VIPoma

VIPoma ke mofetše o sa tloaelehang haholo o atisang ho hola ho tloha liseleng tsa manyeme tse bitsoang li-islet cell.

VIPoma e etsa hore lisele tsa manyeme li hlahise lihormone tse phahameng tse bitsoang vasoactive intestinal peptide (VIP). Hormone ena e eketsa liphiri tse tsoang mala. E boetse e khatholla e meng ea mesifa e boreleli tsamaisong ea meno.

Lebaka le tobileng la VIPomas ha le tsejoe.

Hangata li-VIPomas li fumanoa ho batho ba baholo, hangata li ka ba lilemo li 50. Basali ba kotsing ea ho ameha ho feta banna. Kankere ena e fumaneha seoelo. Selemo se seng le se seng, ke batho ba ka bang limilione tse 10 feela ba fumanoang ba na le VIPoma.

Matšoao a VIPoma a ka kenyelletsa efe kapa efe ea tse latelang:

• Bohloko ba mpeng le ho peperana
• Letšollo (metsi, mme hangata ka bongata)
• Ho felloa ke metsi 'meleng
• Ho ruruha kapa bokgubedu ba sefahleho
• Maqhubu a mesifa ka lebaka la potasiamo e tlase ea mali (hypokalemia)
• Ho nyekeloa
• Ho fokotsa boima ba 'mele

Mofani oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele' me a botse nalane le matšoao a hau a bongaka.

Liteko tse ka etsoang li kenyelletsa:

• Liteko tsa chemistry ea mali (phanele ea mantlha kapa e phethahetseng ea metabolic)
• CT scan ea mpa
• MRI ea mpa
• Ho hlahloba setuloana ka lebaka la lets'ollo le maemo a elektrolyte
• Boemo ba VIP maling

Morero oa pele oa kalafo ke ho lokisa ho felloa ke metsi 'meleng. Maro a mangata a fanoa ka mothapo (maro a kenang methapong) ho nkela maro a lahlehileng ke letshollo.

Morero o latelang ke ho fokotsa letšollo. Meriana e ka thusa ho laola lets'ollo. E 'ngoe ea meriana e joalo ke octreotide. Ke mofuta o entsoeng ke motho oa hormone ea tlhaho e thibelang ketso ea VIP.

Monyetla o motle oa pheko ke ho buuoa ho tlosa hlahala. Haeba hlahala e sa namela lithong tse ling, hangata ho buuoa ho ka phekola boemo.

U ka fokotsa khatello ea maikutlo ea bokuli ka ho kenela sehlopha sa ts'ehetso ea mofets'e. Ho arolelana le ba bang ba nang le liphihlelo tse tšoanang le mathata ho ka u thusa hore u se ke ua ikutloa u le mong.

Phekolo hangata e ka phekola li-VIPomas. Empa, karolong ea boraro ho isa ho halofo ea batho, hlahala e hasane ka nako ea tlhahlobo mme e ke ke ea phekoloa.

Mathata a ka kenyelletsa:

• Kankere e hasana (metastasis)
• Ho tšoaroa ha pelo ho tloha maemong a tlase a potasiamo ea mali
• Ho felloa ke metsi 'meleng

Haeba u na le letšollo le nang le metsi matsatsi a fetang a mabeli ho isa ho a mararo, letsetsa mofani oa litšebeletso.

Hlahala e hlahisang Vasoactive ea mala a peptide; Lefu la VIPoma; Pancreatic endocrine hlahala

• Mekhanya

Webosaete ea National Cancer Institute. Pancreatic neuroendocrine tumors (islet cell tumors) kalafo (PDQ) - mofuta oa litsebi tsa bophelo bo botle. www.cancer.gov/types/pancreatic/hp/pnet-tlhare-pdq. E ntlafalitsoe ka la 8 Hlakola 2018. E fihlile ka la 12 Pulungoana 2018.

Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Kankere ea sistimi ea endocrine. Ka: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, bahlophisi. Abeloff's Clinical Oncology. La 5th. Philadelphia, PA: Elsevier Saunders; 2014: khaolo ea 71.

Vella A. Lihormone tsa ka mpeng le lihlahala tsa endocrine. Ka: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, bahlophisi. Buka ea Williams ea Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: khaolo ea 38.