Cervical dysplasia

Cervical dysplasia e bolela liphetoho tse sa tloaelehang lisele tse ka holim'a molomo oa molomo. Sefuba sa molomo ke karolo e ka tlase ea popelo (popelo) e bulehang kaholimo ho botshehadi.

Liphetoho ha se mofets'e empa li ka lebisa ho mofetše oa molomo ha o sa alafshoe.

Cervical dysplasia e ka hlaha ka nako efe kapa efe. Leha ho le joalo, ho latela le kalafo ho tla latela lilemo tsa hau. Cervical dysplasia hangata e bakoa ke papillomavirus ea motho (HPV). HPV ke vaerase e tloaelehileng e fetisoang ka thobalano. Hona le mefuta e mengata ea HPV. Mefuta e meng e lebisa ho mokokotlo oa mokokotlo oa dysplasia kapa mofetše. Mefuta e meng ea HPV e ka baka lisosa tsa thobalano.

Lintho tse latelang li ka eketsa menyetla ea ho tšoaroa ke mokokotlo oa mokokotlo oa mokokotlo.

• Ho etsa thobalano pele ho lilemo tse 18
• Ho ba le ngoana a sa le monyane haholo
• Ho ba le baratuoa ba bangata ba thobalano
• Ho ba le mafu a mang, a kang lefuba kapa HIV
• Ho sebelisa meriana e hatellang sesole sa hau sa 'mele
• Ho tsuba
• Nalane ea bo-mme ea ho pepesehela DES (diethylstilbestrol)

Boholo ba nako, ha ho na matšoao.

Mofani oa hao oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea pelvic ho hlahloba mokokotlo oa mokokotlo oa dysplasia. Teko ea pele hangata ke ea Pap le teko ea boteng ba HPV.

Cervical dysplasia e bonoang tekong ea Pap e bitsoa squamous intraepithelial lesion (SIL). Tlalehong ea tlhahlobo ea Pap, liphetoho tsena li tla hlalosoa e le:

• Boemo bo tlase (LSIL)
• Boemo bo phahameng (HSIL)
• Mohlomong kankere (e kotsi)
• Lisele tse nang le litšoelesa tse tloaelehileng (AGC)
• Lisele tse tloaelehileng tsa squamous (ASC)

U tla hloka liteko tse ling haeba tlhahlobo ea Pap e bontša lisele tse sa tloaelehang kapa dysplasia ea mokokotlo. Haeba liphetoho li ne li le bobebe, liteko tsa Pap tse latelang e kanna ea ba sohle se hlokahalang.

Mofani oa thepa a ka etsa biopsy ho netefatsa boemo. Sena se ka etsoa ka ts'ebeliso ea colposcopy. Libaka life kapa life tse tšoenyang li tla biopsied. Li-biopsies li nyane haholo mme basali ba bangata ba ikutloa ba le cramp e nyane feela.

Dysplasia e bonoang ho biopsy ea molomo oa molomo e bitsoa cervical intraepithelial neoplasia (CIN). E arotsoe ka mekhahlelo e meraro:

• CIN I - dysplasia e bonolo
• CIN II - e leka-lekaneng ho tšoaea dysplasia
• CIN III - dysplasia e matla ho carcinoma in situ

Mefuta e meng ea HPV e tsejoa e baka mofetše oa popelo. Teko ea HPV DNA e ka supa mefuta e kotsing e kholo ea HPV e amanang le mofetše ona. Teko ena e kanna ea etsoa:

• E le tlhahlobo ea tlhahlobo ea basali ba fetang lilemo tse 30
• Bakeng sa basali ba lilemo life kapa life ba nang le sephetho se sa tloaelehang sa Pap

Kalafo e ipapisitse le boemo ba dysplasia. Dysplasia e bonolo (LSIL kapa CIN I) e ka tloha ntle le kalafo.

• U kanna oa hloka feela ho latela tlhaiso-leseling e hlokoang ke mofani oa hau ka ho pheta liteko tsa Pap likhoeli tse 6 ho isa ho tse 12.
• Haeba liphetoho li sa fele kapa li mpefala, ho hlokahala kalafo.

Kalafo ea dysplasia e matla ho ea ho e matla kapa e bonolo e sa tsamaeeng e ka kenyelletsa:

• Cryosurgery ho emisa lisele tse sa tloaelehang
• Phekolo ea Laser, e sebelisang leseli ho chesa lisele tse sa tloaelehang
• LEEP (loop electrosurgical excision procedure), e sebelisang motlakase ho tlosa lisele tse sa tloaelehang
• Ho buoa ho tlosa lisele tse sa tloaelehang (cone biopsy)
• Hysterectomy (maemong a sa tloaelehang)

Haeba u kile ua ba le dysplasia, u tla hloka ho pheta litlhahlobo likhoeling tse ling le tse ling tse 12 kapa joalokaha mofani oa hau a khothalelitse.

Etsa bonnete ba hore o fumana ente ea HPV ha u e fuoa. Vaksine ena e thibela mefuta e mengata ea mofetše oa popelo.

Ho fumanoa kapele le kalafo e potlakileng ho phekola maemo a mangata a mokokotlo oa lefu la mokokotlo. Leha ho le joalo, boemo bo ka khutla.

Ntle le kalafo, lefu la mokokotlo le ka fetoha mofetše oa popelo.

Bitsa mofani oa hau haeba lilemo tsa hau li le 21 kapa ho feta 'me ha u e-so hlahlojoe pelvic le Pap.

