Sengoli: Peter Berry
Letsatsi La Creation: 11 Phupu 2021
Ntlafatsa Letsatsi: 1 November 2024
Anonim
Ho phekola Multiple Sclerosis Flare-Ups ka li-Steroid - Bophelo
Ho phekola Multiple Sclerosis Flare-Ups ka li-Steroid - Bophelo

Litaba

Li-steroids li sebelisoa joang ho phekola MS

Haeba u na le multiple sclerosis (MS), ngaka ea hau e ka 'na ea fana ka corticosteroids ho phekola liketsahalo tsa maloetse tse bitsoang exacerbations. Likarolo tsena tsa matšoao a macha kapa a khutlang li boetse li tsejoa e le litlhaselo, ho phatloha kapa ho khutlela morao.

Li-steroid li etselitsoe ho khutsufatsa tlhaselo hore o tle o boele tseleng kapele.

Ha ho hlokahale ho phekola li-MS tsohle hape ka li-steroids. Hangata meriana ena e boloketsoe ho khutlela morao haholo ho sitisang bokhoni ba hau ba ho sebetsa. Mehlala e meng ea sena ke bofokoli bo matla, litaba tsa teka-tekano, kapa pherekano ea pono.

Kalafo ea steroid e matla 'me e ka baka litla-morao tse fapaneng ho ea ka batho. Kalafo ea methapo (IV) ea steroid e ka ba theko e boima ebile e sa ba bonolo.

Melemo le likotsi tsa li-steroid bakeng sa MS li tlameha ho lekanyetsoa ka bomong mme li ka fetoha nakong ea lefu lena.

Tsoela pele ho bala ho ithuta haholoanyane ka li-steroids tsa MS le melemo ea tsona le litlamorao tsa tsona.


Multiple sclerosis steroids

Mofuta oa li-steroid tse sebelisetsoang MS o bitsoa glucocorticoids. Meriana ena e etsisa phello ea lihomone tseo 'mele oa hau o li hlahisang ka tlhaho.

Ba sebetsa ka ho koala tšitiso e sa sebetseng ea mali le bokong, e thusang ho emisa lisele tsa ho ruruha hore li se fallele tsamaisong ea methapo e bohareng. Sena se thusa ho thibela ho ruruha le ho nolofatsa matšoao a MS.

Hangata li-steroids tse phahameng li fuoa methapo hang ka letsatsi matsatsi a mararo ho isa ho a mahlano. Sena se tlameha ho etsoa tleliniking kapa sepetlele, hangata kantle ho bakuli ba kantle. Haeba u na le mathata a tebileng a bophelo bo botle, ho ka hlokahala hore u kene sepetlele.

Kalafo ea IV ka linako tse ling e lateloa ke li-steroids tsa molomo ka beke e le 'ngoe kapa tse peli, nakong eo lethal dose le fokotsehang butle. Maemong a mang, li-steroids tsa molomo li nkuoa libeke tse tšeletseng.

Ha ho na litekanyetso kapa litekanyetso tse tloaelehileng bakeng sa kalafo ea steroid bakeng sa MS. Ngaka ea hau e tla hlokomela ho tiea ha matšoao a hau mme e kanna ea batla ho qala ka lethal dose e tlase ka ho fetisisa.


Tse latelang ke tse ling tsa li-steroid tse sebelisetsoang ho phekola ho khutlela morao ha MS.

Solumedrol

Solumedrol, steroid e atisang ho sebelisoa ho phekola MS, ke lebitso la methylprednisolone. E matla haholo 'me hangata e sebelisetsoa ho khutlela morao haholo.

Mefuta e tloaelehileng ea li-dosing e tloha ho limiligrama tse 500 ho isa ho tse 1000 ka letsatsi. Haeba u e-na le 'mele o monyane, tekanyetso e ka tlase ea sekala e ka mamelleha haholoanyane.

