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Letsatsi La Creation: 7 Phato 2021
Ntlafatsa Letsatsi: 17 November 2024
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CME 14: Current Update On Nasopharyngeal Carcinoma
Video: CME 14: Current Update On Nasopharyngeal Carcinoma

Medullary carcinoma ea qoqotho ke mofetše oa tšoelesa ea qoqotho e qalang liseleng tse hlahisang hormone e bitsoang calcitonin. Lisele tsena li bitsoa "C" lisele. Tšoelesa ea qoqotho e kahare ho molala oa hau o ka tlase.

Lebaka la medullary carcinoma ea qoqotho (MTC) ha le tsejoe. MTC e fumaneha seoelo haholo. E ka etsahala ho bana le ho batho ba baholo.

Ho fapana le mefuta e meng ea mofets'e oa qoqotho, MTC ha e na monyetla oa ho bakoa ke kalafo ea radiation molaleng e fuoeng ho alafa mofetše o mong nakong ea bongoana.

Ho na le mefuta e 'meli ea MTC:

  • Sporadic MTC, e sa sebetseng ka malapeng. Boholo ba li-MTC ha li sebetse hangata. Foromo ena e ama haholo batho ba baholo.
  • Lefa la MTC, le tsamaeang ka malapeng.

U na le kotsi e eketsehileng ea mofuta ona oa mofets'e haeba u na le:

  • Nalane ea lelapa ea MTC
  • Nalane ea lelapa ea li-endocrine neoplasia tse ngata (MEN)
  • Nalane ea pele ea pheochromocytoma, mucosal neuromas, hyperparathyroidism kapa lihlahala tsa endocrine tsa pancreatic

Mefuta e meng ea mofets'e oa qoqotho e kenyelletsa:


  • Anaplastic carcinoma ea qoqotho
  • Sefuba se latelang sa qoqotho
  • Papillary carcinoma ea qoqotho
  • Thyroid lymphoma

MTC hangata e qala joalo ka hlama e nyane mokokotlong oa qoqotho. Hape ho ka ba le ho ruruha ha lymph node molaleng. Ka lebaka leo, matšoao a ka kenyelletsa:

  • Ho ruruha ha molala
  • Ho thothofala
  • Mathata a ho hema ka lebaka la ho fokola ha lifofane
  • Khohlela
  • Khohlela le mali
  • Letšollo ka lebaka la boemo bo phahameng ba calcitonin

Mofani oa hao oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele mme a botse ka matšoao a hau le nalane ea bongaka.

Liteko tse ka sebelisoang ho fumana MTC li kenyelletsa:

  • Teko ea mali ea Calcitonin
  • Teko ea mali ea CEA
  • Ho etsa liteko tsa lefutso
  • Biopsy ea qoqotho
  • Ultrasound ea qoqotho le li-lymph node tsa molala
  • Scan ea PET

Batho ba nang le MTC ba lokela ho hlahlojoa hore na ba na le lihlahala tse ling, haholo-holo pheochromocytoma le lihlahala tsa parathyroid le lihlahala tsa parathyroid.


Kalafo e kenyelletsa ho buuoa ho tlosa tšoelesa ea qoqotho le li-lymph node tse e potileng. Hobane hona ke hlahala e sa tloaelehang, opereishene e lokela ho etsoa ke ngaka e buoang e tloaelaneng le mofuta ona oa mofets'e mme e nang le boiphihlelo ka ts'ebetso e hlokahalang.

Kalafo e eketsehileng e tla itšetleha ka litekanyetso tsa hau tsa calcitonin. Ho phahama ha maemo a calcitonin hape ho ka supa kholo e ncha ea mofetše.

  • Chemotherapy le radiation ha li sebetse hantle bakeng sa mofuta ona oa mofets'e.
  • Mahlaseli a kotsi a sebelisoa ho batho ba bang kamora ho buuoa.
  • Liphekolo tse ncha tse reretsoeng li ka fokotsa kholo ea hlahala hape. Mofani oa hau a ka u joetsa haholoanyane ka tsena, ha ho hlokahala.

Haufi le beng ka motho ba fumanoeng ba na le mefuta ea lefutso ea MTC ba kotsing e kholo ea mofets'e mme ba lokela ho buisana le bafani ba bona.

U ka fokotsa khatello ea maikutlo ea bokuli ka ho kenela sehlopha sa ts'ehetso ea mofets'e. Ho arolelana le ba bang ba nang le liphihlelo tse tšoanang le mathata ho ka u thusa hore u se ke ua ikutloa u le mong.

Batho ba bangata ba nang le MTC ba phela bonyane lilemo tse 5 kamora ho fumanoa, ho latela boemo ba mofets'e. Sekhahla sa pholoho sa lilemo tse 10 ke 65%.


Mathata a ka kenyelletsa:

  • Kankere e namela likarolong tse ling tsa 'mele
  • Litšoelesa tsa Parathyroid li tlosoa ka phoso nakong ea ts'ebetso

Bitsa mofani oa hau haeba u na le matšoao a MTC.

Thibelo e kanna ea se khonehe. Empa, ho tseba mabaka a hau a ho ipeha kotsing, haholo nalane ea lelapa la hau, ho ka u lumella ho fumana kalafo le kalafo kapele. Bakeng sa batho ba nang le nalane e matla ea malapa ea MTC, ho ka buelloa khetho ea ho tlosa tšoelesa ea qoqotho. U lokela ho buisana ka hloko ka khetho ena le ngaka e tsebang lefu lena hantle.

Qoqotho - medullary carcinoma; Kankere - thyroid (medullary carcinoma); MTC; Qoqotho nodule - medullary

  • Kankere ea qoqotho - CT scan
  • Tšoelesa ea qoqotho

Jonklass J, Cooper DS. Thyroid. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 213.

Webosaete ea National Cancer Institute. Kalafo ea mofetše oa qoqotho (motho e moholo) (PDQ) - mofuta oa litsebi tsa bophelo bo botle. www.cancer.gov/types/thyroid/hp/thyroid-tlhare-pdq. E ntlafalitsoe ka la 30 Pherekhong 2020. E fihlile ka la 6 Hlakubele 2020.

Smith PW, Hanks LR, Salomone LJ, Hanks JB. Thyroid. Ka: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Buka ea Sabiston ea Ngaka ea ho Buoa. 20th, ed. Philadelphia, PA: Elsevier Saunders; 2017: khaolo ea 36.

Viola D, Elisei R. Tsamaiso ea kankere ea qoqotho ea medullary. Kliniki ea Endocrinol Metab North Am. 2019; 48 (1): 285-301. PMID: 30717909 e fetotsoe.ncbi.nlm.nih.gov/30717909/.

Wells SA Jr, Asa SL, Dralle H. Revised American Thyroid Association litataiso bakeng sa taolo ea medullary thyroid carcinoma. Thyroid. 2015; 25 (6): 567-610. PMID: 25810047 e fetotsoe.ncbi.nlm.nih.gov/25810047/.

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