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Letsatsi La Creation: 27 Hlakubele 2021
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Teko ea mali ea Pyruvate kinase - Moriana
Teko ea mali ea Pyruvate kinase - Moriana

Teko ea pyruvate kinase e lekanya boemo ba enzyme pyruvate kinase maling.

Pyruvate kinase ke enzyme e fumanoang liseleng tse khubelu tsa mali. E thusa ho fetola tsoekere maling (glucose) ho matla ha maemo a oksijene a le tlase.

Ho hlokahala sampole ea mali. Ka laboratoring, lisele tse tšoeu tsa mali li tlosoa sampong ea mali hobane li ka fetola liphetho tsa liteko. Boemo ba pyruvate kinase boa lekanngoa.

Ha ho litokisetso tse khethehileng tse hlokahalang.

Haeba ngoana oa hau a etsa tlhahlobo ena, ho ka thusa ho hlalosa hore na tlhahlobo eo e tla ikutloa joang esita le ho bontša ka popi. Hlalosa lebaka la tlhahlobo. Ho tseba "joang hona hobaneng" ho ka fokotsa matšoenyeho a ngoana oa hau.

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ikutloa feela ho hlaba kapa ho hlaba. Kamora moo, ho ka ba le ho phatloha kapa ho longoa hanyane. Haufinyane sena sea fela.

Teko ena e etsoa ho fumana boemo bo tlase bo sa tloaelehang ba pyruvate kinase. Ntle le enzyme ena, lisele tse khubelu tsa mali li senyeha kapele ho feta tloaelo. Sena se bitsoa hemolytic anemia.


Teko ena e thusa ho fumana phumano ea pyruvate kinase (PKD).

Liphetho li fapana ho latela mokhoa oa liteko o sebelisitsoeng. Ka kakaretso, boleng bo tloaelehileng ke li-unit tsa 179 ± 16 ho 100 mL ea lisele tse khubelu tsa mali.

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li leka liteko tse fapaneng. Bua le mofani oa tlhokomelo ea bophelo mabapi le moelelo oa sephetho sa hau sa liteko.

Boemo bo tlase ba pyruvate kinase bo tiisa PKD.

Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho nka mali ho batho ba bang ho ka ba thata ho feta ho ba bang.

Likotsi tse ling tse amanang le ho huloa mali li nyane, empa li ka kenyelletsa:

  • Ho tsoa mali a mangata
  • Ho akheha kapa ho ikutloa o le hlooho e boima
  • Li-punctures tse ngata ho fumana methapo
  • Hematoma (mali a hahiloeng ka tlas'a letlalo)
  • Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Elghetany MT, Schexneider KI, mathata a Banki K. Erythrocytic. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 32.


Gallagher PG. Hemolytic anemias: lera le khubelu la sele le bofokoli ba metabolism. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 152.

Papachristodoulou D. metabolism ea matla. Ka: Naish J, Lekhotla la Syndercombe D, eds. Saense ea Bongaka. 3rd ed. Philadelphia, PA: Elsevier; 2019: khaolo ea 3.

van Solinge WW, van Wijk R. Li-enzyme tsa sele e khubelu ea mali. Ka: Rifai N, ed. Tietz ea Buka ea Khemistri ea Kliniki le Diagnostics ea Limolek'hule. La 6th. Philadelphia, PA: Elsevier; 2018: khaolo ea 30.

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