Teko ea Pyruvate Kinase

Litaba

• Hobaneng ha Teko ea Pyruvate Kinase e Laeloa?
• Teko e Laoloa Joang?
• Likotsi Tsa Teko ke Life?
• Ho utloisisa litholoana tsa hau

Teko ea Pyruvate Kinase

Lisele tse khubelu tsa mali (RBCs) li tsamaisa oksijene 'meleng oohle oa hau. Enzyme e tsejoang e le pyruvate kinase ea hlokahala 'meleng oa hau ho etsa li-RBC le ho sebetsa hantle. Pyruvate kinase testis ke teko ea mali e sebelisetsoang ho lekanya maemo a pyruvate kinase 'meleng oa hau.

Ha o na le pyruvate kinase e nyane haholo, li-RBC tsa hau li senyeha kapele ho feta tloaelo. Sena se fokotsa palo ea li-RBC tse fumanehang ho isa oksijene lithong tsa bohlokoa, lisele le lisele. Boemo bo hlahisoang ke "hemolytic anemia" bo ka ba le litlamorao tse kholo bophelong.

Matšoao a phokolo ea mali ea hemolytic a kenyelletsa:

• jaundice (bosehla ba letlalo)
• ho holisa spleen (mosebetsi oa mantlha oa spleen ke ho sefa mali le ho senya li-RBC tsa khale le tse senyehileng)
• khaello ea mali (khaello ea li-RBC tse phetseng hantle)
• letlalo le putswa
• mokgathala

Ngaka ea hau e ka tseba hore na u na le khaello ea pyruvate kinase ho latela litholoana tsa liteko tsena le tse ling tsa tlhahlobo.

Hobaneng ha Teko ea Pyruvate Kinase e Laeloa?

Ho haella ha Pyruvate kinase ke lefu la liphatsa tsa lefutso le feteletseng. Sena se bolela hore motsoali e mong le e mong o na le lefutso le nang le sekoli bakeng sa lefu lena. Le ha liphatsa tsa lefutso li sa hlahisoe ke e mong oa batsoali (ho bolelang hore ha ho na khaello ea pyruvate kinase), tšobotsi e fetelletseng e na le monyetla oa 1-in-4 oa ho hlaha ho bana ba bang bao batsoali ba nang le bona hammoho.

Bana ba tsoetsoeng ke batsoali ba nang le lefutso la "pyruvate kinase" ba tla lekoa bakeng sa lefu lena ba sebelisa teko ea pyruvate kinase. Ngaka ea hau e kanna ea laela tlhahlobo ha u bona matšoao a khaello ea pyruvate kinase. Lintlha tse bokelletsoeng tlhahlobong ea 'mele, tlhahlobo ea pyruvate kinase, le liteko tse ling tsa mali li tla thusa ho netefatsa tlhahlobo.

Teko e Laoloa Joang?

Ha ho hlokahale hore u etse letho le ikhethang ho itokisetsa tlhahlobo ea pyruvate kinase. Leha ho le joalo, hangata tlhahlobo e fuoa bana ba banyenyane, ka hona batsoali ba ka batla ho bua le bana ba bona ka hore na tlhahlobo e tla ikutloa joang. O ka bonts'a tlhahlobo ka popi ho thusa ho fokotsa matšoenyeho a ngoana oa hau.

Teko ea pyruvate kinase e etsoa ka mali a nkiloeng nakong e tloaelehileng ea ho hula mali. Mofani oa tlhokomelo ea bophelo o tla nka sampole ea mali letsohong la hao kapa letsohong a sebelisa nale e nyane kapa lehare le bitsoang lancet.

Mali a tla bokella ka har'a tube ebe a ea labong ho ea hlahlojoa. Ngaka ea hau e tla khona ho u fa leseli mabapi le liphetho le hore na li bolelang.

Likotsi Tsa Teko ke Life?

Bakuli ba etsa tlhahlobo ea pyruvate kinase ba ka ba le ho se phutholohe nakong ea ha mali a ntse a huloa. Ho kanna ha ba le bohloko setšeng sa ente ho tsoa litsing tsa nale. Kamora moo, bakuli ba ka utloa bohloko, ho longoa kapa ho opeloa setsing sa ente.

Likotsi tsa tlhahlobo li nyane. Likotsi tse ka bang teng tsa ho hula mali ho kenyelletsa:

• ho thatafalloa ho fumana sampole, ho hlahisang lithupa tse ngata tsa nale
• ho tsoa mali a mangata sebakeng sa nale
• ho akheha ka lebaka la tahlehelo ea mali
• pokello ya madi tlasa letlalo, a tsejwang ka hore ke hematoma
• nts'etsopele ea tšoaetso moo letlalo le robehileng ke nale

Ho utloisisa litholoana tsa hau

Liphetho tsa tlhahlobo ea pyruvate kinase li tla fapana ho latela laboratori e hlahlobang sampole ea mali. Boleng bo tloaelehileng bakeng sa teko ea pyruvate kinase hangata ke 179 hammoho kapa ho tlosa li-unit tse 16 tsa pyruvate kinase ho li-milliliters tse 100 tsa li-RBC. Maemo a tlase a pyruvate kinase a supa boteng ba khaello ea pyruvate kinase.

Ha ho na pheko bakeng sa khaello ea pyruvate kinase. Haeba u fumanoa u e-na le boemo bona, ngaka ea hau e kanna ea khothaletsa kalafo tse fapaneng. Maemong a mangata, bakuli ba nang le khaello ea pyruvate kinase ba tla hloka ho tšeloa mali ho nkela li-RBC tse senyehileng. Tšelo ea mali ke ente ea mali e tsoang ho mofani.

Haeba matšoao a lefu lena a le matla haholo, ngaka ea hau e kanna ea khothaletsa splenectomy (ho tlosoa hoa spleen). Ho tlosa spleen ho ka thusa ho fokotsa palo ea li-RBC tse senngoang. Le ha spleen e tlositsoe, matšoao a lefu lena a ka sala. Litaba tse monate ke hore kalafo e kanna ea fokotsa matšoao a hau le ho ntlafatsa bophelo ba hau.