Teko ea Thyroxine (T4)
Litaba
- Teko ea thyroxine (T4) ke eng?
- E sebelisetsoa eng?
- Hobaneng ha ke hloka teko ea thyroxine?
- Ho etsahalang nakong ea teko ea thyroxine?
- Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
- Na ho na le likotsi tsa tlhahlobo?
- Liphetho li bolelang?
- Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea thyroxine?
- Litšupiso
Teko ea thyroxine (T4) ke eng?
Teko ea thyroxine e thusa ho fumana mathata a qoqotho. Thyroid ke tšoelesa e nyane e bopehileng joaloka serurubele e haufi le 'metso. Thyroid ea hao e etsa lihomone tse laolang tsela eo 'mele oa hao o sebelisang matla ka eona. E boetse e bapala karolo ea bohlokoa ho laoleng boima ba 'mele oa hau, mocheso oa' mele, matla a mesifa esita le maikutlo a hau. Thyroxine, e tsejoang hape e le T4, ke mofuta oa hormone ea qoqotho. Tlhahlobo ena e lekanya boemo ba T4 maling a hao. T4 e ngata haholo kapa e nyane haholo e ka supa lefu la qoqotho.
Hormone ea T4 e hlaha ka mefuta e 'meli:
- T4 ea mahala, e kenang liseleng tsa 'mele moo e hlokahalang
- Ho koaheloa T4, e khomarelang liprotheine, e li sitisang ho kena lisele tsa 'mele
Teko e lekanyang T4 ea mahala le e tlamiloeng e bitsoa tlhahlobo ea T4 ka botlalo. Liteko tse ling li lekanya T4 ea mahala feela. Teko ea mahala ea T4 e nkuoa e nepahetse ho feta tlhahlobo e felletseng ea T4 bakeng sa ho lekola tšebetso ea qoqotho.
Mabitso a mang: thyroxine ea mahala, mahala T4, kakaretso ea T4, skrine ea thyroxine, mohopolo oa mahala oa T4
E sebelisetsoa eng?
Teko ea T4 e sebelisetsoa ho lekola ts'ebetso ea qoqotho le ho fumana lefu la qoqotho.
Hobaneng ha ke hloka teko ea thyroxine?
Lefu la qoqotho le atile haholo ho basali 'me hangata le hlaha ba le ka tlase ho lilemo tse 40. Le boetse le sebetsa malapeng. U kanna ua hloka tlhahlobo ea thyroxine haeba setho sa lelapa se kile sa tšoaroa ke lefu la qoqotho kapa haeba u na le matšoao a ho ba le lihomone tse ngata tsa qoqotho maling a hao, boemo bo bitsoang hyperthyroidism, kapa matšoao a ho ba le "hormone" e fokolang ea "thyroid", e bitsoang hypothyroidism.
Matšoao a hyperthyroidism, a tsejoang hape e le thyroid e feteletseng, a kenyelletsa:
- Ho tšoenyeha
- Ho fokotsa boima ba 'mele
- Ho thothomela matsohong
- Ho eketseha ha lebelo la pelo
- Boikhohomoso
- Ho phatloha ha mahlo
- Mathata a ho robala
Matšoao a hypothyroidism, a tsejoang hape e le qoqotho e sa sebetseng, a kenyelletsa:
- Boima ba 'mele
- Mokhathala
- Ho hlotheha ha moriri
- Mamello e tlase bakeng sa mocheso o batang
- Linako tse sa tloaelehang tsa ho ilela khoeli
- Ho sokela
Ho etsahalang nakong ea teko ea thyroxine?
Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.
Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea mali ea thyroxine. Haeba mofani oa hao oa tlhokomelo ea bophelo a laetse liteko tse ling sampoleng ea mali a hau, ho ka hlokahala hore u itime lijo (u se ke ua ja kapa oa noa) lihora tse 'maloa pele ho tlhahlobo. Mofani oa hao oa tlhokomelo ea bophelo o tla u tsebisa haeba ho na le litaelo tse khethehileng tseo u lokelang ho li latela.
Na ho na le likotsi tsa tlhahlobo?
Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.
Liphetho li bolelang?
Liphetho tsa hau li ka tla ka mofuta oa kakaretso ea T4, mahala T4, kapa index ea mahala ea T4.
- Lenane la mahala la T4 le kenyelletsa foromo e bapisang mahala le tlamo ea T4.
- Maemo a phahameng a efe kapa efe ea liteko tsena (kakaretso ea T4, mahala T4, kapa index ea mahala ea T4) a ka supa thyroid e fetelletseng, e tsejoang hape e le hyperthyroidism.
- Maemo a tlase a liteko tsena (kakaretso ea T4, mahala T4, kapa index ea mahala ea T4) a ka supa qoqotho e sa sebetseng, e tsejoang hape e le hypothyroidism.
Haeba sephetho sa hau sa tlhahlobo ea T4 se sa tloaeleha, mofani oa tlhokomelo ea bophelo o kanna a laela liteko tse ling tsa qoqotho ho u thusa ho fumana hore na o na le eng. Tsena li ka kenyelletsa:
- Liteko tsa lihormone tsa T3. T3 ke hormone e 'ngoe e entsoeng ke qoqotho.