Solumedrol e tsamaisoa ka methapo setsing sa infusion kapa sepetlele. Infusion e ngoe le e ngoe e nka hora, empa sena se ka fapana. Nakong ea infusion, o kanna oa hlokomela tatso ea tšepe molomong oa hau, empa ke ea nakoana.

Ho latela hore na o arabela joang, o kanna oa hloka ho tšeloa letsatsi le leng le le leng ho tloha matsatsing a mararo ho isa ho a supileng.

Prednisone

Orn prednisone e fumaneha ka mabitso a kang Deltasone, Intensol, Rayos le Sterapred. Meriana ena e ka sebelisoa sebakeng sa li-steroid tsa IV, haholo-holo haeba u e-na le ho khutlela morao hanyane ka hanyane.

Prednisone e boetse e sebelisetsoa ho u thusa ho theoha kamora ho amohela li-steroids tsa IV, hangata bakeng sa beke e le 'ngoe kapa tse peli. Mohlala, o ka nka li-milligram tse 60 ka letsatsi matsatsi a mane, limiligrama tse 40 ka letsatsi matsatsi a mane, ebe limiligrama tse 20 ka letsatsi matsatsi a mane.


Decadron

Decadron ke lebitso la lebitso la dexamethasone ea molomo. Ho nka tekanyetso ea letsatsi le letsatsi ea li-milligrams tse 30 (mg) beke e bontšitsoe hore e sebetsa hantle ho phekoleng ho khutla ha MS.

Sena se ka lateloa ke 4-6 mg letsatsi le leng le le leng nako e telele joalo ka khoeli. Ngaka ea hau e tla u bontša tekanyetso e nepahetseng ea ho qala.

Na ea sebetsa?

Ho bohlokoa ho hlokomela hore li-corticosteroids ha lia lebelloa ho fana ka melemo ea nako e telele kapa ho fetola tsela ea MS.

Ho na le bopaki ba hore li ka u thusa ho hlaphoheloa ha u khutlela mokhoeng ka potlako. Ho ka nka matsatsi a 'maloa ho utloa matšoao a hau a MS a ntlafala.

Empa feela joalokaha MS e fapana haholo ho tloha ho motho e mong ho ea ho e mong, ho joalo le ka kalafo ea steroid. Ha ho khonehe ho bolela esale pele hore na e tla u thusa hore u fole joang kapa hore na e tla nka nako e kae.

Liphuputso tse 'maloa tse nyane li bontšitse hore litekanyetso tse tšoanang tsa molomo oa corticosteroids li ka sebelisoa sebakeng sa lethal dose IV methylprednisolone.

A 2017 e phethile ka hore methylprednisolone ea molomo ha e tlase ho IV methylprednisolone, 'me le tsona li mamellane hantle ebile li bolokehile.

Kaha li-steroids tsa molomo li bonolo ebile ha li theko e tlase, e kanna ea ba mokhoa o motle oa kalafo ea IV, haholo haeba ts'oaetso e le bothata ho uena.

Botsa ngaka ea hau hore na li-steroids tsa molomo ke khetho e ntle ho uena.

Tšebeliso ea steroid bakeng sa litla-morao tsa MS

Tšebeliso ea lithethefatsi tse phahameng tsa "corticosteroids" hangata e mamelloa hantle. Empa li na le litla-morao. Tse ling u tla li utloa hang-hang. Tse ling e ka ba litholoana tsa kalafo e phetoang kapa ea nako e telele.

Liphello tsa nakoana

Ha u ntse u nka li-steroid, u ka ba le khatello ea nakoana ea matla e ka u thatafalletsang ho robala kapa hona ho lula u khutsitse u phomole. Li ka baka le maikutlo le boits'oaro. U ka 'na ua ikutloa u e-na le tšepo e feteletseng kapa u potlakile ha u le li-steroids.

Hammoho, litla-morao tsena li ka etsa hore o batle ho sebetsana le merero e meholo kapa ho jara boikarabello bo bongata ho feta kamoo o lokelang.

