• Hypophosphatasia
• Khaello ea phepo e nepahetseng
• Ho haella ha liprotheine
• Lefu la Wilson

Methati e phahame hanyane feela ho feta e tloaelehileng e kanna ea se be bothata ntle le haeba ho na le matšoao a mang a lefu kapa bothata ba bongaka.

Teko ea alkaline phosphatase isoenzyme

• Teko ea mali

PD ea Berk, Korenblat KM. Atamela mokuli ka liteko tsa jaundice kapa tse sa tloaelehang tsa sebete. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 147.

Fogel EL, Sherman S. Maloetse a senya le methapo ea bile. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 155.

Martin P. Ho atamela mokuli ea nang le lefu la sebete. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 146.

Rona ea Weinstein. Osteomalacia le rickets. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 244.