Teko ea Cholinesterase: ke eng, e etsetsoa eng le hore na sephetho se bolelang

Litaba

• E etselitsoe eng
• Litekanyetso tsa litšupiso
• Seo liphetho li se bolelang

Teko ea cholinesterase ke tlhahlobo ea laboratori e kopiloeng molemong oa ho netefatsa boemo ba ho pepesehela motho lihlahisoa tse chefo, joalo ka chefo e bolaeang likokonyana, likokoanyana, likokoana-hloko kapa manyolo, ka mohlala, li loketseng lihoai haholo, hobane li lula li kopana le lihlahisoa tsa temo.

Cholinesterase ke enzyme e teng 'meleng e ikarabellang bakeng sa ho senyeha ha ntho e bitsoang acetylcholine, neurotransmitter e ikarabellang ho laoleng tšusumetso ea methapo ea mesifa. Ho na le lihlopha tse peli tsa cholinesterase:

• Erythrocyte cholinesterase, e tsamaisoang ke lisele tse khubelu tsa mali;
• Plasma cholinesterase kapa serum, e leng cholinesterase e hlahisoang ke sebete, manyeme le mala a manyane 'me e potoloha maling a mali.

Ho lekola maemo a cholinesterase ho bohlokoa e le hore liphetoho life kapa life li ka tsebahala le ho phekoloa kapele, ho qoba mathata ho motho eo.

E etselitsoe eng

Tlhahlobo ea cholinesterase e khothaletsoa ke ngaka haholo-holo ho lekola boemo ba ho pepeseha ha lihoai, mohlala, meriana e bolaeang likokoanyana le chefo e bolaeang likokoanyana.

Ntle le moo, litekanyo tsa enzyme ena li ka kopuoa ho lekola bakuli ba nang le lefu la sebete, haholo-holo ba fetisitsoeng ka sebete, hobane hangata ba fokotse lipalo tsa cholinesterase.

Tekanyo ea cholinesterase e ka bonts'oa hape bakeng sa batho ba nang le liphetoho tse sitisang tšebetso e nepahetseng kapa tlhahiso ea enzyme ena.

Litekanyetso tsa litšupiso

Litekanyetso tsa tlhahlobo ea Cholinesterase li fapana ho latela laboratori le lisebelisoa tse sebelisetsoang ho etsa tlhahlobo. Kahoo, litekanyetso tse tloaelehileng tsa litšupiso li ka ba lipakeng tsa:

• Banna: 4620 - 11500 U / L.
• Basali: 3930 - 10800 U / L.

Teko ena e etsoa joalo ka tlhahlobo efe kapa efe ea mali, ke hore, sampole e nyane ea mali ea bokelloa ebe e romelloa laboratoring ho ea hlahlojoa ke lefapha la biochemistry. Ho latela laboratori ho ka khothaletsoa ho itima lijo bonyane lihora tse 4.

Seo liphetho li se bolelang

Uena maemo a tlase ea cholinesterase haholo-holo e bonts'a ho pepeseha ha nako e telele ho chefo e bolaeang likokoanyana ea organophosphate, e leng lintho tse fumanehang ho chefo e bolaeang likokoanyana, chefo e bolaeang likokonyana le likokoana-hloko tse nang le bokhoni ba ho thibela tšebetso ea enzyme ena, e lebisang ho bokelleng ha acetylcholine mme e ka hlahisang ponahalo ea matšoao le matšoao a mang, joalo ka :

• Likerethe;
• Letšollo;
• Ho hlatsa;
• Salivation e feteletseng;
• Bothata ba pono;
• Ho fokotsa khatello ea mali;
• Bofokoli ba mesifa;
• Ho shoa litho.

Le ha ho fokotseha ha maemo a cholinesterase ho amana haholo le tahi, ho kanna ha ba le ho fokotseha ha enzyme ena ha ho na le lefu la sebete, ho thatafala ha pelo, ho hloleha ha pelo, tšoaetso e matla le infarction.

Ka hona, ho bohlokoa hore liphetho tsa tlhahlobo ea cholinesterase li hlalosoe hammoho le litholoana tsa liteko tse ling e le hore sesosa sa ho fokotseha ha enzyme ena se tsejoe mme kalafo e nepahetseng ka ho fetisisa e ka bontšoa.

Ka hlakoreng le leng, maemo a phahameng ea cholinesterase, hangata e etsahala ka lebaka la botenya, lefu la tsoekere, lefu la nephrotic le hyperthyroidism.