CSF myelin protheine ea mantlha
Protheine ea mantlha ea CSF ke teko ea ho lekanya boemo ba protheine ea myelin basic (MBP) ho cerebrospinal fluid (CSF).
CSF ke mokelikeli o hlakileng o pota-potileng boko le lesapo la mokokotlo.
MBP e fumaneha boitsebisong bo koahelang methapo ea hau e mengata.
Mohlala oa mokelikeli oa mokokotlo oa hlokahala. Sena se etsoa ka ho phunya lumbar.
Teko ena e etsoa ho bona hore na myelin ea senyeha. Multiple sclerosis ke sesosa se tloaelehileng ho sena, empa lisosa tse ling li ka kenyelletsa:
- Ho tsoa mali tsamaisong ea methapo e bohareng
- Matšoenyeho a tsamaiso ea methapo e bohareng
- Maloetse a mang a boko (encephalopathies)
- Tšoaetso ea tsamaiso ea methapo e bohareng
- Leqeba
Ka kakaretso, ho lokela hore ho be le tlase ho 4 ng / mL ea protheine ea myelin ea mantlha ho CSF.
Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Bua le mofani oa tlhokomelo ea bophelo mabapi le moelelo oa sephetho sa hau sa liteko.
Mohlala o kaholimo o bonts'a sephetho se tloaelehileng sa litekanyo tsa teko ena. Li laboratori tse ling li sebelisa litekanyo tse fapaneng kapa li ka leka mefuta e fapaneng.
Methati ea protheine ea Myelin lipakeng tsa 4 le 8 ng / mL e kanna ea ba sesupo sa ho senyeha ha myelin ea nako e telele (e sa foleng). E kanna ea bonts'a ho hlaphoheloa ketsahalong e bohloko ea ho senyeha ha myelin.
Haeba protheine ea myelin ea mantlha e feta 9 ng / mL, myelin e ntse e senyeha ka mafolofolo.
- Lumbar puncture (pompo ea mokokotlo)
Fabian MT, Krieger SC, Lublin FD. Multiple sclerosis le mafu a mang a ho ruruha a fokolisang methapo ea methapo. Ka: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, bahlophisi. Neurology ea Bradley ho Tloaelo ea Bongaka. La 7th. Philadelphia, PA: Elsevier; 2016: khaolo ea 80.
Karcher DS, McPherson RA. Cerebrospinal, synovial, maro a 'mele oa serous le mefuta e meng. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 29.