Teko ea mali ea Calcitonin
Teko ea mali ea calcitonin e lekanya boemo ba hormone calcitonin maling.
Ho hlokahala sampole ea mali.
Hangata ha ho na litokisetso tse khethehileng tse hlokahalang.
Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ikutloa feela ho hlaba kapa ho hlaba. Kamora moo, ho kanna ha ba le ho longoa kapa ho longoa hanyenyane. Haufinyane sena sea fela.
Calcitonin ke hormone e hlahisoang liseleng tsa C tsa qoqotho. Tšoelesa ea qoqotho e kahare ho molala oa hau o ka tlase. Calcitonin e thusa ho laola ho senyeha le ho aha lesapo hape.
Lebaka le tloaelehileng la ho etsa tlhahlobo ke hore na u kile ua etsoa opereishene ho tlosa hlahala ea qoqotho e bitsoang mofets'e oa medullary. Teko e lumella mofani oa hao oa tlhokomelo ea bophelo ho lekola hore na hlahala e namme (metastasized) kapa e khutlile (hlahala e iphetang).
Mofani oa hau a ka boela a laela tlhahlobo ea calcitonin ha u e-na le matšoao a mofetše oa kankere ea qoqotho kapa lefu la endocrine neoplasia (MEN), kapa nalane ea lelapa ea maemo ana. Calcitonin e kanna ea ba e phahame haholo lihlahala tse ling tse kang:
- Insulinoma (hlahala ka har'a manyeme e hlahisang insulin e ngata haholo)
- Kankere ea matšoafo
- VIPoma (mofets'e o atisang ho hola ho tsoa lisele tsa sehlekehlekeng)
Boleng bo tloaelehileng bo ka tlase ho 10 pg / mL.
Basali le banna ba ka ba le litekanyetso tse fapaneng tse tloaelehileng, banna ba na le litekanyetso tse phahameng.
Ka linako tse ling, calcitonin e maling e hlahlojoa makhetlo a 'maloa kamora hore u fuoe sethunya (ente) ea moriana o khethehileng o hlohlelletsang tlhahiso ea calcitonin.
U tla hloka teko ena e eketsehileng haeba motheo oa hau oa calcitonin o tloaelehile, empa mofani oa hau o belaela hore o na le mofetše oa kankere ea qoqotho.
Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li ka leka mefuta e fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.
Boemo bo phahameng ho feta bo tloaelehileng bo ka supa:
- Insulinoma
- Kankere ea matšoafo
- Kankere ea medullary ea thyroid (e tloaelehileng haholo)
- VIPoma
Methati e phahameng ho feta e tloaelehileng ea calcitonin e ka hlaha ho batho ba nang le lefu la liphio, ba tsubang le boima ba 'mele bo phahameng. Hape, ea eketseha ha u noa meriana e meng ho emisa tlhahiso ea asiti ea mala.
Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho nka mali ho batho ba bang ho ka ba thata ho feta ho ba bang.
Likotsi tse ling tse amanang le ho huloa mali li nyane, empa li ka kenyelletsa:
- Ho tsoa mali a mangata
- Ho akheha kapa ho ikutloa o le hlooho e boima
- Li-punctures tse ngata ho fumana methapo
- Hematoma (mali a bokellanang ka tlasa letlalo)
- Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)
Serum calcitonin
Tlisahurhur FR, Demay MB, Kronenberg HM. Li-hormone le mathata a metabolism ea diminerale. Ka: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, bahlophisi. Buka ea Williams ea Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: khaolo ea 28.
CC ea Chernecky, Berger BJ. Calcitonin (thyrocalcitonin) - serum. Ka: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. St Louis, MO: Elsevier Saunders; 2013: 276-277.
Findlay DM, Tonakholo ea Sexton, Martin TJ. Calcitonin. Ka: Jameson JL, De Groot LJ, oa Kretser DM, et al, eds. Endocrinology: Batho ba baholo le bana. La 7th. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 58.