Cholinesterase - mali

Serum cholinesterase ke teko ea mali e shebileng maemo a lintho tse 2 tse thusang tsamaiso ea methapo ho sebetsa hantle. Li bitsoa acetylcholinesterase le pseudocholinesterase. Metsing ea hau e hloka lintho tsena ho romella lipontšo.

Acetylcholinesterase e fumanoa lisele tsa methapo le lisele tse khubelu tsa mali. Pseudocholinesterase e fumanoa haholo sebeteng.

Ho hlokahala sampole ea mali. Boholo ba nako mali a huloa mothapong o kahare ho setsoe kapa morao letsohong.

Ha ho mehato e ikhethileng e hlokahalang ho itokisetsa tlhahlobo ena.

U ka utloa bohloko bo bonyenyane kapa motsu ha nale e kentsoe. U kanna oa utloa ho phatloha hampe setšeng kamora hore mali a huloe.

Mofani oa hao oa tlhokomelo ea bophelo a ka laela tlhahlobo ena haeba o kile oa ba le likhemik'hale tse bitsoang organophosphates. Lik'hemik'hale tsena li sebelisoa ho chefo e bolaeang likokonyana. Teko ena e ka thusa ho fumana kotsi ea chefo.

Hangata, tlhahlobo ena e ka etsoa:

• Ho hlahloba lefu la sebete
• Pele o fumana anesthesia ka succinylcholine, e ka fanoang pele ho lits'ebetso tse ling kapa kalafo, ho kenyeletsoa le electroconvulsive therapy (ECT)

Ka tloaelo, litekanyetso tse tloaelehileng tsa pseudocholinesterase li pakeng tsa li-unit tse 8 ho isa ho tse 18 ka mililitara (U / mL) kapa li-kilouniti tse 8 le tse 18 ka litara (kU / L).

Tlhokomeliso: Mekhahlelo ea boleng bo tloaelehileng e ka fapana hanyane hara lilaboratori tse fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.

Ho fokotseha ha maemo a pseudocholinesterase ho ka bakoa ke:

• Tšoaetso e sa foleng
• Khaello ea phepo e sa foleng
• Lefu la pelo
• Tšenyo ea sebete
• Metastasis
• Jaundice e sitisang
• Chefo e tsoang ho organophosphates (lik'hemik'hale tse fumanoang ho tse ling tsa chefo e bolaeang likokonyana)
• Ho ruruha ho tsamaeang le mafu a mang

Ho fokotseha ho fokolang ho ka bakoa ke:

• Boimana
• Ts'ebeliso ea lipilisi tsa thibelo ea bokhachane

Acetylcholinesterase; RBC (kapa erythrocyte) cholinesterase; Pseudocholinesterase; Plasma cholinesterase; Butyrylcholinesterase; Serum cholinesterase

• Teko ea Cholinesterase

Aminoff MJ, Kahoo YT. Liphello tsa chefo le baemeli ba 'mele tsamaisong ea methapo. Ka: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, bahlophisi. Neurology ea Bradley ho Tloaelo ea Bongaka. La 7th. Philadelphia, PA: Elsevier; 2016: khaolo ea 86.

Nelson LS, Ford MD. Chefo e bohloko. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 110.