Teko ea mali ea Parathyroid hormone (PTH)

Teko ea PTH e lekanya boemo ba hormone ea parathyroid maling.

PTH e emela hormone ea parathyroid. Ke hormone ea protheine e ntšitsoeng ke tšoelesa ea parathyroid.

Teko ea laboratori e ka etsoa ho lekanya palo ea PTH maling a hau.

Ho hlokahala sampole ea mali.

Botsa mofani oa tlhokomelo ea bophelo haeba u lokela ho khaotsa ho ja kapa ho noa nako e itseng pele ho tlhahlobo. Hangata, ha ho hlokahale hore u itime lijo kapa u khaotse ho noa.

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ikutloa feela ho hlaba kapa ho hlaba. Kamora moo, ho kanna ha ba le ho longoa kapa ho longoa hanyenyane. Haufinyane sena sea fela.

PTH e lokolloa ke litšoelesa tsa parathyroid. Li-gland tse 4 tse nyane tsa parathyroid li molaleng, haufi kapa li hokahane le lehlakoreng le ka morao la tšoelesa ea qoqotho. Tšoelesa ea qoqotho e molaleng, ka holimo feela moo masapo a molala oa hau a kopanang teng bohareng.

PTH e laola maemo a calcium, phosphorus le vithamine D maling. Ho bohlokoa ho laola kholo ea masapo. Mofani oa hau a ka laela tlhahlobo ena haeba:

• O na le boemo bo phahameng ba calcium kapa phosphorus e tlase mading a hao.
• U na le lefu la ho fokola ha masapo le matla hoo ho ke keng ha hlalosoa kapa ha le arabele kalafo.
• U na le lefu la liphio.

Ho thusa ho utloisisa hore na PTH ea hau e tloaelehile, mofani oa hau o tla lekanya calcium ea mali ka nako e le ngoe.

Litekanyetso tse tloaelehileng ke li-picograms tse 10 ho isa ho tse 55 ka mililitara (pg / mL).

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li leka liteko tse fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.

Boleng ba PTH boemong bo tloaelehileng bo ntse bo ka ba bo sa lokelang ha maemo a calcium ea serum a phahame. Bua le mofani oa hau ka hore na sephetho sa hau se bolelang.

Boemo bo phahameng ho feta bo tloaelehileng bo ka etsahala ka:

• Mathata a eketsang phosphate kapa phosphorus maling, joalo ka lefu la liphio la nako e telele (le sa foleng)
• Ho hloleha ha mmele ho araba PTH (pseudohypoparathyroidism)
• Ho hloka calcium, e ka bang ka lebaka la ho se je calcium e lekaneng, ho se monye calcium ka maleng, kapa ho lahleheloa ke calcium e ngata haholo morong oa hau
• Bokhachane kapa ho anyesa (ho sa tloaelehang)
• Ho ruruha litšoelesa tsa parathyroid, tse bitsoang hyperparathyroidism ea mantlha
• Hlahala ea tšoelesa ea parathyroid, e bitsoang adenomas
• Mathata a vithamine D, ho kenyelletsa le letsatsi le sa lekaneng ho batho ba baholo le mathata a ho monya, ho senya le ho sebelisa vithamine D 'meleng

Boemo bo tlase ho feta bo tloaelehileng bo ka etsahala ka:

• Ho tlosoa ka phoso ha litšoelesa tsa parathyroid nakong ea ts'ebetso ea qoqotho
• Autoimmune timetso ea tšoelesa parathyroid
• Kankere e qalang karolong e ngoe ea 'mele (joalo ka sefuba, matšoafo kapa kolone) ebe e namela masapong
• K'halsiamo e fetelletseng ka nako e telele hangata e tsoa ho li-supplement tse ngata tsa calcium kapa li-antacids tse ling, tse nang le calcium carbonate kapa sodium bicarbonate (baking soda)
• Litšoelesa tsa Parathyroid ha li hlahise PTH e lekaneng (hypoparathyroidism)
• Maemo a tlase a magnesium maling
• Mahlaseli ho litšoelesa tsa parathyroid
• Sarcoidosis le lefuba
• Ho noa vithamine D e feteletseng

Maemo a mang ao tlhahlobo e ka laeloang bakeng sa ona a kenyelletsa:

• Multiple endocrine neoplasia (MEN) I
• Multiple endocrine neoplasia (MEN) II

Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho nka mali ho batho ba bang ho ka ba thata ho feta ho ba bang.

Likotsi tse ling tse amanang le ho huloa mali li nyane, empa li ka kenyelletsa:

• Ho tsoa mali a mangata
• Li-punctures tse ngata ho fumana methapo
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Hematoma (mali a bokellanang ka tlasa letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Parathormone; Parathormone (PTH) molek'hule e sa sisinyeheng; PTH e tiileng; Hyperparathyroidism - Teko ea mali ea PTH; Hypoparathyroidism - Teko ea mali ea PTH

Tlisahurhur FR, Demay MB, Kronenberg HM. Li-hormone le mathata a metabolism ea diminerale. Ka: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, bahlophisi. Buka ea Williams ea Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: khaolo ea 28.

Klemm KM, Klein MJ. Likarolo tsa biochemical tsa metabolism ea masapo. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. Philadelphia, PA: Elsevier; 2017: khaolo ea 15.