Boikaketsi

Hypogonadism e etsahala ha litšoelesa tsa 'mele tsa thobalano li hlahisa lihormone tse nyane kapa li se na letho. Ho banna, litšoelesa tsena ke li-testes. Ho basali, litšoelesa tsena ke mae a bomme.

Lebaka la hypogonadism e ka ba la mantlha (li-testes kapa mae a bomme) kapa tsa bobeli (bothata ba pituitary kapa hypothalamus). Ho hypogonadism ea mantlha, mae a bomme kapa liteko ka botsona ha li sebetse hantle. Lisosa tsa hypogonadism ea mantlha li kenyelletsa:

• Mathata a mang a autoimmune
• Mathata a liphatsa tsa lefutso le kholo
• Tšoaetso
• Lefu la sebete le liphio
• Mahlaseli a kotsi (ho gonads)
• Phekolo
• Tsietsi
  

Mathata a atileng haholo a liphatsa tsa lefutso a bakang hypogonadism ea mantlha ke Turner syndrome (ho basali) le lefu la Klinefelter (ho banna).

Haeba u se u ntse u e-na le mathata a mang a ho itšireletsa mafung u ka ba kotsing e kholo ea tšenyo ea 'mele ho li-gonads. Tsena li ka kenyelletsa mathata a amang sebete, litšoelesa tsa adrenal le litšoelesa tsa qoqotho, hammoho le mofuta oa 1 oa lefu la tsoekere.

Bohareng ba hypogonadism, litsi tsa bokong tse laolang li-gonads (hypothalamus le pituitary) ha li sebetse hantle. Lisosa tsa hypogonadism e bohareng li kenyelletsa:

• Ho ipolaisa tlala
• Ho tsoa mali sebakeng sa pituitary
• Ho noa meriana, joalo ka li-glucocorticoids le li-opiate
• Ho emisa li-anabolic steroids
• Mathata a lefutso
• Tšoaetso
• Ho haelloa ke phepo e nepahetseng
• Ho tlola tšepe (hemochromatosis)
• Mahlaseli a kotsi (ho pituitary kapa hypothalamus)
• Ka potlako, tahlehelo ea boima ba 'mele (ho kenyeletsoa le tahlehelo ea boima ba' mele kamora ho buuoa ka bariatric)
• Ho buoa (ho buuoa ka lehata haufi le pituitary)
• Tsietsi
• Lihlahala

Lebaka la lefutso la hypogonadism e bohareng ke lefu la Kallmann. Batho ba bangata ba nang le boemo bona le bona ba na le kutlo e fokotsehileng ea monko.

Ho khaotsa ho ilela khoeli ke lona lebaka le tloaelehileng la hypogonadism. Ho tloaelehile ho basali bohle mme ho etsahala ka karolelano ho ba lilemo li 50. Maemo a Testosterone a fokotseha ho banna ha ba ntse ba tsofala. Mofuta oa testosterone e tloaelehileng maling o tlase haholo ho monna ea lilemo li 50 ho isa ho 60 ho feta ho monna ea lilemo li 20 ho isa ho tse 30.

Banana ba nang le hypogonadism ba ke ke ba qala ho ea khoeling. Hypogonadism e ka ama kholo ea bona ea matsoele le bolelele. Haeba hypogonadism e hlaha kamora ho kena bonneng kapa bosaling, matšoao a basali a kenyelletsa:

• Ho chesa haholo
• Matla le maikutlo a fetoha
• Ho ilela khoeli ho fetoha ho sa tloaelehang kapa ho emisa

Ho bashanyana, hypogonadism e ama mesifa, litelu, litho tsa botona le botšehali le nts'etsopele ea lentsoe. E boetse e lebisa mathateng a kholo. Ho banna matšoao ke ana:

• Ho holisa matsoele
• Ho lahleheloa ke mesifa
• Thahasello e fokotsehileng ea thobalano (low libido)

Haeba hlahala ea pituitary kapa e 'ngoe ea boko e le teng (central hypogonadism), ho kanna ha ba le:

• Ho opeloa ke hlooho kapa ho lahleheloa ke pono
• Ho tsoa ha letsoele lebese (ho tsoa ho prolactinoma)
• Matšoao a bofokoli bo bong ba li-hormone (joalo ka hypothyroidism)

Lihlahala tse atisang ho ama pituitary ke craniopharyngioma ho bana le prolactinoma adenomas ho batho ba baholo.