- Tlhahlobo ea TSH (thyroid stimulating hormone). TSH ke hormone e entsoeng ke tšoelesa ea pituitary. E etsa hore thyroid e hlahise lihomone tsa T4 le T3.
- Liteko tsa ho fumana lefu la Graves, lefu le ikemetseng le bakang hyperthyroidism
- Liteko tsa ho fumana Hashimoto's thyroiditis, lefu le ikemetseng le bakang hypothyroidism
Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.
Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea thyroxine?
Liphetoho tsa qoqotho li ka etsahala nakong ea bokhachane. Le ha ho sa tloaeleha, basali ba bang ba ka ba le lefu la qoqotho nakong ea bokhachane. Hyperthyroidism e etsahala ka karolo ea 0,1 ho isa ho 0,4 lekholong ea bokhachane, ha hypothyroidism e etsahala ho basali ba ka bang 2,5% ea bokhachane.
Hyperthyroidism, mme hangata, hypothyroidism, e ka sala kamora ho ima. Haeba u ba le boemo ba qoqotho nakong ea bokhachane, mofani oa hao oa tlhokomelo ea bophelo o tla beha leihlo boemo ba hau kamora hore ngoana a hlahe. Hape, haeba u na le nalane ea lefu la qoqotho, etsa bonnete ba hore u bua le mofani oa tlhokomelo ea bophelo haeba u imme kapa u nahana ho ima.
Litšupiso
- Mokhatlo oa Amerika oa qoqotho [Inthanete]. Kereke ea Falls (VA): Mokhatlo oa Amerika oa Thyroid; c2017. Liteko tsa Mosebetsi oa Thyroid [e qotsitsoeng ka 2017 Mots'eanong 22]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.thyroid.org/thyroid-function-tests
- Hinkle J, Cheever K. Brunner & Suddarth's Handbook ea Liteko tsa Laboraro le Tlhatlhobo. 2ke Monghali, Kindle. Philadelphia: Wolters Kluwer Bophelo, Lippincott Williams & Wilkins; c2014. Thryoxine, Serum 485 leq.
- Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2017. T4 ea mahala: Teko [e ntlafalitsoeng 2014 Oct 16; e qotsitsoeng ka 2017 Mots'eanong 22]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://labtestsonline.org/understanding/analytes/t4/tab/test
- Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2017. T4 ea mahala: Sampole ea Teko [e ntlafalitsoeng 2014 Oct 16; e qotsitsoeng ka 2017 Mots'eanong 22]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/understanding/analytes/t4/tab/sample
- Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2017. TSH: Mohlala oa Teko [o ntlafalitsoeng 2014 Oct 15; e qotsitsoeng ka 2017 Mots'eanong 22]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/understanding/analytes/tsh/tab/sample
- Phetolelo ea Merck Manual Consumer [Inthanete]. Kenilworth (NJ): Merck & Co Inc .; c2017. Kakaretso ea Thyroid Gland [e qotsitsoeng ka 2017 Mots'eanong 22]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/thyroid-gland-disorders/overview-of-the-thyroid-gland
- Setsi sa Naha sa Lefu la Ts'oaetso le Mafu a Ts'oaetso le Liphio [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Lefu la Mabitla; 2012 Aug [e qotsitsoeng ka la 2017 Mots'eanong 22]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.niddk.nih.gov/health-information/endocrine-diseases/graves-disease
- Setsi sa Naha sa Lefu la Ts'oaetso le Mafu a Ts'oaetso le Liphio [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Lefu la Hashimoto; 2014 Mots'eanong [e qotsitsoeng ka la 2017 Mots'eanong 22]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease
- Setsi sa Naha sa Lefu la Ts'oaetso le Mafu a Ts'oaetso le Liphio [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa qoqotho; 2014 Mots'eanong [e qotsitsoeng ka la 2017 Mots'eanong 22]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.niddk.nih.gov/health-information/diagnostic-tests/thyroid
- National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Likotsi Tsa Liteko Tsa Mali ke Life? [e ntlafalitsoeng 2012 Jan 6; e qotsitsoeng ka 2017 Mots'eanong 22]; [li-skrini tse ka bang 5]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
- National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Seo U ka se Lebellang ka Liteko tsa Mali [e ntlafalitsoeng ka 2012 Pherekhong 6; e qotsitsoeng ka 2017 Mots'eanong 22]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
- Soldin OP. Teko ea Mosebetsi oa Thyroid Boimana le Maloetse a Thyroid: Likarolo tse ikhethileng tsa Referense. Ther Lithethefatsi Monit. [Inthanete]. 2006 Feb [e qotsitsoeng 2019 Jun 3]; 28 (1): 8-11. E fumaneha ho tsoa ho: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625634
- Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2017. Health Encyclopedia: Free and Bound T4 [e qotsitsoeng ka 2017 Mots'eanong 22]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=t4_free_and_bound_blood
- Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2017. Health Encyclopedia: Free T4 [e qotsitsoeng ka la 2017 Mphalane 22]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=free_t4_thyroxine
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