Lethathamo la Meriana ea Rheumatoid Arthritis

Litaba

• DMARD le biologics
• Janus amanang kinase inhibitors
• Acetaminophen
• Lithethefatsi tse seng khahlanong le ho ruruha (li-NSAID)
• Ibuprofen (Advil, Motrin IB, Nuprin)
• Sodium ea Naproxen (Aleve)
• Aspirin (Bayer, Bufferin, Mohalaleli Joseph)
• Li-NSAID tsa ngaka
• Diclofenac / misoprostol (Arthrotec)
• Capsaicin ea lihlooho tsa sehlooho (Capsin, Zostrix, Dolorac)
• Diclofenac gel ea lihlooho tsa lihlooho tsa sodium (Voltaren 1%)
• Tharollo ea lihlooho tsa sodium ea Diclofenac (Pennsaid 2%)
• Lithethefatsi tse bohloko tsa opioid
• Corticosteroids
• Li-immunosuppressants
• Tsa Tsau-tsau

Kakaretso

Ramatiki ea ramatiki (RA) ke mofuta oa bobeli o atileng haholo oa ramatiki, o amang Maamerika a ka bang limilione tse 1.5. Ke lefu la ho ruruha le bakoang ke ho itšireletsa mafung. Lefu lena le hlaha ha 'mele oa hau o hlasela lisele tsa ona tse phetseng hantle tse kopanetsoeng. Sena se fella ka bofubelu, ho ruruha le bohloko.

Morero oa mantlha oa lithethefatsi tsa RA ke ho thibela ho ruruha. Sena se thusa ho thibela tšenyo e kopanetsoeng. Bala pele ho ithuta ka likhetho tse ngata tsa kalafo bakeng sa RA.

DMARD le biologics

Lithethefatsi tse fetolang mafu li-antirheumatic (DMARDs) li sebelisoa ho fokotsa ho ruruha. Ho fapana le meriana e meng e fokotsang bohloko le ho ruruha ka nakoana, li-DMARD li ka liehisa kholo ea RA. Sena se bolela hore o kanna oa ba le matšoao a fokolang mme oa senyeha hanyane ka nako.

Li-DMARD tse tloaelehileng ho sebelisoa ho phekola RA li kenyelletsa:

• hydroxychloroquine (Plaquenil)
• leflunomide (Arava)
• methotrexate (Trexall)
• sulfasalazine (Azulfidine)
• minocycline (Minocin)

Biologics ke lithethefatsi tse ka kenang. Ba sebetsa ka ho thibela litsela tse itseng tsa ho ruruha tse entsoeng ke lisele tsa 'mele tsa ho itšireletsa mafung. Sena se fokotsa ho ruruha ho bakoang ke RA. Lingaka li fana ka biologics ha li-DMARD feela li sa lekana ho phekola matšoao a RA. Likokoana-hloko ha li khothalletsoe bakeng sa batho ba nang le ts'ireletso ea 'mele ea tšoaetso kapa tšoaetso. Lebaka ke hore ba ka phahamisa kotsi ea tšoaetso e tebileng.

Li-biologics tse tloaelehileng haholo li kenyelletsa:

• abatacept (Orencia)
• Rituximab (Rituxan)
• tocilizumab (Actemra)
• anakinra (Kineret)
• adalimumab (Humira)
• etanercept (Enbrel)
• infliximab (Khopotso)
• pegol ea setifikeiti (Cimzia)
• golimumab (Simponi)

Janus amanang kinase inhibitors

Ngaka ea hau e ka fana ka litlhare tsena haeba li-DMARD kapa biologics li sa u sebetse. Meriana ena e ama liphatsa tsa lefutso le tšebetso ea lisele tsa 'mele tse itšireletsang mafung. Li thusa ho thibela ho ruruha le ho emisa tšenyo ea manonyeletso le lisele.

Janus associated kinase inhibitors a kenyelletsa:

• Tofacitinib (Xeljanz, Xeljanz XR)
• baricitinib

Baricitinib ke moriana o mocha o ntseng o lekoa. Boithuto bo bontša hore e sebeletsa batho ba sa atleheng ka li-DMARD.