Matšoao ana hangata ke a nakoana mme a qala ho ntlafala ha o ntse o fokotsa meriana.

Litla-morao tse ling tse ka bang teng li kenyelletsa:

  • makhopho
  • ho tsubisa sefahleho
  • ho itšoara hampe
  • ho tepella maikutlo
  • ho ruruha ha matsoho le maoto (ho tsoa polokelong ea metsi le sodium)
  • hlooho e opang
  • takatso e matla ea lijo
  • ho eketsa tsoekere ea mali
  • khatello ea mali e eketsehileng
  • ho hlobaela
  • theola ho hanyetsa tšoaetso
  • Tatso ea tšepe molomong
  • bofokoli ba mesifa
  • ho koata mala kapa liso

Liphello tsa nako e telele

Kalafo ea steroid ea nako e telele e ka lebisa ho litla-morao tse ling tse kang:

  • lera la mahlo
  • glaucoma e ntseng e mpefala
  • lefu la tsoekere
  • lefu la ho fokola ha masapo
  • boima ba 'mele

Ho thella

Ho bohlokoa ho latela ka hloko litaelo tsa ngaka ea hau mabapi le ho tlosa li-steroid. Haeba u khaotsa ho li nka ka tšohanyetso, kapa haeba u theoha kapele haholo, u ka ba le matšoao a ho khaotsa.

Prednisone e ka ama tlhahiso ea hau ea cortisol, haholo haeba o e nka nako e fetang libeke tse 'maloa ka nako. Matšoao a hore o tima kapele haholo a ka kenyelletsa:

  • bohloko ba mmele
  • bohloko ba manonyeletso
  • mokgathala
  • hlooho e bobebe
  • ho nyekeloa ke pelo
  • ho felloa ke takatso ya dijo
  • bofokoli

Ho emisa Decadron ka tšohanyetso ho ka lebisa ho:

  • pherekano
  • Ho otsela
  • hlooho e opang
  • ho felloa ke takatso ya dijo
  • boima ba 'mele
  • bohloko ba mesifa le manonyeletso
  • ho ebola letlalo
  • ho koata mala le ho hlatsa

Tsa Tsau-tsau

Corticosteroids e sebelisoa ho phekola matšoao a matla le ho khutsufatsa bolelele ba ho khutla ha MS. Ha li phekole lefu ka bolona.

Ntle le haeba ho na le pono ea tahlehelo, kalafo ea MS e khutlela morao ha e potlake. Empa e lokela ho qalisoa kapele kamoo ho ka khonehang.

Liqeto mabapi le melemo le litla-morao tsa meriana ena li tlameha ho etsoa ka bonngoe. Lintho tseo u ka li tšohlang le ngaka li kenyelletsa:

  • ho tiea ha matšoao a hau le hore na ho khutlela morao ho ama bokhoni ba hau ba ho phetha mesebetsi ea hau ea letsatsi le letsatsi joang
  • mofuta o mong le o mong oa steroid o tsamaisoa joang le hore na o khona ho latela melaoana eo
  • litla-morao tse ka bang teng le hore na li ka ama bokhoni ba hau ba ho sebetsa joang
  • mathata afe kapa afe a ka bang teng, ho kenyeletsoa hore na li-steroid li ka ama maemo a hau a mang a kang lefu la tsoekere kapa mathata a bophelo bo botle ba kelello
  • litšebelisano life kapa life tse ka bang teng le meriana e meng
  • ke liphekolo life tsa steroid tse koaeloang ke inshorense ea hau ea bongaka
  • ke mekhoa efe ea kalafo e fumanehang bakeng sa matšoao a itseng a ho khutlela mokhoeng oa hau hape

Ke mohopolo o motle ho ba le puisano ena nakong e tlang ha u etela ngaka ea methapo. Ka tsela eo, o tla be o itokiselitse ho nka qeto ha o ka oela hape.

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