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Letsatsi La Creation: 24 Phupu 2021
Ntlafatsa Letsatsi: 1 November 2024
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Ho hlahisa li-ovaria ho feta tekano ke boemo boo mae a bomme a etsang testosterone e ngata haholo. Sena se lebisa ho nts'etsopele ea litšobotsi tsa monna ho mosali. Androgens e tsoang likarolong tse ling tsa 'mele le eona e ka baka litšobotsi tsa banna ho hola ho basali.

Basali ba phetseng hantle, mae a bomme le litšoelesa tsa adrenal li hlahisa 40% ho 50% ea testosterone ea 'mele. Lihlahala tsa mae a bomme le polycystic ovary syndrome (PCOS) ka bobeli li ka baka tlhahiso e ngata ea androgen.

Boloetse ba cushing ke bothata ba tšoelesa ea pituitary e lebisang ho li-corticosteroids tse ngata. Corticosteroids e baka phetoho ea mmele ho basali. Lihlahala tsa litšoelesa tsa adrenal le tsona li ka baka tlhahiso e ngata haholo ea li-androgen mme li ka lebisa ho litšobotsi tsa 'mele oa banna ho basali.

Mefuta e phahameng ea li-androgens ho mosali e ka baka:

  • Makhopho
  • Liphetoho sebopeho sa basali
  • Fokotseha ka boholo ba matsoele
  • Eketsa moriri oa 'mele ka mokhoa oa monna, joalo ka sefahlehong, seledung le mpeng
  • Ho hloka nako ea ho ilela khoeli (amenorrhea)
  • Letlalo le mafura

Liphetoho tsena li kanna tsa etsahala hape:


  • Eketsa ka boholo ba clitoris
  • Ho teba ha lentsoe
  • Eketsa mesifa
  • Ho kuta moriri le ho lahleheloa ke moriri ka pele hloohong mahlakore ka bobeli a hlooho

Mofani oa hao oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele. Liteko life kapa life tsa mali le litšoantšo tse laetsoeng li tla latela matšoao a hau, empa li ka kenyelletsa:

  • Teko ea 17-hydroxyprogesterone
  • Teko ea ACTH (e sa tloaelehang)
  • Liteko tsa mali tsa cholesterol
  • CT scan
  • Teko ea mali ea DHEA
  • Teko ea tsoekere
  • Teko ea insulin
  • Pelvic ultrasound
  • Teko ea Prolactin (haeba linako li sa tla hangata kapa che)
  • Teko ea testosterone (testosterone ea mahala le e felletseng)
  • Teko ea TSH (haeba ho na le tahlehelo ea moriri)

Kalafo e ipapisitse le bothata bo bakang tlhahiso e eketsehileng ea androgen. Meriana e ka fanoa ho fokotsa tlhahiso ea moriri ho basali ba nang le moriri o feteletseng oa 'mele, kapa ho laola linako tsa ho ilela khoeli. Maemong a mang, ho ka hlokahala opereishene ho tlosa hlahala ea mahe a bomme kapa adrenal.


Katleho ea kalafo e latela sesosa sa tlhahiso e fetelletseng ea androgen. Haeba boemo bo bakoa ke hlahala ea mahe a bomme, ho buuoa ho tlosa hlahala ho ka lokisa bothata. Boholo ba lihlahala tsa mae a bomme ha li na mofets'e (li kotsi) 'me ha li na ho khutla kamora hore li tlosoe.

Ho polycystic ovary syndrome, mehato e latelang e ka fokotsa matšoao a bakoang ke maemo a phahameng a androgen:

  • Tlhokomelo e hlokolosi
  • Ho fokotsa boima ba 'mele
  • Liphetoho tsa lijo
  • Meriana
  • Ho ikoetlisa ka matla kamehla

Ho hloka thari le mathata nakong ea bokhachane li ka hlaha.

Basali ba nang le polycystic ovary syndrome ba ka ba kotsing e kholo ea:

  • Lefu la tsoekere
  • Khatello ea mali e phahameng
  • Cholesterol e phahameng
  • Botenya
  • Kankere ea popelo

Basali ba nang le polycystic ovary syndrome ba ka fokotsa liphetoho tsa mathata a nako e telele ka ho boloka boima bo tloaelehileng ka ho ja lijo tse nepahetseng le ho ikoetlisa khafetsa.

  • Ho hlahisa mae a bomme haholo
  • Nts'etsopele ea folakha

Bulun SE. Physiology le pathology ea karolo ea basali ea ho ikatisa. Ka: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, bahlophisi. Buka ea Williams ea Endocrinology. La bo14 la ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 17.


Huddleston HG, Quinn M, Gibson M. Polycystic ovary syndrome le hirsutism. Ka: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, bahlophisi. Buka ea Nelson ea Pediatrics. La 21 Ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 567.

Lobo RA. Hyperandrogenism le fetello ea androgen: physiology, etiology, phapang ea phapang, taolo. Ka: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Kakaretso ea mafu a basali. La 7th. Philadelphia, PA: Elsevier; 2017: khaolo ea 40.

Rosenfield RL, Barnes RB, Ehrmann DA. Hyperandrogenism, hirsutism, le lefu la ovary la polycystic. Ka: Jameson JL, De Groot LJ, oa Kretser DM, et al, eds. Endocrinology: Batho ba baholo le bana. La 7th. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 133.

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