Sengoli: Randy Alexander
Letsatsi La Creation: 28 April 2021
Ntlafatsa Letsatsi: 15 November 2024
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Litaba

Teko ea Aldosterone ke eng?

Teko ea aldosterone (ALD) e lekanya boholo ba ALD maling a hau. E boetse e bitsoa teko ea serum aldosterone. ALD ke hormone e entsoeng ke litšoelesa tsa adrenal. Litšoelesa tsa adrenal li fumaneha ka holim'a liphio tsa hau mme li na le boikarabello ba ho hlahisa lihormone tse 'maloa tsa bohlokoa. ALD e ama khatello ea mali hape e laola sodium (letsoai) le potasiamo maling a hao, har'a mesebetsi e meng.

ALD e ngata haholo e ka tlatsetsa khatello e phahameng ea mali le maemo a tlase a potasiamo. E tsejoa e le hyperaldosteronism ha 'mele oa hau o etsa ALD e ngata haholo. Hyperaldosteronism ea mantlha e ka bakoa ke hlahala ea adrenal (hangata e kotsi, kapa e sa chese kankere). Khabareng, hyperaldosteronism ea bobeli e ka bakoa ke maemo a fapaneng. Tsena li kenyelletsa:

  • congestive pelo hloleha
  • ho thatafala ha sebete
  • mafu a mang a liphio (mohlala, nephrotic syndrome)
  • potasiamo e feteletseng
  • sodium e tlaase
  • toxemia ho tloha bokhachane

Tlhahlobo ea Aldosterone e Fumana Eng?

Hangata ho sebelisoa tlhahlobo ea ALD ho fumana mathata a mokelikeli le a elektrolyte. Tsena li ka bakoa ke:


  • mathata a pelo
  • ho hloleha ha liphio
  • lefu la tsoekere insipidus
  • lefu la adrenal

Teko e ka thusa ho fumana:

  • khatello e phahameng ea mali eo ho leng thata ho e laola kapa e etsahala ho sa le monyane lilemong
  • orthostatic hypotension (khatello e tlase ea mali e bakoang ke ho ema)
  • tlhahiso e fetang ea ALD
  • ho haelloa ke adrenal (tlasa litšoelesa tse sebetsang tsa adrenal)

Ho lokisetsa tlhahlobo ea Aldosterone

Ngaka ea hau e ka u kopa ho etsa tlhahlobo ena ka nako e itseng ea letsatsi. Nako e bohlokoa, kaha maemo a ALD a fapana ho pholletsa le letsatsi. Methati e holimo haholo hoseng. Ngaka ea hau e kanna ea u kopa ho:

  • fetola palo ea sodium eo u e jang (e bitsoang lijo tsa thibelo ea sodium)
  • qoba ho ikoetlisa ka thata
  • qoba ho ja licorice (licorice e ka etsisa thepa ea aldosterone)
  • Lintlha tsena li ka ama maemo a ALD. Ho imeloa kelellong ho ka eketsa ALD ka nakoana.

Meriana e 'maloa e ka ama ALD. Bolella ngaka ea hau ka meriana eohle eo u e sebelisang. Sena se kenyelletsa litlatsetso le litlhare tse rekisoang. Ngaka ea hau e tla u joetsa hore na u hloka ho emisa kapa ho fetola meriana efe kapa efe pele ho tlhahlobo ena.


Meriana e ka amang ALD e kenyelletsa:

  • lithethefatsi tse seng khahlanong le ho ruruha (li-NSAID), joalo ka ibuprofen
  • diuretics (lipilisi tsa metsi)
  • lithibela-pelehi tsa molomo
  • angiotensin-converting enzyme (ACE) inhibitors, joalo ka benazepril
  • li-steroids, tse kang prednisone
  • beta blockers, joalo ka bisoprolol
  • li-block channel tsa calcium, tse kang amlodipine
  • lithium
  • heparine
  • propranolol

Teko ea Aldosterone e Etsoa Joang

Tlhahlobo ea ALD e hloka sampole ea mali. Sampole ea mali e ka nkoa ofising ea ngaka kapa ea etsoa laboratoring.