Botsa mofani oa hau ka vaksine ea HPV. Banana ba fumanang ente ena pele ba kena thobalanong ba fokotsa menyetla ea ho tšoaroa ke mofetše oa popelo.

U ka fokotsa menyetla ea ho ba le lefu la mokokotlo ka ho nka mehato e latelang:

• Fumana ente bakeng sa HPV pakeng tsa lilemo tse 9 ho isa ho tse 45.
• Se ke oa tsuba. Ho tsuba ho eketsa menyetla ea ho ba le dysplasia e matla le mofetše.
• Se ke oa etsa thobalano ho fihlela u le lilemo li 18 kapa ho feta.
• Itloaetse ho etsa thobalano e sireletsehileng. Sebelisa khohlopo.
• Itloaetse ho nyala mosali a le mong. Sena se bolela hore o na le molekane a le mong feela oa thobalano ka nako e le ngoe.

Mokokotlo intraepithelial neoplasia - dysplasia; CIN - dysplasia; Liphetoho tsa pelehi tsa popelo - dysplasia; Kankere ea mokokotlo - dysplasia; Squamous intraepithelial leqeba - dysplasia; LSIL - dysplasia; HSIL - dysplasia; Dysplasia ea maemo a tlase; Dysplasia ea boemo bo phahameng; Carcinoma in situ - dysplasia; CIS - dysplasia; ASCUS - dysplasia; Lisele tse sa tloaelehang tsa glandular - dysplasia; AGUS - dysplasia; Lisele tse tloaelehileng tsa squamous - dysplasia; Pap smear - dysplasia; HPV - dysplasia; Kokoana-hloko ea motho ea papilloma - dysplasia; Sefuba - dysplasia; Colposcopy - dysplasia

• Anatomy ea basali ea ho ikatisa
• Neoplasia ea mokokotlo
• Sebete
• Cervical dysplasia - letoto la lihlooho tse

Koleji ea Amerika ea Litsebi tsa Litsebi le Lingaka tsa Gynecologists. Itloaetse Bulletin No. 168: Ho hlahloba le ho thibela mofetše oa popelo. Gynecol e thibelang. 2016; 128 (4): e111-e130. PMID: 27661651 e fetotsoe.ncbi.nlm.nih.gov/27661651/.

Koleji ea Amerika ea Litsebi tsa Litsebi le Lingaka tsa Gynecologists. Itloaetse Bulletin No. 140: taolo ea sephetho se sa tloaelehang sa liteko tsa tlhahlobo ea mofetše oa popelo le tse tlang pele ho mofetše oa popelo. Gynecol e thibelang. 2013; 122 (6): 1338-1367. PMID: 24264713 pubmed.ncbi.nlm.nih.gov/24264713/.

Armstrong DK. Kankere ea mafu a basali. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 189.

Freedman MS, Hunter P, Ault K, Kroger A. Komiti ea Boeletsi ea Mekhoa ea Thibelo ea Thibelo e khothalelitse kemiso ea ente bakeng sa batho ba baholo ba lilemo li 19 kapa ho feta - United States, 2020. MMWR Morb Mortal Wkly Rep. 2020; 69 (5): 133-135. PMID: 32027627 e fetotsoe.ncbi.nlm.nih.gov/32027627/.

Hacker NF. Cervical dysplasia le mofetše. Ka: Hacker NF, Gambone JC, Hobel CJ, eds. Hacker & Moore's Essentials of Obstetrics and Gynaecology. La 6th. Philadelphia, PA: Elsevier; 2016: khaolo ea 38.

Sehlopha sa Mosebetsi sa Setsebi sa Thibelo ea Bokooa, Komiti ea Tlhokomelo ea Bophelo ba Bacha. Maikutlo a Komiti No. 704: ente ea papillomavirus ea motho. Gynecol e thibelang. 2017; 129 (6): e173-e178. PMID: 28346275 phatlalalitsoe.ncbi.nlm.nih.gov/28346275/.

Robinson CL, Bernstein H, Poehling K, Romero JR, Szilagyi P.Komiti ea Boeletsi ea Mekhoa ea Thibelo ea Thibelo e khothalletsa kemiso ea ente bakeng sa bana le bacha ba lilemo li 18 kapa tlase - United States, 2020. MMWR Morb Mortal Wkly Rep. 2020; 69 (5): 130-132. PMID: 32027628 phatlalalitsoeng.ncbi.nlm.nih.gov/32027628/.

MP ea Salcedo, Baker ES, Schmeler KM. Intraepithelial neoplasia ea pampiri e ka tlase ea thobalano (molomo, setho sa botšehali, botšehali): etiology, ho hlahloba, ho hlahloba le ho laola. Ka: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Kakaretso ea mafu a basali. La 7th. Philadelphia, PA: Elsevier; 2017: khaolo ea 28.

Saslow D, Solomon D, Lawson HW, le al; Komiti ea Tataiso ea ACS-ASCCP-ASCP ea Cervical Cancer. American Cancer Society, American Society for Colposcopy and Cervical Pathology, le American Society for Clinical Pathology litlhahlobo tsa thibelo le ho sibolla kankere ea popelo kapele. CA Kankere J Clin. 2012; 62 (3): 147-172. PMID: 22422631 e fetotsoe.ncbi.nlm.nih.gov/22422631/.

Sesole sa Ts'ireletso sa US, Curry SJ, Krist AH, Owens DK, et al. Ho hlahloba kankere ea popelo: Polelo ea khothaletso ea Sesole sa Ts'ireletso ea US. JAMA. 2018; 320 (7): 674-686. PMID: 30140884 e fetotsoe.ncbi.nlm.nih.gov/30140884/.