Ho haella ha factor XII (Hageman factor)

Khaello ea factor XII ke lefu le futsitsoeng le amang protheine (factor XII) e amehang ho hoamang mali.

Ha o tsoa mali, letoto la liketso li etsahala 'meleng o thusang ho hlama ha mali. Ts'ebetso ena e bitsoa coagulation cascade. E kenyelletsa liprotheine tse ikhethang tse bitsoang coagulation kapa clotting factor. U ka ba le monyetla o moholo oa ho tsoa mali a mangata haeba e le 'ngoe kapa tse ling tsa lintlha tsena li le sieo kapa li sa sebetse kamoo li lokelang ho sebetsa kateng.

Ntlha XII ke e 'ngoe ea lintlha tse joalo. Ho haella ha ntlha ena ha ho bake hore u tsoe mali ka mokhoa o sa tloaelehang. Empa, mali a nka nako e teletsana ho feta e tloaelehileng ho koala tube ea teko.

Khaello ea factor XII ke lefu le sa tloaelehang le futsitsoeng.

Hangata ha ho na matšoao.

Ho haella ha factor XII ho fumaneha hangata ha liteko tsa ho koala li etsoa bakeng sa tlhahlobo ea ka mehla.

Liteko li ka kenyelletsa:

• Ntlha ea XII ea liteko ho lekanya ts'ebetso ea factor XII
• Nako ea karoloana ea thromboplastin (PTT) ho lekola hore na ho nka nako e kae hore mali a hoama
• Ho kopanya thuto, teko e khethehileng ea PTT ho netefatsa khaello ea factor XII

Kalafo hangata ha e hlokahale.

Lisebelisoa tsena li ka fana ka tlhaiso-leseling e batsi ka khaello ea factor XII:

• Setsi sa Naha sa Haemophilia - www.hemophilia.org/Bleeding-Disorder/Types-of-Bleeding-Disorders/Other-Factor-Deficiencies/Factor-XII
• Mokhatlo oa Naha oa Mathata a Rare - rarediseases.org/rare-diseases/factor-xii-deficiency
• Setsi sa Boitsebiso ba Mafu le a Rare a mafu a sa tloaelehang - rarediseases.info.nih.gov/diseases/6558/factor-xii-deficiency

Sephetho se lebelletsoe ho ba ntle ntle le kalafo.

Hangata ha ho na mathata.

Mofani oa tlhokomelo ea bophelo hangata o fumana boemo bona ha a etsa liteko tse ling tsa laboraka.

Ena ke lefu le futsitsoeng. Ha ho na mokhoa o tsebahalang oa ho e thibela.

Khaello ea F12; Ho haella ha factor ea Hageman; Tšobotsi ea Hageman; Khaello ea HAF

• Ho koala mali

Gailani D, Wheeler AP, Neff AT. Mathata a sa tloaelehang a li-coagulation. Ka: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Melao-motheo le Tloaelo ea Motheo. La 7th. Philadelphia, PA: Elsevier; 2018: khaolo ea 137.

Holo ea JE. Hemostasis le coagulation ea mali. Ka: Holo ea JE, ed. Buka ea Guyton le Hall ea Physiology ea Bongaka. 13th ed. Philadelphia, PA: Elsevier; 2016: khaolo ea 37.

Ragni MV. Mathata a hemorrhagic: ho haelloa ke lebaka la coagulation. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 174.