Taba ea mantlha, mofani oa tlhokomelo ea bophelo o tla silafatsa sebaka se letsohong kapa letsohong la hau. Ba tla thatela lebanta le rekereng letsohong la hau le kaholimo ho etsa hore mali a bokelle methapong. Ka mor'a moo, ba tla kenya nale e nyane mothapong oa hau. Sena se ka utloisa bohloko hanyane hanyane mme se ka baka hlaba kapa ho hlaba. Mali a tla bokelloa ka mothong o le mong kapa ho feta.


Mofani oa hau oa tlhokomelo ea bophelo o tla tlosa bland le nale, mme ba tla kenya khatello ho phunya ho emisa ho tsoa mali le ho thusa ho thibela ho longoa. Ba tla tlotsa bandage sebakeng sa ho phunya. Sebaka sa marang-rang se kanna sa tsoela pele ho putlama, empa sena se fela kamora metsotso e seng mekae ho batho ba bangata.

Likotsi tsa ho huloa mali a hau li tlase. E nkuoa e le teko ea bongaka e sa hlaseleng. Likotsi tse ka bang teng tsa ho huloa mali li kenyelletsa:

  • mahlaba a mangata a nale ka baka la bothata ba ho fumana mothapo
  • ho tsoa madi haholo
  • bohlooho kapa ho idibala
  • hematoma (ho kopanya mali ka tlas'a letlalo)
  • ts'oaetso sebakeng sa ho phunya

Ho fetolela liphetho tsa hau

Ngaka ea hau e tla lekola lintlha tse bokelletsoeng ke tlhahlobo. Ba tla u atamela hamorao ho buisana ka liphetho tsa hau.

Maemo a phahameng a ALD a bitsoa hyperaldosteronism. Sena se ka eketsa potasiamo ea mali le sodium e tlase. Hyperaldosteronism e ka bakoa ke:

  • renal artery stenosis (ho fokotsa methapo e fanang ka mali ho liphio)
  • congestive pelo hloleha
  • lefu la liphio kapa ho hloleha
  • cirrhosis (scarring ea sebete) toxemia ea bokhachane
  • lijo tse nang le sodium e fokolang haholo
  • Conn syndrome, Cushing's syndrome, kapa Bartter syndrome (ka seoelo)

Maemo a tlase a ALD a bitsoa hypoaldosteronism. Matšoao a boemo bona a kenyelletsa:

  • khatello e tlase ea mali
  • ho felloa ke metsi 'meleng
  • maemo a tlase a sodium
  • maemo a tlase a potasiamo

Hypoaldosteronism e ka bakoa ke:

  • ho haella ha adrenal
  • Lefu la Addison, le amang tlhahiso ea lihomone tsa adrenal
  • hyporeninemic hypoaldosteronism (ALD e tlase e bakoang ke lefu la liphio)
  • lijo tse nang le sodium e phahameng haholo (ho feta 2,300 mg / letsatsi bakeng sa ba lilemo li 50 le tlase; 1,500 ho feta lilemo tse 50)
  • congenital adrenal hyperplasia (boloetse ba pelehi boo masea a hlokang enzyme e hlokahalang ho etsa cortisol, e ka amang tlhahiso ea ALD hape.)

Kamora Teko

Hang ha ngaka ea hau e se e hlahlobile sephetho sa hau le uena, e kanna ea odara liteko tse ling ho thusa ho fumana tlhahiso ea ALD. Liteko tsena li kenyelletsa:

  • renin ea lero la mali
  • renin-ALD karo-karolelano
  • andrenocorticotrophin (ACTH) ho tšeloa
  • khopotso
  • ho tšeloa letsoai ka intravenous (IV)

Liteko tsena li tla thusa uena le ngaka ea hau ho ithuta haholoanyane ka se bakang bothata ka ALD ea hau.Sena se tla thusa ngaka ea hau ho fumana tlhahlobo le ho tla le moralo oa kalafo.

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