Litla-morao tse tloaelehileng tsa lithethefatsi tsena li kenyelletsa:

• hlooho e opang
• mafu a holimo a ho hema, joalo ka tšoaetso ea sinus kapa sefuba se tloaelehileng
• ho petetsana nko
• nko e tsoang
• metso o bohloko
• letšollo

Acetaminophen

Acetaminophen e fumaneha khaontareng (OTC) ntle le lengolo la ngaka le tsoang ho ngaka ea hau. E hlaha e le sethethefatsi sa molomo le phepelo ea 'mala. Lithethefatsi tse ling li sebetsa haholo ho fokotsa ho ruruha le ho phekola bohloko ho RA. Lebaka ke hore acetaminophen e ka phekola bohloko bo bobebe ho isa ho bo itekanetseng, empa ha e na tšebetso e khahlano le ho ruruha. Sena se bolela hore ha e sebetse hantle ho phekola RA.

Moriana ona o na le kotsi ea mathata a tebileng a sebete, ho kenyeletsoa le ho hloleha ha sebete. U lokela ho noa moriana o le mong feela o nang le acetaminophen ka nako.

Lithethefatsi tse seng khahlanong le ho ruruha (li-NSAID)

Li-NSAID ke tse ling tsa lithethefatsi tse sebelisoang haholo tsa RA. Ho fapana le mefuta e meng ea ho kokobetsa bohloko, li-NSAID li bonahala li sebetsa haholo ho phekoleng matšoao a RA. Lebaka ke hobane li thibela ho ruruha.

Batho ba bang ba sebelisa li-NSAID tsa OTC. Leha ho le joalo, li-NSAID tse matla li fumaneha ka lengolo la ngaka.

Litla-morao tsa li-NSAID li kenyelletsa:

• ho koata mala
• liso
• khoholeho ea mobu kapa ho chesa lesoba mpeng kapa mala
• ho tsoa mali ka mpeng
• tšenyo ea liphio

Maemong a sa tloaelehang, litla-morao tsena li ka bolaea (tsa baka lefu). Haeba u sebelisa li-NSAID nako e telele, ngaka ea hau e tla hlokomela tšebetso ea liphio tsa hau. Sena se ka etsahala haholoholo haeba o se o ntse o na le lefu la liphio.

Ibuprofen (Advil, Motrin IB, Nuprin)

OTC ibuprofen ke NSAID e tloaelehileng ka ho fetisisa. Ntle le haeba u laetsoe ke ngaka, ha ua lokela ho sebelisa ibuprofen ka matsatsi a fetang a 'maloa ka nako. Ho noa moriana ona nako e telele ho ka baka ho tsoa mali ka mpeng. Kotsi ena e kholo ho batho ba baholo.

Ibuprofen le eona e fumaneha ka matla a ngaka. Liphetolelong tsa ngaka, litekanyetso li phahame. Ibuprofen e ka boela ea kopanngoa le mofuta o mong oa lithethefatsi tse bohloko tse bitsoang opioids. Mehlala ea meriana ena ea ngaka e kenyelletsa:

• ibuprofen / hydrocodone (Vicoprofen)
• ibuprofen / oxycodone (Combunox)

Sodium ea Naproxen (Aleve)

Naproxen sodium ke OTC NSAID. Hangata e sebelisoa e le mokhoa o fapaneng le ibuprofen. Lebaka ke hore e baka litla-morao tse fokolang. Mefuta e fanoeng ke ngaka ea sethethefatsi sena e fana ka litekanyo tse matla.

Aspirin (Bayer, Bufferin, Mohalaleli Joseph)

Aspirin ke moriana o kokobetsang bohloko oa molomo. E sebelisetsoa ho phekola bohloko bo fokolang, feberu le ho ruruha. E ka sebelisoa ho thibela lefu la pelo le stroke.

Li-NSAID tsa ngaka

Ha li-OSA NSAID li sa tlose matšoao a hau a RA, ngaka ea hau e kanna ea u fa lengolo la ngaka la NSAID. Tsena ke lithethefatsi tsa molomo. Likhetho tse tloaelehileng haholo li kenyelletsa:

• mahlatse (mahlatse)
• ibuprofen (lengolo la ngaka-matla)
• Nthabeleng (Relafen)
• naproxen sodium (Anaprox)
• naproxen (Naprosyn)
• piroxicam (Feldene)

Li-NSAID tse ling li kenyelletsa:

• diclofenac (Voltaren, Diclofenac Sodium XR, Cataflam, Cambia)
• diflunisal
• indomethacin (Indocin)
• ketoprofen (Orudis, Ketoprofen ER, Oruvail, Actron)
• etodolac (Lodine)
• fenoprofen (Nalfon)
• obolela
• ketorolac (Toradol)
• meclone
• mefenamic acid (Ponstel)
• meloxicam (Mobic)
• oxaprozin (Letsatsi la letsatsi)
• sulindac (Kliniki)
• salsalate (Disalcid, Amigesic, Marthritic, Salflex, Mono-Gesic, Anaflex, Salsitab)
• tolmetin (Tolectin)

Diclofenac / misoprostol (Arthrotec)

Diclofenac / misoprostol (Arthrotec) ke sethethefatsi sa molomo se kopanyang NSAID diclofenac le misoprostol. Li-NSAID li ka baka lisosa tsa mala. Meriana ena e thusa ho ba thibela.

