Sengoli: Morris Wright
Letsatsi La Creation: 1 April 2021
Ntlafatsa Letsatsi: 10 November 2024
Anonim
What REALLY Happens When You Take Medicine?
Video: What REALLY Happens When You Take Medicine?

Litaba

Ts'ebeliso ea Ibuprofen le lithethefatsi tse ling tse sa anti-inflammatory (NSAIDs) nakong ea ts'oaetso le SARS-CoV-2 e nkuoa e bolokehile, hobane ho ne ho sa khonehe ho tiisa kamano lipakeng tsa ts'ebeliso ea lithethefatsi ena le ho mpefala ha matšoao a phefumoloho ea Seoa sa COVID.19.

Ntle le moo, phuputso e entsoe Iseraeleng [1] bakuli ba behiloeng leihlo ba sebelisitseng ibuprofen beke pele ho ts'oaetso ea COVID-19 le nakong ea kalafo ea phomolo ea matšoao hammoho le paracetamol mme ba fumana hore ts'ebeliso ea ibuprofen ha e amane le ho mpefala ha boemo ba bongaka ba bakuli.

Kahoo, ha ho na bopaki ba hore ts'ebeliso ea ibuprofen e ka eketsa ho kula le ho shoa ha COVID-19 mme, ka hona, ts'ebeliso ea moriana ona e bontšoa ke ba boholong bophelong, mme e lokela ho sebelisoa tlasa khothaletso ea bongaka.

Hobaneng ha ibuprofen e ka mpefatsa tšoaetso?

Phuputso e phatlalalitsoeng koranteng Meriana ea Phefumoloho ea Lancet [2] e bolela hore ibuprofen e ka mpefatsa matšoao ho batho ba nang le tšoaetso e matla ea phefumoloho ea vaerase, kaha setlhare sena se tla khona ho eketsa polelo ea ACE, e leng mokelikeli o teng liseleng tsa motho hape e tlamang coronavirus e ncha. Polelo ena e ipapisitse le taba ea hore bakuli ba nang le lefu la tsoekere le ba nang le khatello e phahameng ea mali ba na le palo e phahameng ea li-receptor tsa ACE, ibuprofen le li-NSAID tse ling mme ba thehile COVID-19 e matla.


Phuputso e 'ngoe e entsoe ka likhoto tsa batho ba nang le lefu la tsoekere[3], e khothalletsa ts'ebeliso ea ibuprofen libeke tse 8 ka tekanyetso e tlase ho feta kamoo ho khothalelitsoeng, ho hlahisang polelo e eketsehileng ea enzyme e fetolang angiotensin 2 (ACE2) meleng ea pelo.

Enzyme eona eo, ACE2, e bonahala e le e 'ngoe ea lintlha tsa ho kenella bakeng sa livaerase tsa lelapa la coronavirus liseleng, mme ka lebaka lena, bo-rasaense ba bang ba nahana hore haeba ho na le keketseho ea polelo ea enzyme ena bathong, haholoholo matšoafo, ho ka etsahala hore vaerase e ka ata ka potlako, e baka matšoao a matla le ho feta.

Se tsejoang

Leha lithuto li lokollotsoe ka kamano e mpe lipakeng tsa ibuprofen le COVID-19, Mokhatlo oa Lefatše oa Bophelo le ba bang ba boholong lefapheng la bophelo bo botle ba bonts'itse hore ha ho na bopaki ba mahlale ba hore ts'ebeliso ea ibuprofen e ne e ke ke ea bolokeha, hobane liphetho tse hlahisitsoeng li ne li ipapisitse le likhopolo lithuto tsa batho li hlile li entsoe. Ntle le moo, lithuto tse ling li bontšitse seo [4]:


  • Ha ho na bopaki bo tobileng ba hore ibuprofen e ka sebelisana le SARS-CoV-2;
  • Ha ho na bopaki ba hore ibuprofen e ikarabella bakeng sa ho eketsa polelo ea enzyme e fetolang angiotensin;
  • Boithuto bo bong ba in vitro bo bonts'itse hore ibuprofen e ka "roba" mokelikeli oa ACE, ea etsa hore ho be thata bakeng sa tšebelisano ea kokoana-hloko ea lisele le ho fokotsa kotsi ea vaerase e kenang ka seleng ka tsela ena;
  • Ha ho na bopaki ba hore ts'ebeliso ea ibuprofen e ka mpefatsa kapa ea eketsa kotsi ea tšoaetso.

Le ha ho le joalo, ho ntse ho hlokahala lithuto tse ling ho netefatsa ho ba sieo ha kamano lipakeng tsa SARS-CoV-2 le ts'ebeliso ea ibuprofen kapa li-NSAID tse ling le ho netefatsa ts'ebeliso e bolokehileng ea lithethefatsi tsena.

Seo u lokelang ho se etsa haeba u na le matšoao

Tabeng ea matšoao a bonolo a COVID-19, joalo ka feberu, ho khohlela ho matla le ho opeloa ke hlooho, ho etsa mohlala, ntle le ho itšehla thajana, ho kgothaletswa ho buisana le ngaka hore tataiso e ka fanoa mabapi le meriana e tla sebelisoa ho imolla letšoao, ts'ebeliso ea paracetamol kapa ibuprofen e kanna ea bonts'oa, e lokelang ho sebelisoa ho latela likeletso tsa bongaka.


Leha ho le joalo, ha matšoao a le matla haholo, mme ho ka ba le bothata ba ho hema le bohloko ba sefuba, ntho e ntle ke hore motho eo a ee sepetlele e le hore tlhahlobo ea COVID-19 e netefatsoe mme kalafo e khethehileng e ka qalisoa ka kalafo sepheo sa ho thibela mathata a mang le ho ntlafatsa bophelo ba motho. Utloisisa hore na kalafo e etsoa joang bakeng sa COVID-19.

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