Lefu la lebese-alkali

Lebese-alkali syndrome ke boemo boo ho lona ho nang le boemo bo phahameng ba calcium 'meleng (hypercalcemia). Sena se baka phetoho ea 'mele ea acid / base ho ea ho alkaline (metabolism ea metabolism). Ka lebaka leo, ho ka ba le tahlehelo ea ts'ebetso ea liphio.

Lefu la lebese-alkali hangata le bakoa ke ho nka li-calcium tse ngata haholo, hangata e le calcium carbonate. Calcium carbonate ke tlatsetso e tloaelehileng ea calcium. Hangata ho nkoa ho thibela kapa ho phekola tahlehelo ea masapo (osteoporosis). Calcium carbonate le eona ke motsoako o fumanoang li-antacids (joalo ka li-Tums).

Boemo bo phahameng ba vithamine D 'meleng, joalo ka ho noa li-supplement, bo ka mpefatsa lefu la lebese-alkali.

Li-calcium tse kenang liphio le lisele tse ling li ka hlaha ka lefu la lebese-alkali.

Qalong, boemo bona hangata ha bo na matšoao (asymptomatic). Ha matšoao a hlaha, a ka kenyelletsa:

• Ka morao, bohareng ba 'mele, le mahlaba a tlase mokokotlong sebakeng sa liphio (se amanang le majoe a liphio)
• Pherekano, boitšoaro bo makatsang
• Ho sokela
• Ho tepella maikutlo
• Ho ntša metsi haholo
• Mokhathala
• Ho otla ha pelo ka mokhoa o sa tloaelehang (arrhythmia)
• Ho nyekeloa kapa ho hlatsa
• Mathata a mang a ka bakoang ke ho hloleha ha liphio

Li-calcium tse kenang ka har'a lisele tsa liphio (nephrocalcinosis) li ka bonoa ho:

• Li-X-ray
• CT scan
• Ultrasound

Liteko tse ling tse sebelisetsoang ho hlahloba li ka kenyelletsa:

• Methati ea Electrolyte ho lekola maemo a diminerale 'meleng
• Electrocardiogram (ECG) ho lekola tšebetso ea motlakase ea pelo
• Electroencephalogram (EEG) ho lekanya tšebetso ea motlakase bokong
• Sekhahla sa filtration ea Glomerular (GFR) ho hlahloba hore na liphio li sebetsa hantle hakae
• Tekanyo ea calcium ea mali

Maemong a boima, kalafo e kenyelletsa ho fana ka maro ka mothapo (ka IV). Ho seng joalo, kalafo e kenyelletsa ho noa maro hammoho le ho fokotsa kapa ho emisa li-supplement tsa calcium le li-antacids tse nang le calcium. Lisebelisoa tsa vithamine D le tsona li hloka ho fokotsoa kapa ho emisoa.

Boemo bona hangata bo ka khutlisoa haeba ts'ebetso ea liphio e lula e le ntho e tloaelehileng. Maemo a matla a nako e telele a ka lebisa ho hloleha ho sa feleng ha liphio ho hloka dialysis.

Mathata a atileng haholo a kenyelletsa:

• Calcium e kenya lisele (calcinosis)
• Ho hloleha ha liphio
• Majoe a liphio

Ikopanye le mofani oa tlhokomelo ea bophelo haeba:

• U nka li-calcium tse ngata kapa hangata u sebelisa li-antacids tse nang le calcium, joalo ka Tums. U kanna ua hloka ho hlahlojoa bakeng sa lefu la alkali ea lebese.
• U na le matšoao a ka supang mathata a liphio.

Haeba u sebelisa li-antacids tse nang le calcium khafetsa, bolella mofani oa hau ka mathata a silang lijo. Haeba o leka ho thibela lefu la masapo, se ke oa nka ligrama tse fetang 1,2 (1200 milligrams) tsa calcium ka letsatsi ntle le haeba mofani oa litšebeletso a laetse.

Lefu la calcium-alkali; Lefu la Cope; Lefu la Burnett; Hypercalcemia; Mathata a calcium metabolism

Tlisahurhur FR, Demay MB, Kronenberg HM. Li-hormone le mathata a metabolism ea diminerale. Ka: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, bahlophisi. Buka ea Williams ea Endocrinology. La bo14 la ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 29.

DuBose TD. Metabolical alkalosis. Ka: Gilbert SJ, Weiner DE, bahlophisi. Setsi sa Naha sa Liphio. La 7th. Philadelphia, PA: Elsevier; 2018: khaolo ea 14.