Ntlha ea VIII tlhahlobo

Sesebelisoa sa VIII ke tlhahlobo ea mali ho lekanya tšebetso ea factor VIII. Ena ke e 'ngoe ea liprotheine tse' meleng tse thusang mali ho koala.

Ho hlokahala sampole ea mali.

Ha ho litokisetso tse khethehileng tse hlokahalang.

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ikutloa feela ho hlaba kapa ho hlaba. Kamora moo, ho kanna ha ba le ho longoa kapa ho longoa hanyenyane. Haufinyane sena sea fela.

Teko ena e sebelisetsoa ho fumana sesosa sa ho tsoa mali haholo (ho fokotseha hoa mali). Kapa, ​​ho ka laeloa haeba setho sa lelapa se tsejoa hore se na le haemophilia A. Teko e kanna ea etsoa ho bona hore na kalafo ea haemophilia A e sebetsa hantle hakae.

Boleng bo tloaelehileng ke 50% ho isa ho 200% ea taolo ea laboratori kapa boleng ba tšupiso.

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Labs tse ling li sebelisa litekanyo tse fapaneng kapa li kanna tsa leka mehlala e fapaneng. Bua le mofani oa tlhokomelo ea bophelo mabapi le moelelo oa sephetho sa hau sa liteko.

Ho fokotseha ha tšebetso ea VIII ho ka bakoa ke:

• Hemophilia A (lefu le tsoang mali le bakoang ke khaello ea mali a koalang mali VIII)
• Ho hloka taolo moo liprotheine tse laolang ho hoama ha mali li fetelang ho ts'oaetso e matla ea methapo ea methapo (DIC)
• Boteng ba Factor VIII inhibitor (antibody)
• Lefu la Von Willebrand (mofuta o mong oa lefu la ho tsoa mali)

Ketsahalo e eketsehileng e ka bakoa ke:

• Botsofali
• Lefu la tsoekere
• Lefu la sebete
• Ho ruruha
• Boimana
• Botenya

Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong, le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho fumana sampole ea mali ho batho ba bang ho ka ba thata ho feta ho ba bang.

Likotsi tse ling tse amanang le ho huloa mali li nyane, empa li ka kenyelletsa:

• Ho tsoa mali a mangata
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Li-punctures tse ngata ho fumana methapo
• Hematoma (mali a bokellanang ka tlasa letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Hangata tlhahlobo ena e etsoa ho batho ba nang le mathata a ho tsoa mali. Kotsi ea ho tsoa mali a mangata e kholo ho batho ba nang le mathata a ho tsoa mali ho feta ba bang.

Lero la mali la Plasma VIII; Lebaka la antihemophilia; AHF

Carcao M, Moorehead P, Lillicrap D.Hemophilia A le B. Ho: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Melao-motheo le Tloaelo ea Motheo. La 7th. Philadelphia, PA: Elsevier; 2018: khaolo ea 135.

CC ea Chernecky, Berger BJ. Ntlha ea VIII (antihemophilia factor, AHF) - mali. Ka: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. St Louis, MO: Elsevier Saunders; 2013: 504-505.

Napolitano M, Schmaier AH, Kessler CM. Coagulation le fibrinolysis. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 39.