Khaello ea Congenital antithrombin III

Ho haelloa ke lefu la antithrombin III ke lefu la lefutso le etsang hore mali a koalehe ho feta se tloaelehileng.

Antithrombin III ke protheine e maling e thibelang mali hore a se ke a hlaha. E thusa 'mele ho boloka botsitso bo nepahetseng lipakeng tsa ho tsoa mali le hoama. Khaello ea Congenital antithrombin III ke lefu le futsitsoeng. E etsahala ha motho a amohela kopi e le 'ngoe e sa tloaelehang ea lefutso la antithrombin III ho motsoali ea nang le lefu lena.

Jini e sa tloaelehang e lebisa boemong bo tlase ba protheine ea antithrombin III. Boemo bona bo tlase ba antithrombin III bo ka baka maqeba a sa tloaelehang a mali (thrombi) a ka thibelang phallo ea mali le ho senya litho tsa mmele.

Batho ba nang le boemo bona hangata ba tla ba le tšelo ea mali ba sa le banyenyane. Ba kanna ba ba le litho tsa malapa tse bileng le bothata ba ho hoama mali.

Hangata batho ba tla ba le matšoao a lefu la mali. Ho koala mali matsohong kapa maotong hangata ho baka ho ruruha, bofubelu le bohloko. Ha leqeba la mali le khaoha moo le thehileng mme le ea karolong e 'ngoe ea' mele, le bitsoa thromboembolism. Matšoao a ipapisitse le hore na leqhoa la mali le ea kae. Sebaka se tloaelehileng ke matšoafo, moo lesela le ka bakang khohlela, phefumoloho e khuts'oane, bohloko ha o ntse o hema haholo, bohloko ba sefuba esita le lefu. Ho koala mali ho ea bokong ho ka baka setorouku.

Tlhahlobo ea 'mele e ka bonts'a:

• Leoto kapa letsoho le ruruhileng
• Ho fokotseha ha phefumoloho ho utloahala matšoafong
• Ho otla ha pelo ka potlako

Mofani oa tlhokomelo ea bophelo a ka laela hore tlhahlobo ea mali e hlahlojoe hore na o na le antithrombin III e tlase.

Lefu la mali le phekoloa ka meriana e fokotsang mali (eo hape e bitsoang li-anticoagulants). U hloka ho nka lithethefatsi tsena nako e kae ho latela hore na leqhoa la mali le tebile hakae le lintlha tse ling. Buisanang ka sena le mofani oa thepa ea hau.

Lisebelisoa tsena li ka fana ka tlhaiso-leseling e batsi ka tlhaelo ea congenital antithrombin III:

• Mokhatlo oa Naha oa Mathata a Rare - rarediseases.org/rare-diseases/antithrombin-deficiency
• Referense ea Lehae la NLM Genetics - ghr.nlm.nih.gov/condition/hereditary-antithrombin-deficiency

Batho ba bangata ba na le litholoana tse ntle haeba ba lula litlhare tsa anticoagulant.

Ho koala mali ho ka baka lefu. Ho koala mali matšoafong ho kotsi haholo.

Bona mofani oa hau haeba u na le matšoao a boemo bona.

Hang ha motho a fumanoa a na le khaello ea antithrombin III, litho tsohle tsa lelapa tse haufi li lokela ho hlahlojoa lefu lena. Lithethefatsi tse fokotsang mali li ka thibela maqeba a mali ho theha le ho thibela mathata hore a se ke a hoama.

Khaello - antithrombin III - tsoalo; Ho haelloa ke Antithrombin III - ho tsoaloa

• Lefu la mali la mali

Anderson JA, Hogg KE, Weitz JI. Linaha tse nang le khatello ea mali. Ka: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Melao-motheo le Tloaelo ea Motheo. La 7th. Philadelphia, PA: Elsevier Saunders; 2018: khaolo ea 140.

AI Schafer. Mathata a Thrombotic: linaha tse haelloang ke mali. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 176.