Teko ea protheine ea Bence-Jones ea boleng

Teko ena e lekanya boemo ba liprotheine tse sa tloaelehang tse bitsoang liprotheine tsa Bence-Jones morotong.

Mohlala oa moroto o hloekileng o hlokahale. Mokhoa oa ho tšoasa o hloekileng o sebelisetsoa ho thibela likokoana-hloko tse tsoang botoneng kapa botšehaling hore li se ke tsa kena sampoleng ea moroto. Ho bokella moroto oa hau, mofani oa tlhokomelo ea bophelo a ka u fa sesebelisoa se khethehileng sa ho ts'oasa se hloekileng se nang le tharollo ea ho hloekisa le ho hlakola ha nyopa. Latela litaelo hantle hore liphetho li nepahale.

Mohlala o romelloa labong. Ha ba le moo, e 'ngoe ea mekhoa e mengata e sebelisoa ho fumana liprotheine tsa Bence-Jones. Mokgwa o mong o bitswang immunoelectrophoresis, ke o nepahetseng ka ho fetesisa.

Teko e kenyelletsa feela ho rota ho tloaelehileng, 'me ha ho na bothata.

Liprotheine tsa Bence-Jones ke karolo ea lisireletsi tse tloaelehileng tse bitsoang liketane tse bobebe. Hangata liprotheine tsena ha li le morong. Ka linako tse ling, ha 'mele oa hau o etsa li-antibodies tse ngata haholo, boemo ba liketane tsa mabone le bona boa nyoloha. Liprotheine tsa Bence-Jones li nyane hoo li ka tlhotliloeng ke liphio. Liprotheine li tšela ka morong.

Mofani oa hau a ka odara tlhahlobo ena:

• Ho hlahloba maemo a lebisang ho protheine ka morong
• Haeba u na le liprotheine tse ngata morotong oa hau
• Haeba u na le matšoao a mofets'e oa mali o bitsoang multiple myeloma

Sephetho se tloaelehileng se bolela hore ha ho liprotheine tsa Bence-Jones tse fumanehang morong oa hau.

Liprotheine tsa Bence-Jones ha li fumanehe hangata morong. Haeba li teng, hangata li amahanngoa le myeloma e mengata.

Sephetho se sa tloaelehang se ka boela sa bakoa ke:

• Liprotheine tse hahiloeng ka mokhoa o sa tloaelehang lithong le lithong (amyloidosis)
• Kankere ea mali e bitsoang chronic lymphocytic leukemia
• Kankere ea Lymph system (lymphoma)
• Haha maling a protheine e bitsoang M-protein (monoclonal gammopathy ea bohlokoa bo sa tsejoeng; MGUS)
• Ho hloleha ho sa foleng ha renal

Ha ho na likotsi ka tlhahlobo ena.

Liketane tse bobebe tsa Immunoglobulin - moroto; Protheine ea Urine Bence-Jones

• Tsamaiso ea monna ea ho ntša metsi

CC ea Chernecky, Berger BJ. Liprotheine electrophoresis - moroto. Ka: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. St Louis, MO: Elsevier Saunders; 2013: 920-922.

Riley RS, McPherson RA. Tlhahlobo ea mantlha ea moroto. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 28.

Rajkumar SV, Dispenzieri A. Multiple myeloma le mathata a amanang le ona. Ka: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, bahlophisi. Abeloff's Clinical Oncology. La 6th. Philadelphia, PA: Elsevier; 2020: khaolo ea 101.