Glomerulosclerosis e shebaneng le karolo

Focal segmental glomerulosclerosis ke lisele tse bohale sehlopheng sa ho sefa ea liphio. Sebopeho sena se bitsoa glomerulus. Li-glomeruli li sebetsa e le li-filters tse thusang 'mele ho felisa lintho tse kotsi. Phio ka 'ngoe e na le glomeruli e likete.

"Focal" e bolela hore tse ling tsa glomeruli li ba le mabali. Tse ling li lula li tloaelehile. "Segmental" e bolela hore ke karolo feela ea glomerulus ka bomong e senyehileng.

Lebaka la glomerulosclerosis e shebaneng haholo le likarolo hangata ha le tsejoe.

Boemo bona bo ama bana le batho ba baholo. E hlaha hangata hanyane ho banna le bashanyana. E boetse e atile haholo ho batho ba Afrika Boroa. Focal segmental glomerulosclerosis e baka kotara ea linyeoe tsohle tsa lefu la nephrotic.

Lisosa tse tsebahalang li kenyelletsa:

• Lithethefatsi tse kang heroin, bisphosphonates, anabolic steroids
• Tšoaetso
• Mathata a liphatsa tsa lefutso
• Botenya
• Reflux nephropathy (boemo boo moroto o phallelang morao ho tloha senya ho ea liphio)
• Boloetse ba sele
• Meriana e meng

Matšoao a ka kenyelletsa:

• Motsoako oa foam (ho tsoa liprotheine tse ngata morotong)
• Takatso e fosahetseng ea lijo
• Ho ruruha, ho bitsoang edema e akaretsang, ho tsoa maro a tšoaroang 'meleng
• Boima ba 'mele

Mofani oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele. Teko ena e kanna ea bontša ho ruruha hoa lisele (edema) le khatello e phahameng ea mali. Matšoao a ho hloleha ha liphio (renal) le mokelikeli o feteletseng li ka hlaha ha boemo bo ntse bo mpefala.

Liteko li ka kenyelletsa:

• Liphio biopsy
• Liteko tsa ts'ebetso ea liphio (mali le moroto)
• Ho hlahloba urinal
• Microscopy ea moroto
• Protheine ea moroto

Kalafo e ka kenyelletsa:

• Meriana e fokotsang karabelo ea 'mele ea ho ruruha.
• Meriana ea ho theola khatello ea mali. E meng ea meriana ena e boetse e thusa ho fokotsa bongata ba protheine e tšolohelang ka morong.
• Meriana ea ho felisa mokelikeli o feteletseng (diuretic kapa "pilisi ea metsi").
• Lijo tse tlase tsa sodium ho fokotsa ho ruruha le khatello e tlase ea mali.

Morero oa kalafo ke ho laola matšoao a nephrotic syndrome le ho thibela ho hloleha ha liphio ho sa foleng. Litlhare tsena li ka kenyelletsa:

• Lithibela-mafu ho laola tšoaetso
• Thibelo ea metsi
• Lijo tse se nang mafura a mangata
• Lijo tse tlase kapa tse itekanetseng tsa protheine
• Vithamine D e tlatsetsa
• Dialysis
• Ho kenyelletsa liphio

Karolo e kholo ea batho ba nang le glomerulosclerosis e tsepameng kapa e arohaneng e tla ba le ho hloleha ho sa foleng ha liphio.

Mathata a ka kenyelletsa:

• Ho hloleha ha liphio ho sa foleng
• Boloetse ba liphio qetellong
• Tšoaetso
• Khaello ea phepo e nepahetseng
• Lefu la Nephrotic

Bitsa mofani oa hau haeba u ba le matšoao a boemo bona, haholo haeba ho na le:

• Feberu
• Bohloko ba ho ntša metsi
• Ho fokotsa tlhahiso ea moroto

Ha ho thibelo e tsejoang.

Karolo ea glomerulosclerosis; Focal sclerosis le hyalinosis

• Tsamaiso ea monna ea ho ntša metsi

Appel GB, D'Agati VD. Lisosa tsa mantlha le tsa bobeli (eseng lefutso) lisosa tsa glomerulosclerosis e tsepameng le e arohaneng. Ho: Feehally J, Floege J, Tonelli M, Johnson RJ, bangoli. Kakaretso ea Nephrology ea Kliniki. La 6th. Philadelphia, PA: Elsevier; 2019: khaolo ea 18.

Appel GB, mafu a Radhakrishnan J. Glomerular le li-syndromes tsa nephrotic. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil.La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 121.

Pendergraft WF, Nachman PH, Jennette JC, Falk RJ. Lefu la mantlha la glomerular. Ka: Skorecki K, Taal MW, Chertow GM, Marsden PA, Yu ASL, li-eds. Brenner le Rector ea Liphio. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 32.