Capsaicin ea lihlooho tsa sehlooho (Capsin, Zostrix, Dolorac)

Capsaicin topical OTC cream e ka kokobetsa bohloko bo bohloko bo bakoang ke RA. U tlotsa tranelate ena libakeng tse bohloko 'meleng oa hau.

Diclofenac gel ea lihlooho tsa lihlooho tsa sodium (Voltaren 1%)

Voltaren gel 1% ke NSAID bakeng sa ts'ebeliso ea lihlooho. Sena se bolela hore ua e tšela letlalong la hao. E lumelloa ho phekola bohloko bo kopantsoeng, ho kenyelletsa matsohong le mangoleng.

Meriana ena e baka litla-morao tse tšoanang ho li-NSAID tsa molomo. Leha ho le joalo, ke liperesente tse 'ne feela tsa sethethefatsi sena se kenang' meleng oa hau. Sena se bolela hore o kanna oa ba le litla-morao tse fokolang.

Tharollo ea lihlooho tsa sodium ea Diclofenac (Pennsaid 2%)

Diclofenac sodium (Pennsaid 2%) ke tharollo ea lihlooho tse sebelisetsoang bohloko ba mangole. U e tšela mangoleng ho kokobetsa bohloko.

Lithethefatsi tse bohloko tsa opioid

Li-opioids ke lithethefatsi tse bohloko ka ho fetisisa 'marakeng. Li fumaneha feela joalo ka litlhare tsa ngaka. Li hlaha ka mefuta ea molomo le e nang le kente. Li-opioid li sebelisoa feela kalafong ea RA bakeng sa batho ba nang le RA e matla ba bohlokong bo boholo. Meriana ena e ka ba mokhoa oa ho itloaetsa. Haeba ngaka ea hau eu fa sethethefatsi sa opioid, ba tla u shebella haufi-ufi.

Corticosteroids

Corticosteroids e boetse e bitsoa steroids. Li tla joaloka lithethefatsi tsa molomo le tse entsoang. Lithethefatsi tsena li ka thusa ho fokotsa ho ruruha ho RA. Li ka thusa ho fokotsa bohloko le tšenyo e bakiloeng ke ho ruruha. Meriana ena ha e khothaletsoe bakeng sa ts'ebeliso ea nako e telele.

Litla-morao li ka kenyelletsa:

• tsoekere e phahameng maling
• diso tsa ka maleng
• khatello e phahameng ea mali
• litlamorao tsa maikutlo, joalo ka ho teneha le ho hlonama
• lera la leihlo le ka leihlong la hao
• lefu la ho fokola ha masapo

Li-steroid tse sebelisetsoang RA li kenyelletsa:

• betamethasone
• prednisone (Deltasone, Sterapred, Metsi Pred)
• dexamethasone (Dexpak Taperpak, Decadron, Hexadrol)
• cortisone
• hydrocortisone (Cortef, A-Hydrocort)
• methylprednisolone (Medrol, Methacort, Depopred, Predacorten)
• sebeletso

Li-immunosuppressants

Lithethefatsi tsena li loantša tšenyo e bakiloeng ke mafu a itšireletsang mafung a kang RA. Leha ho le joalo, lithethefatsi tsena li ka u etsa hore u tloaetse ho kula le tšoaetso haholoanyane. Haeba ngaka ea hau eu fa e 'ngoe ea lithethefatsi tsena, li tla u shebella ka hloko nakong ea kalafo.

Lithethefatsi tsena li hlaha ka mefuta ea molomo le e nang le kente. Li kenyeletsa:

• cyclophosphamide (Cytoxan)
• cyclosporine (Gengraf, Neoral, Sandimmune)
• azathioprine (Azasan, Imuran)
• hydroxychloroquine (Plaquenil)

Tsa Tsau-tsau

Sebetsa le ngaka ea hau ho fumana kalafo ea RA e u sebeletsang hantle. Ka likhetho tse ngata tse fumanehang, uena le ngaka ea hau le kanna la fumana e tla bebofatsang matšoao a hau a RA le ho ntlafatsa bophelo ba hau.