U kanna ua hloka ho ba le liteko ho hlahloba:

• Boemo ba Estrogen (basali)
• Follicle e hlasimollang li-hormone (FSH level) le luteinizing hormone (LH)
• Boemo ba testosterone (banna) - tlhaloso ea teko ena ho banna le banna ba baholo ba nonneng e ka ba thata kahoo liphetho li lokela ho tšohloa le setsebi sa lihormone (endocrinologist)
• Mehato e meng ea ts'ebetso ea pituitary

Liteko tse ling li ka kenyelletsa:

• Liteko tsa mali bakeng sa phokolo ea mali le tšepe
• Liteko tsa liphatsa tsa lefutso tse kenyelletsang karyotype ho lekola sebopeho sa chromosomal
• Tekanyo ea Prolactin (hormone ea lebese)
• Palo ea peo ea botona
• Liteko tsa qoqotho

Ka linako tse ling liteko tsa ho nka litšoantšo lia hlokahala, joalo ka sonogram ea mae a bomme. Haeba ho belaelloa lefu la pituitary, ho ka etsoa MRI kapa CT scan ea boko.

U kanna ua hloka ho noa meriana e thehiloeng lihormone. Estrogen le progesterone li sebelisoa bakeng sa banana le basali. Meriana e tla ka sebopeho sa pilisi kapa sekhechana sa letlalo. Testosterone e sebelisetsoa bashanyana le banna. Moriana o ka fanoa joalo ka lesela la letlalo, letlalo la letlalo, tharollo e sebelisitsoeng mokopeng, setsiba se sebelisitsoeng ho marenene a holimo, kapa ka ente.

Bakeng sa basali ba sa kang ba tlosoa popelo, kalafo e kopaneng le estrogen le progesterone e ka fokotsa menyetla ea ho ba le mofetše oa endometrium. Basali ba nang le hypogonadism ba nang le thobalano e tlase le bona ba ka fuoa testosterone ea lethal dose kapa hormone e 'ngoe e tona e bitsoang dehydroepiandrosterone (DHEA).

Basali ba bang, liente kapa lipilisi li ka sebelisoa ho hlasimolla. Liente tsa hormone ea pituitary li ka sebelisoa ho thusa banna ho hlahisa peo. Batho ba bang ba kanna ba hloka ho buuoa le kalafo ea radiation haeba ho na le sesosa sa pituitary kapa hypothalamic sa lefu lena.

Mefuta e mengata ea hypogonadism ea phekoleha ebile e na le pono e ntle.

Basali, hypogonadism e ka baka ho hloka thari. Ho khaotsa ho ilela khoeli ke mofuta oa hypogonadism o etsahalang ka tlhaho. E ka baka mahlaseli a chesang, ho omella ka botšehaling le ho teneha habonolo ha maemo a estrogen a oa. Kotsi ea lefu la ho fokola ha masapo le lefu la pelo ea eketseha ka mor'a ho khaotsa ho ilela khoeli.

Basali ba bang ba nang le hypogonadism ba nka kalafo ea estrogen, hangata e le ba qalang ho ilela khoeli. Empa ts'ebeliso ea nako e telele ea kalafo ea lihormone e ka eketsa menyetla ea mofetše oa matsoele, maqeba a mali le lefu la pelo (haholo ho basali ba baholo). Basali ba lokela ho bua le mofani oa bona oa tlhokomelo ea bophelo ka likotsi le melemo ea kalafo ea li-hormone tsa menopausal.

Ho banna, hypogonadism e baka tahlehelo ea thobalano mme e ka baka:

• Ho hloka matla
• Ho hloka thari
• Lefu la ho fokola ha masapo
• Bofokoli

Hangata banna ba na le testosterone e tlase ha ba ntse ba tsofala. Leha ho le joalo, ho theoha ha maemo a li-hormone ha ho makatse joaloka basali.

Bua le mofani oa hau haeba u hlokomela:

• Ho tsoa ha matsoele
• Ho atolosoa ha matsoele (banna)
• Ho chesa haholo (basali)
• Ho hloka matla
• Ho lahleheloa ke moriri oa 'mele
• Ho lahleheloa ke nako ea ho ilela khoeli
• Mathata a ho ima
• Mathata ka thobalano ea hau
• Bofokoli

Banna le basali ba lokela ho letsetsa mofani oa bona haeba ba e-na le mathata a hlooho kapa a pono.

Ho boloka bophelo bo botle, boima ba 'mele bo tloaelehileng le ho ja hantle ho ka thusa maemong a mang. Lisosa tse ling li kanna tsa se thibeloe.

Ho haella ha Gonadal; Ho hloleha ha testicular; Ho hloleha ha mahe a bomme; Testosterone - hypogonadism

• Li-gonadotropin

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