Glucagonoma

Glucagonoma ke hlahala e sa tloaelehang haholo ea lisele tsa sehlekehleke sa manyeme, e lebisang ho fetelleng ha hormone ea glucagon maling.

Glucagonoma hangata e na le mofetše (e bohloko). Kankere e atisa ho ata le ho mpefala.

Kankere ena e ama lisele tsa sehlekehleke sa manyeme. Ka lebaka leo, lisele tsa sehlekehleke se hlahisa hormone ea glucagon e ngata haholo.

Lebaka ha le tsejoe. Lintho tsa lefutso li nka karolo maemong a mang. Nalane ea lelapa ea lefu lena la mofuta oa endocrine neoplasia mofuta oa I (MEN I) ke sesosa sa kotsi.

Matšoao a glucagonoma a kenyeletsa tse latelang:

• Ho hloka mamello ea glucose ('mele o na le bothata ba ho senya tsoekere)
• Tsoekere e phahameng maling (hyperglycemia)
• Letšollo
• Lenyora le feteletseng (ka lebaka la tsoekere e phahameng maling)
• Ho rota khafetsa (ka lebaka la tsoekere e phahameng maling)
• Ho eketsa takatso ea lijo
• Molomo le leleme le ruruhileng
• Ho rota bosiu (bosiu)
• Ho phatloha ha letlalo sefahlehong, mpeng, marameng, kapa maotong ho kenang le ho tsamaea
• Ho fokotsa boima ba 'mele

Maemong a mangata, mofets'e o se o nametse sebeteng ha o fumanoa.

Mofani oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele' me a botse nalane le matšoao a hau a bongaka.

Liteko tse ka etsoang li kenyelletsa:

• CT scan ea mpa
• Tekanyo ea glucagon maling
• Tekanyo ea tsoekere maling

Hangata ho buelloa ho buoa ho tlosa hlahala. Hangata hlahala ha e arabele chemotherapy.

U ka fokotsa khatello ea maikutlo ea bokuli ka ho kenela sehlopha sa ts'ehetso ea mofets'e. Ho arolelana le ba bang ba nang le liphihlelo tse tšoanang le mathata ho ka u thusa hore u se ke ua ikutloa u le mong.

Hoo e ka bang 60% ea lihlahala tsena li na le mofetše. Ho tloaelehile hore mofetše ona o namele sebeteng. Ke batho ba ka bang 20% ​​feela ba ka folisoang ka ho buuoa.

Haeba hlahala e le manyeme feela mme ho buuoa ho e ntša ho atlehile, batho ba na le pholoho ea lilemo tse 5 ea 85%.

Kankere e ka namela sebeteng. Tekanyo e phahameng ea tsoekere maling e ka baka mathata ka metabolism le tšenyo ea lisele.

Bitsa mofani oa hau haeba u bona matšoao a glucagonoma.

BANNA I - glucagonoma

• Litšoelesa tsa endocrine

Webosaete ea National Cancer Institute. Pancreatic neuroendocrine tumors (islet cell tumors) kalafo (PDQ) - mofuta oa litsebi tsa bophelo bo botle. www.cancer.gov/types/pancreatic/hp/pnet-tlhare-pdq. E ntlafalitsoe ka la 8 Hlakola 2018. E fihlile ka la 12 Pulungoana 2018.

Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Kankere ea sistimi ea endocrine. Ka: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, bahlophisi. Abeloff's Clinical Oncology. La 5th. Philadelphia, PA: Elsevier Saunders; 2014: khaolo ea 71.

Vella A. Lihormone tsa ka mpeng le lihlahala tsa endocrine. Ka: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, bahlophisi. Buka ea Williams ea Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: khaolo ea 38.